Ultrastructural localization of Ca2+-binding sites in the middle ear mucosa of the rat

1990 ◽  
Vol 247 (3) ◽  
Author(s):  
M.C. Karatay ◽  
W. Mann ◽  
U.-R. Heinrich
Keyword(s):  
Middle Ear ◽  
Binding Sites ◽  
Ultrastructural Localization ◽  
Middle Ear Mucosa

Are mucin genes yet to be cloned expressed by human middle ear mucosa?

1998 ◽  
Vol 23 (3) ◽  
pp. 265-265 ◽  
Author(s):  
Hutton ◽  
Birchall ◽  
French ◽  
Kubba ◽  
Severn ◽  
...  
Keyword(s):  
Middle Ear ◽  
Middle Ear Mucosa ◽  
Mucin Genes ◽  
Human Middle Ear

scholarly journals Immunohistochemical and qPCR Detection of SARS-CoV-2 in the Human Middle Ear Versus the Nasal Cavity: Case Series

2021 ◽  
Author(s):  
Arwa Kurabi ◽  
Kwang Pak ◽  
Adam S. DeConde ◽  
Allen F. Ryan ◽  
Carol H. Yan
Keyword(s):  
Nasal Cavity ◽  
Middle Ear ◽  
Viral Infections ◽  
Case Series ◽  
Middle Ear Mucosa ◽  
Viral Receptor ◽  
Tissue Samples ◽  
Angiotensin Converting Enzyme 2 ◽  
Nasal Tissue ◽  
Human Middle Ear

AbstractViral infections have already been implicated with otitis media and sudden sensorineural hearing loss. However, the pathophysiology of COVID-19 as it relates to otologic disorders is not well-defined. With the spread of SARS-CoV-2, it is important to evaluate its colonization of middle ear mucosa. Middle ear and nasal tissue samples for quantitative RT-PCR and histologic evaluations were obtained from post-mortem COVID-19 patients and non-diseased control patients. Here we present evidence that SARS-CoV-2 colonizes the middle ear epithelium and co-localizes with the primary viral receptor, angiotensin-converting enzyme 2 (ACE2). Both middle ear and nasal epithelial cells show relatively high expression of ACE2, required for SARS-CoV-2 entry. The epithelial cell adhesion molecule (EpCAM) was use as a biomarker of epithelia. Furthermore, we found that the viral load in the middle ear is lower than that present in the nasal cavity.

Atypical Pharyngitis In Suppurative Otitis Media Cases

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P98-P99
Author(s):  
Alaa A Abou-Bieh ◽  
Mona F Salama
Keyword(s):  
Middle Ear ◽  
Causative Organism ◽  
Isolation And Identification ◽  
Middle Ear Mucosa ◽  
Suppurative Otitis Media ◽  
Gram Negative ◽  
Middle Ear Infection ◽  
Gram Negative Organisms ◽  
Micro Organisms ◽  
Middle Ear Cleft

Problem Unexplained persistent or recurrent bacterial pharyngitis in some patients who suffer from infected middle ear cleft. Methods Bacteriological swabs were obtained from both the ears and the pharynx of 37 cases with chronic otorrhea and perforation, whom complain of recurrent or persistent sore-throat. Then isolation and identification of the micro-organisms were done. This included examination of direct Gram stained films and cultures. Isolated Gram negative bacilli were subjected to further identification by the biochemical reactions and antibiotyping. Identical isolates from the same patient (ear and pharyngeal swabs) were subjected to further identification by genotyping using the pulsed field gel electrophoresis technique. Results 6 cases (16%) showed identity in phenotypes and genotypes for ear and pharyngeal samples from the same patient. All pharyngeal isolates were Gram negative organisms. 4 of them were Pseudomonas aeruginosa, 1 was Proteus sp., and 1 was Escherichia coli. All of these 3 species are not known to be among the primary organisms which may cause pharyngitis. Conclusion Bacterial pharyngitis in patients with chronically infected middle ear cleft may be attributed to the same organism invaded the middle ear mucosa. Also this study highlights some organisms as a pharyngeal invaders although they are not among the previously documented causatives of bacterial pharyngitis. But the study do not confirm the method of spread of these organisms and whether this was directly via the eustachian tube. Significance The study correlates the causative organism of the middle ear infection and that infected the pharyngeal mucosa utilizing the advanced bacteriological identification and genotyping techniques.

Histochemical Characteristics of Normal Middle Ear Mucosa

1972 ◽  
Vol 74 (1-6) ◽  
pp. 45-56 ◽  
Author(s):  
F. Hiraide ◽  
M. M. Paparella
Keyword(s):  
Middle Ear ◽  
Middle Ear Mucosa

Neural Control of the Middle Ear Mucosa

1988 ◽  
Vol 105 (sup457) ◽  
pp. 159-163
Author(s):  
Jukka Ylikoski ◽  
Igor Mrena ◽  
Pertti Panula ◽  
Olli Häppölä ◽  
Heikki Päivärinta
Keyword(s):  
Middle Ear ◽  
Neural Control ◽  
Middle Ear Mucosa

scholarly journals A child’s mysterious ear

2021 ◽  
Vol 7 (9) ◽  
pp. 1555
Author(s):  
Preeti Shetti ◽  
Shivani Gupta ◽  
Paramita Debnath
Keyword(s):  
Foreign Body ◽  
Middle Ear ◽  
External Auditory Canal ◽  
Pediatric Patients ◽  
Middle Ear Mucosa ◽  
Polypoidal Mass

<p>Foreign body in ear is an emergency encountered by an otolaryngologist and if not removed it can lead to serious complications. Most commonly foreign body in ear is lodged in external auditory canal while it’s rare to find it in middle ear. We report a case of foreign body in the middle ear in a 3-year-old child who presented to us with chronic discharging ear who was then suspected to be unsafe ear and so was taken up for exploration under microscope. A pink polypoidal mass arising from middle ear mucosa was found and following its removal- to our surprise; a blackish rubbery debris filling the middle ear cavity and attic area along with embedded foreign body was extracted. We conclude that pediatric patients with chronic ear discharge not responding to antibiotics should raise a suspicion of FB in the middle ear and explored timely.</p>

Sign in / Sign up

Export Citation Format

Share Document