Mobile government transform many of the traditional governance practices. The citizens’ adoption of M-Government services (e.g. voting, tax services, health services, etc.), however, is determined by a series of factors (e.g. ease of use, image, compatibility, etc.). This chapter investigates the predicting power of these factors towards contributing to theory building and providing direct implications that are useful for the diffusion and adoption of mobile government services in Greece. The study reviews the available literature on adoption and diffusion of innovation as well as the available relevant research insights on the mobile commerce landscape. Then, the study empirically tests the predicting power of aseries of critical variables that are theoretically related to the Greek citizens’ intention to adopt mobile government services. The findings imply that compatibility and ease of use have significant predicting power on citizens’ intention to adopt M-Government services. Direct implications and further research directions are provided at the end.