Numerical Analysis of Wall Shear Stress Parameters of Newtonian Pulsatile Blood Flow Through Coronary Artery and Correlation to Atherosclerosis

Author(s):  
Abdulrajak Buradi ◽  
Arun Mahalingam
2018 ◽  
Vol 2018 ◽  
pp. 1-16 ◽  
Author(s):  
Mongkol Kaewbumrung ◽  
Somsak Orankitjaroen ◽  
Pichit Boonkrong ◽  
Buraskorn Nuntadilok ◽  
Benchawan Wiwatanapataphee

A mathematical model of dispersed bioparticle-blood flow through the stenosed coronary artery under the pulsatile boundary conditions is proposed. Blood is assumed to be an incompressible non-Newtonian fluid and its flow is considered as turbulence described by the Reynolds-averaged Navier-Stokes equations. Bioparticles are assumed to be spherical shape with the same density as blood, and their translation and rotational motions are governed by Newtonian equations. Impact of particle movement on the blood velocity, the pressure distribution, and the wall shear stress distribution in three different severity degrees of stenosis including 25%, 50%, and 75% are investigated through the numerical simulation using ANSYS 18.2. Increasing degree of stenosis severity results in higher values of the pressure drop and wall shear stresses. The higher level of bioparticle motion directly varies with the pressure drop and wall shear stress. The area of coronary artery with higher density of bioparticles also presents the higher wall shear stress.


Author(s):  
B.J.B.M. Wolters ◽  
C.J. Slager ◽  
F.J.H. Gijsen ◽  
J.J. Wentze ◽  
R. Krams ◽  
...  

Author(s):  
Kimie Onogi ◽  
Kazuhiro Kohge ◽  
Kiyoshi Minemura

This article illustrates numerical results on pulsating blood flow through moderately stenosed blood vessel. Two kinds of waveform, that is, a purely sinusoidal waveform and a non-sinusoidal one just like human blood flow are calculated for two cases of heart rate as 60 and 160 (1/s), and resultant flow behavior such as flow velocities, secondary flow, wall shear stress and pressure change are discussed. The abrupt changes in the pressure and wall shear stress occur on the throat of the stenosis, suggesting that this part is easily damaged by the effects when the heart rate is increased.


2003 ◽  
Vol 125 (2) ◽  
pp. 207-217 ◽  
Author(s):  
E. A. Finol ◽  
K. Keyhani ◽  
C. H. Amon

In the abdominal segment of the human aorta under a patient’s average resting conditions, pulsatile blood flow exhibits complex laminar patterns with secondary flows induced by adjacent branches and irregular vessel geometries. The flow dynamics becomes more complex when there is a pathological condition that causes changes in the normal structural composition of the vessel wall, for example, in the presence of an aneurysm. This work examines the hemodynamics of pulsatile blood flow in hypothetical three-dimensional models of abdominal aortic aneurysms (AAAs). Numerical predictions of blood flow patterns and hemodynamic stresses in AAAs are performed in single-aneurysm, asymmetric, rigid wall models using the finite element method. We characterize pulsatile flow dynamics in AAAs for average resting conditions by means of identifying regions of disturbed flow and quantifying the disturbance by evaluating flow-induced stresses at the aneurysm wall, specifically wall pressure and wall shear stress. Physiologically realistic abdominal aortic blood flow is simulated under pulsatile conditions for the range of time-average Reynolds numbers 50⩽Rem⩽300, corresponding to a range of peak Reynolds numbers 262.5⩽Repeak⩽1575. The vortex dynamics induced by pulsatile flow in AAAs is depicted by a sequence of four different flow phases in one period of the cardiac pulse. Peak wall shear stress and peak wall pressure are reported as a function of the time-average Reynolds number and aneurysm asymmetry. The effect of asymmetry in hypothetically shaped AAAs is to increase the maximum wall shear stress at peak flow and to induce the appearance of secondary flows in late diastole.


2010 ◽  
Vol 2010 ◽  
pp. 1-26 ◽  
Author(s):  
D. S. Sankar

Pulsatile flow of a two-fluid model for blood flow through stenosed narrow arteries is studied through a mathematical analysis. Blood is treated as two-phase fluid model with the suspension of all the erythrocytes in the as Herschel-Bulkley fluid and the plasma in the peripheral layer as a Newtonian fluid. Perturbation method is used to solve the system of nonlinear partial differential equations. The expressions for velocity, wall shear stress, plug core radius, flow rate and resistance to flow are obtained. The variations of these flow quantities with stenosis size, yield stress, axial distance, pulsatility and amplitude are analyzed. It is found that pressure drop, plug core radius, wall shear stress and resistance to flow increase as the yield stress or stenosis size increases while all other parameters held constant. It is observed that the percentage of increase in the magnitudes of the wall shear stress and resistance to flow over the uniform diameter tube is considerably very low for the present two-fluid model compared with that of the single-fluid model of the Herschel-Bulkley fluid. Thus, the presence of the peripheral layer helps in the functioning of the diseased arterial system.


Author(s):  
Sapna Ratan Shah ◽  
S. U. Siddiqui

This study focuses on the behavior of blood flow through diseased artery in the presence of porous effects. The laminar, incompressible, fully developed, non-Newtonian in an artery having axially non-symmetric but radially symmetric stenosis is numerically studied. Here blood is represented as Herschel-Bulkley fluid model and flow model is shown by the Navier-Stokes and the continuity equations. Using appropriate boundary conditions, numerical expression for volumetric flow rate, pressure drop and wall shear stress have been derived. The expressions are computed numerically and results are presented graphically. The effects of porous parameter on wall shear stress, stenosis length, stenosis size and stenosis shape parameter are discussed. The wall shear stress increases as the porous parameter, stenosis size and stenosis length increases, but as the stenosis shape parameter increases, the wall shear stress decreases. The work shows that the results obtained from the porous wall model are significantly different from those obtained by the rigid wall model.


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