Miss Rate Estimation (MRE) an Novel Approach Toward L2 Cache Partitioning Algorithm’s for Multicore System

2020 ◽  
pp. 593-603
Author(s):  
Pallavi Joshi ◽  
M. V. Rathnamma ◽  
K. Srujan Raju ◽  
Urmila Pawar
Keyword(s):  
Cache Partitioning ◽  
Rate Estimation ◽  
Novel Approach ◽  
L2 Cache ◽  
Multicore System

scholarly journals Adaptive Zone-Aware Multi-bank on Chip last level L2 Cache Partitioning for Chip Multiprocessors

2010 ◽  
Vol 7 (1) ◽  
pp. 19-23
Author(s):  
Nitin Chaturvedi ◽  
Jithin P Thomas ◽  
S Gurunarayanan
Keyword(s):  
Chip Multiprocessors ◽  
Cache Partitioning ◽  
L2 Cache ◽  
On Chip ◽  
Adaptive Zone

scholarly journals Target Doppler Rate Estimation Based on the Complex Phase of STFT in Passive Forward Scattering Radar

Sensors ◽  
2019 ◽  
Vol 19 (16) ◽  
pp. 3627 ◽  
Author(s):  
Karol Abratkiewicz ◽  
Piotr Krysik ◽  
Zbigniew Gajo ◽  
Piotr Samczyński
Keyword(s):  
Real Life ◽  
Simulated Data ◽  
Forward Scattering ◽  
Complex Phase ◽  
Time Frequency ◽  
Rate Estimation ◽  
Novel Approach ◽  
Real Life Data ◽  
Scattering Geometry ◽  
Short Time

This article presents a novel approach to the estimation of motion parameters of objects in passive forward scattering radars (PFSR). In such systems, most frequency modulated signals which are used have parameters that depend on the geometry of a radar scene and an object’s motion. Worth noting is that in bistatic (or multistatic) radars forward scattering geometry is present thus in this case only Doppler measurements are available while the range measurement is unambiguous. In this article the modulation factor, also called the Doppler rate, was determined based on the chirp rate (equivalent Doppler rate) estimation concept in the time-frequency (TF) domain. This approach utilizes the idea of the complex phase of the short-time Fourier transform (STFT) and its modification known from the literature. Mathematical dependencies were implemented and verified and the simulation results were described. The accuracy of the considered estimators were also verified using the Cramer-Rao lower bound (CRLB) to which simulated data for the considered estimators was compared. The proposed method was validated using a real-life signal collected from a radar operating in PFSR geometry. The Doppler rate provided by a car crossing the baseline between the receiver and the GSM transmitter was estimated. Finally, the concept of using CR estimation, which in the case of PFSR can be understood as Doppler rate, was confirmed on the basis of both simulated and real-life data.

Growth Rate Estimation of algae in Raceway Ponds: A novel Approach

2014 ◽  
Vol 47 (3) ◽  
pp. 6216-6221 ◽  
Author(s):  
Philipp Hartmann ◽  
David Demory ◽  
Charlotte Combe ◽  
Raouf Hamouda ◽  
Anne-Céline Boulanger ◽  
...  
Keyword(s):  
Growth Rate ◽  
Rate Estimation ◽  
Novel Approach ◽  
Raceway Ponds

Copper-dependent ATP7B up-regulation drives the resistance of TMEM16A-overexpressing head-and-neck cancer models to platinum toxicity

2019 ◽  
Vol 476 (24) ◽  
pp. 3705-3719 ◽  
Author(s):  
Avani Vyas ◽  
Umamaheswar Duvvuri ◽  
Kirill Kiselyov
Keyword(s):  
Oxidative Stress ◽  
Head And Neck ◽  
Transcriptional Activation ◽  
Platinum Resistance ◽  
Mrna Levels ◽  
Strong Positive Correlation ◽  
Platinum Compounds ◽  
Copper Chelation ◽  
Novel Approach ◽  
Cancer Models

Platinum-containing drugs such as cisplatin and carboplatin are routinely used for the treatment of many solid tumors including squamous cell carcinoma of the head and neck (SCCHN). However, SCCHN resistance to platinum compounds is well documented. The resistance to platinum has been linked to the activity of divalent transporter ATP7B, which pumps platinum from the cytoplasm into lysosomes, decreasing its concentration in the cytoplasm. Several cancer models show increased expression of ATP7B; however, the reason for such an increase is not known. Here we show a strong positive correlation between mRNA levels of TMEM16A and ATP7B in human SCCHN tumors. TMEM16A overexpression and depletion in SCCHN cell lines caused parallel changes in the ATP7B mRNA levels. The ATP7B increase in TMEM16A-overexpressing cells was reversed by suppression of NADPH oxidase 2 (NOX2), by the antioxidant N-Acetyl-Cysteine (NAC) and by copper chelation using cuprizone and bathocuproine sulphonate (BCS). Pretreatment with either chelator significantly increased cisplatin's sensitivity, particularly in the context of TMEM16A overexpression. We propose that increased oxidative stress in TMEM16A-overexpressing cells liberates the chelated copper in the cytoplasm, leading to the transcriptional activation of ATP7B expression. This, in turn, decreases the efficacy of platinum compounds by promoting their vesicular sequestration. We think that such a new explanation of the mechanism of SCCHN tumors’ platinum resistance identifies novel approach to treating these tumors.

Collecting Words: A Clinical Example of a Morphology-Focused Orthographic Intervention

2020 ◽  
Vol 51 (3) ◽  
pp. 544-560 ◽  
Author(s):  
Kimberly A. Murphy ◽  
Emily A. Diehm
Keyword(s):  
Written Language ◽  
Morphological Knowledge ◽  
English Orthography ◽  
Word Level ◽  
Novel Approach ◽  
Language Pathology ◽  
The One ◽  
Critical Intervention ◽  
Reading And Spelling ◽  
Reading And Spelling Difficulties

Purpose Morphological interventions promote gains in morphological knowledge and in other oral and written language skills (e.g., phonological awareness, vocabulary, reading, and spelling), yet we have a limited understanding of critical intervention features. In this clinical focus article, we describe a relatively novel approach to teaching morphology that considers its role as the key organizing principle of English orthography. We also present a clinical example of such an intervention delivered during a summer camp at a university speech and hearing clinic. Method Graduate speech-language pathology students provided a 6-week morphology-focused orthographic intervention to children in first through fourth grade ( n = 10) who demonstrated word-level reading and spelling difficulties. The intervention focused children's attention on morphological families, teaching how morphology is interrelated with phonology and etymology in English orthography. Results Comparing pre- and posttest scores, children demonstrated improvement in reading and/or spelling abilities, with the largest gains observed in spelling affixes within polymorphemic words. Children and their caregivers reacted positively to the intervention. Therefore, data from the camp offer preliminary support for teaching morphology within the context of written words, and the intervention appears to be a feasible approach for simultaneously increasing morphological knowledge, reading, and spelling. Conclusion Children with word-level reading and spelling difficulties may benefit from a morphology-focused orthographic intervention, such as the one described here. Research on the approach is warranted, and clinicians are encouraged to explore its possible effectiveness in their practice. Supplemental Material https://doi.org/10.23641/asha.12290687

Abstract #709: E-Consults: A Novel Approach to Increase Access to Subspecialty Care in Endocrinology

2015 ◽  
Vol 21 ◽  
pp. 128
Author(s):  
Kaniksha Desai ◽  
Halis Akturk ◽  
Ana Maria Chindris ◽  
Shon Meek ◽  
Robert Smallridge ◽  
...  
Keyword(s):  
Novel Approach
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