Modelling Electrophysiological Data in Persistent Atrial Fibrillation Studies Using the Evolution of 3-Dimensional Dominant Frequency Mapping

2017 ◽  
pp. 160-171
Author(s):  
Priscilla Sim Chee Mei ◽  
Nurul Adilla Mohd Subha ◽  
Anita Ahmad
Keyword(s):  
Atrial Fibrillation ◽  
Persistent Atrial Fibrillation ◽  
Dominant Frequency ◽  
3 Dimensional ◽  
Electrophysiological Data

The Relationship Between Electrogram Cycle Length and Dominant Frequency in Patients with Persistent Atrial Fibrillation

2009 ◽  
Vol 20 (12) ◽  
pp. 1336-1342 ◽  
Author(s):  
SHELDON M. SINGH ◽  
E. KEVIN HEIST ◽  
JACOB S. KORUTH ◽  
CONOR D. BARRETT ◽  
JEREMY N. RUSKIN ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Cycle Length ◽  
Persistent Atrial Fibrillation ◽  
Dominant Frequency ◽  
The Relationship

scholarly journals Endocardial-Epicardial Phase Mapping of Prolonged Persistent Atrial Fibrillation Recordings

2020 ◽  
Vol 13 (8) ◽  
Author(s):  
Ramanathan Parameswaran ◽  
Jonathan M. Kalman ◽  
Alistair Royse ◽  
John Goldblatt ◽  
Marco Larobina ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Persistent Atrial Fibrillation ◽  
Temporal Heterogeneity ◽  
Activation Patterns ◽  
3 Dimensional ◽  
Transmural Migration ◽  
Endocardial Mapping ◽  
Phase Mapping ◽  
Insight Into ◽  
Activation Mapping

Background: Endocardial-epicardial dissociation and focal breakthroughs in humans with atrial fibrillation (AF) have been recently demonstrated using activation mapping of short 10-second AF segments. In the current study, we used simultaneous endo-epi phase mapping to characterize endo-epi activation patterns on long segments of human persistent AF. Methods: Simultaneous intraoperative mapping of endo- and epicardial lateral right atrium wall was performed in patients with persistent AF using 2 high-density grid catheters (16 electrodes, 3 mm spacing). Filtered unipolar and bipolar electrograms of continuous 2-minute AF recordings and electrodes locations were exported for phase analyses. We defined endocardial-epicardial dissociation as phase difference of ≥20 ms between paired endo-epi electrodes. Wavefronts were classified as rotations, single wavefronts, focal waves, or disorganized activity as per standard criteria. Endo-Epi wavefront patterns were simultaneously compared on dynamic phase maps. Complex fractionated electrograms were defined as bipolar electrograms with ≥5 directional changes occupying at least 70% of sample duration. Results: Fourteen patients with persistent AF undergoing cardiac surgery were included. Endocardial-epicardial dissociation was seen in 50.3% of phase maps with significant temporal heterogeneity. Disorganized activity (Endo: 41.3% versus Epi: 46.8%, P =0.0194) and single wavefronts (Endo: 31.3% versus Epi: 28.1%, P =0.129) were the dominant patterns. Transient rotations (Endo: 22% versus Epi: 19.2%, P =0.169; mean duration: 590±140 ms) and nonsustained focal waves (Endo: 1.2% versus Epi: 1.6%, P =0.669) were also observed. Apparent transmural migration of rotational activations (n=6) from the epi- to the endocardium was seen in 2 patients. Electrogram fractionation was significantly higher in the epicardium than endocardium (61.2% versus 51.6%, P <0.0001). Conclusions: Simultaneous endo-epi phase mapping of prolonged human persistent AF recordings shows significant Endocardial-epicardial dissociation marked temporal heterogeneity, discordant and transitioning wavefronts patterns and complex fractionations. No sustained focal activity was observed. Such complex 3-dimensional interactions provide insight into why endocardial mapping alone may not fully characterize the AF mechanism and why endocardial ablation may not be sufficient. Graphic Abstract: A graphic abstract is available for this article.

A critical decrease in dominant frequency and clinical outcome after catheter ablation of persistent atrial fibrillation

Heart Rhythm ◽  
2010 ◽  
Vol 7 (3) ◽  
pp. 295-302 ◽  
Author(s):  
Kentaro Yoshida ◽  
Aman Chugh ◽  
Eric Good ◽  
Thomas Crawford ◽  
James Myles ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Clinical Outcome ◽  
Persistent Atrial Fibrillation ◽  
Dominant Frequency

scholarly journals B-PO04-091 INTRACARDIAC DOMINANT FREQUENCY, BUT NOT BIPOLAR ELECTROGRAM VOLTAGE, CORRELATES WITH ABLATION OUTCOMES IN PERSISTENT ATRIAL FIBRILLATION

Heart Rhythm ◽  
2021 ◽  
Vol 18 (8) ◽  
pp. S316
Author(s):  
Anna McCann ◽  
Adrian Luca ◽  
Julia Fenwick ◽  
Andrea Buttu ◽  
Jean-Marc Vesin ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Persistent Atrial Fibrillation ◽  
Dominant Frequency ◽  
Electrogram Voltage

scholarly journals Posters 159Misdiagnosed, misbelieved and misdirected; largest uk study casts doubt on some long held but poorly validated assumptions about the pots population and suggests improvements in care pathways and service provision60An acute comparison of different strategies for targeting the left ventricular lead for cardiac resynchronisation therapy61Relationship of phase singularities and high dominant frequency regions during persistent atrial fibrillation in humans62Restoration of sinus rhythm results in early and late improvements in the functional reserve of the heart following direct current cardioversion of persistent af: fresh-af63Non-concomitant hybrid ablation using the estech cobra device for the treatment of longstanding persistent atrial fibrillation: an initial single-centre experience64Artificial intelligence outperforms manual ecg scoring in the detection of arrhythmia substrate65Single centre experience and outcome of persistent af ablation using nmarq catheter: 2 year follow up66The growing burden of atrial fibrillation and management at a typical district general hospital67Haemodynamic effects of single-vein, simultaneous, multipoint pacing compared with bipolar pacing in patients undergoing cardiac resynchronisation therapy68Is multisite pacing of interest in cardiac resynchronization therapy? teachings from a long-term follow-up of a cohort of patients implanted with triventricular pacing systems69Differences in fractionated electrogram detection: a direct quantitative comparison between navx and carto: Table 1

EP Europace ◽  
2015 ◽  
Vol 17 (suppl 5) ◽  
pp. v18-v21
Author(s):  
L.A. Kavi ◽  
J.H.P. Gamble ◽  
N. Dastagir ◽  
K.A. Gilbert ◽  
G.O. Furniss ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Persistent Atrial Fibrillation ◽  
Dominant Frequency ◽  
Left Ventricular ◽  
Cardiac Resynchronization ◽  
Direct Current Cardioversion ◽  
Ventricular Lead ◽  
Cardiac Resynchronisation ◽  
Long Term Follow Up ◽  
Phase Singularities

scholarly journals Transient Rotor Activity During Prolonged 3-Dimensional Phase Mapping in Human Persistent Atrial Fibrillation

2018 ◽  
Vol 4 (1) ◽  
pp. 72-83 ◽  
Author(s):  
Bhupesh Pathik ◽  
Jonathan M. Kalman ◽  
Tomos Walters ◽  
Pawel Kuklik ◽  
Jichao Zhao ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Persistent Atrial Fibrillation ◽  
3 Dimensional ◽  
Phase Mapping
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