Cytomorphological, cytogenetic, and molecular biological characterization of four new human renal carcinoma cell lines of the clear cell type

1994 ◽  
Vol 424 (4) ◽  
Author(s):  
C.D. Gerharz ◽  
U. Ramp ◽  
N. Marx ◽  
H.E. Gabbert ◽  
J. Olert ◽  
...  
1997 ◽  
Vol 157 (6) ◽  
pp. 2345-2350 ◽  
Author(s):  
Uwe Ramp ◽  
Kai Jaquet ◽  
Petra Reinecke ◽  
Cordula Schardt ◽  
Ulrike Friebe ◽  
...  

1986 ◽  
Vol 126 (3) ◽  
pp. 435-443 ◽  
Author(s):  
Norman F. Nelson ◽  
Witold Cieplak ◽  
Stephen C. Dacus ◽  
Morton D. Prager

2013 ◽  
Vol 28 (3) ◽  
pp. 267-273 ◽  
Author(s):  
Marica Gemei ◽  
Rosa Di Noto ◽  
Peppino Mirabelli ◽  
Luigi Del Vecchio

In colorectal cancer, CD133+ cells from fresh biopsies proved to be more tumorigenic than their CD133– counterparts. Nevertheless, the function of CD133 protein in tumorigenic cells seems only marginal. Moreover, CD133 expression alone is insufficient to isolate true cancer stem cells, since only 1 out of 262 CD133+ cells actually displays stem-cell capacity. Thus, new markers for colorectal cancer stem cells are needed. Here, we show the extensive characterization of CD133+ cells in 5 different colon carcinoma continuous cell lines (HT29, HCT116, Caco2, GEO and LS174T), each representing a different maturation level of colorectal cancer cells. Markers associated with stemness, tumorigenesis and metastatic potential were selected. We identified 6 molecules consistently present on CD133+ cells: CD9, CD29, CD49b, CD59, CD151, and CD326. By contrast, CD24, CD26, CD54, CD66c, CD81, CD90, CD99, CD112, CD164, CD166, and CD200 showed a discontinuous behavior, which led us to identify cell type-specific surface antigen mosaics. Finally, some antigens, e.g. CD227, indicated the possibility of classifying the CD133+ cells into 2 subsets likely exhibiting specific features. This study reports, for the first time, an extended characterization of the CD133+ cells in colon carcinoma cell lines and provides a “dictionary” of antigens to be used in colorectal cancer research.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Javier Sevilla-Montero ◽  
Raquel Bienes-Martínez ◽  
David Labrousse-Arias ◽  
Esther Fuertes-Yebra ◽  
Ángel Ordóñez ◽  
...  

Tumor Biology ◽  
2009 ◽  
Vol 30 (5-6) ◽  
pp. 249-256 ◽  
Author(s):  
Izumi Matsumoto ◽  
Mami Kouchi ◽  
Kazuo Okimoto ◽  
Kazuyasu Kijima ◽  
Tadayoshi Ueda ◽  
...  

1984 ◽  
Vol 2 (2) ◽  
pp. 146-155 ◽  
Author(s):  
K. H. Kurth ◽  
J. W. van Dongen ◽  
J. C. Romijn ◽  
M. M. L. Lieber ◽  
F. H. Schröder

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