In vitro cytotoxic activity of lithotripter shock waves combined with Adriamycin or with cisplatin on L1210 mouse leukemia cells

1989 ◽  
Vol 115 (3) ◽  
pp. 229-234 ◽  
Author(s):  
Alexander Wilmer ◽  
Stefan Gambihler ◽  
Michael Delius ◽  
Walter Brendel
Keyword(s):  
Shock Waves ◽  
Cytotoxic Activity ◽  
Leukemia Cells ◽  
Mouse Leukemia ◽  
L1210 Mouse Leukemia

Growth of L1210 mouse leukemia cells in vitro

1966 ◽  
Vol 42 (1) ◽  
pp. 157-170 ◽  
Author(s):  
Dorris J. Hutchison ◽  
O.L. Ittensohn ◽  
Mariann R. Bjerregaard
Keyword(s):  
Leukemia Cells ◽  
Mouse Leukemia ◽  
L1210 Mouse Leukemia

Permeabilization of the plasma membrane of L1210 mouse leukemia cells using lithotripter shock waves

1994 ◽  
Vol 141 (3) ◽  
Author(s):  
S. Gambihler ◽  
M. Delhis ◽  
J.W. Ellwart
Keyword(s):  
Plasma Membrane ◽  
Shock Waves ◽  
Leukemia Cells ◽  
Mouse Leukemia ◽  
L1210 Mouse Leukemia

scholarly journals An early enlargement of the putrescine pool is required for growth in L1210 mouse leukemia cells under hypoosmotic stress.

1991 ◽  
Vol 266 (10) ◽  
pp. 6142-6151
Author(s):  
R Poulin ◽  
R S Wechter ◽  
A E Pegg
Keyword(s):  
Leukemia Cells ◽  
Mouse Leukemia ◽  
Hypoosmotic Stress ◽  
L1210 Mouse Leukemia

Augmentation of Hydroxyurea Cytotoxicity by Sintamil in Human Chronic Myeloid Leukemia Cells

1986 ◽  
Vol 72 (5) ◽  
pp. 507-510
Author(s):  
Seema G. Pradhan ◽  
Manik P. Chitnis ◽  
Vathsala S. Basrur ◽  
K. Satyamoorthy ◽  
Suresh H. Advani
Keyword(s):  
Chronic Myeloid Leukemia ◽  
Nucleic Acids ◽  
Cytotoxic Activity ◽  
Exposure Time ◽  
Myeloid Leukemia ◽  
Exposure Dose ◽  
Leukemia Cells ◽  
Vitro Effect

The in vitro effect of sintamil, as a modulator alone and in combination with hydroxyurea (HU), on cytotoxicity was studied in 16 cases of human chronic myeloid leukemia (CML). We investigated the cytotoxicity of the drugs as a function of the exposure dose (HU, 10−4 M; sintamil, 10 μg/ml) and the exposure time (1 h) to the agent. Cytotoxicity was evaluated as the inhibition of incorporation of [3H-methyl]thymidine in the nucleic acids of CML cells. Cytotoxicity of HU was greatly enhanced (P < 0.001) by 1 h exposure of the CML cells to sintamil. The present data indicate that sintamil potentiates the cytotoxic activity of HU in CML cells.

scholarly journals New Humulenes from Hyptis incana (Labiatae)

2013 ◽  
Vol 8 (12) ◽  
pp. 1934578X1300801
Author(s):  
Mitsuru Satoh ◽  
Yoshio Satoh ◽  
Yasuhiro Anzai ◽  
Daisuke Ajisawa ◽  
Keiichi Matsuzaki ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Inhibitory Activity ◽  
Leukemia Cells ◽  
Moderate Activity ◽  
Mouse Leukemia ◽  
Aerial Parts ◽  
Growth Inhibitory ◽  
Growth Inhibitory Activity ◽  
Potent Growth

Two new humulene-type sesquiterpenes, named hyptishumulene I (1) and II (2), have been isolated, together with eight known compounds, a humulene-type sesquiterpene (3), a monoterpene (4) and six abietane-type diterpenoids (5–10) from the aerial parts of Hyptis incana (Labiatae). The cytotoxic activity of the isolated compounds against mouse leukemia cells (L1210) was examined. The abietane-type diterpenoids (5–10) showed rather potent growth inhibitory activity (IC50<15 μM), while the new humulene-type compounds (1 and 2) exhibited moderate activity (IC50>50 μM).

Suppression of P-glycoprotein expression by antipsychotics trifluoperazine in adriamycin-resistant L1210 mouse leukemia cells

2006 ◽  
Vol 28 (4) ◽  
pp. 300-306 ◽  
Author(s):  
Soon Young Shin ◽  
Byeong Hyeok Choi ◽  
Jae-Ryong Kim ◽  
Jung-Hye Kim ◽  
Young Han Lee
Keyword(s):  
Leukemia Cells ◽  
Mouse Leukemia ◽  
P Glycoprotein ◽  
L1210 Mouse Leukemia

Transport of folate compounds, pterins and adenine in L1210 mouse leukemia cells

1982 ◽  
Vol 20 ◽  
pp. 389-408 ◽  
Author(s):  
F.M. Huennekens ◽  
M.R. Suresh ◽  
K.S. Vitols ◽  
G.B. Henderson
Keyword(s):  
Leukemia Cells ◽  
Mouse Leukemia ◽  
L1210 Mouse Leukemia
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