A comparative study of d- and l-amphetamine on the open field performance of rats

1974 ◽  
Vol 39 (1) ◽  
pp. 67-70 ◽  
Author(s):  
P. C. Dandiya ◽  
S. K. Kulkarni
Keyword(s):  
Comparative Study ◽  
Open Field ◽  
Field Performance

Effects of 8-OH-DPAT on open field performance of young and aged rats prenatally exposed to diazepam: a tool to reveal 5-HT1A receptor function

2003 ◽  
Vol 13 (3) ◽  
pp. 209-217 ◽  
Author(s):  
C Cannizzaro ◽  
M Martire ◽  
E Cannizzaro ◽  
R Monastero ◽  
M Gagliano ◽  
...  
Keyword(s):  
Open Field ◽  
Field Performance ◽  
Aged Rats ◽  
Receptor Function ◽  
Prenatally Exposed

Chronic Lead Exposure of Rats: Open-Field Performance

1982 ◽  
Vol 55 (2) ◽  
pp. 487-490 ◽  
Author(s):  
Charles R. Geist ◽  
Jeffrey E. Praed
Keyword(s):  
Drinking Water ◽  
Weight Gain ◽  
Open Field ◽  
Lead Exposure ◽  
Lead Acetate ◽  
Field Performance ◽  
Postnatal Exposure ◽  
Chronic Lead Exposure ◽  
Prenatal Lead Exposure ◽  
Acetate Form

Three groups of male hooded rats were chronically exposed to lead in the acetate form prenatally, as well as postnatally via the dam's milk and in the drinking water, at concentrations of 0 ppm, 19 ppm, and 38 ppm for 35 days. No significant differences were found in weight gain, although significant increases in food consumption were noted in animals receiving 19 ppm lead acetate and increased ingestion of lead acetate in animals receiving 19 ppm and 38 ppm. When subjects were tested in an open-field task, no significant differences were found in emotionality, the number of squares traversed, frequency and duration of rearing, or in frequency of grooming. However, subjects receiving 38 ppm lead displayed a significant reduction in duration of grooming when compared to animals receiving either 19 ppm or 0 ppm. The results suggest that prenatal lead exposure, followed by postnatal exposure, may affect some elements of activity, while having little effect on others.

Lead and spatial vs. cued open field performance

2002 ◽  
Vol 24 (4) ◽  
pp. 551-557 ◽  
Author(s):  
Juan A. Salinas ◽  
Nicole C. Huff
Keyword(s):  
Open Field ◽  
Field Performance

Effects of LSD on open field performance in rats

1969 ◽  
Vol 15 (4) ◽  
pp. 333-340 ◽  
Author(s):  
P. C. Dandiya ◽  
B. D. Gupta ◽  
M. L. Gupta ◽  
S. K. Patni
Keyword(s):  
Open Field ◽  
Field Performance

Sex differences in acetaldehyde on body temperature and open-field performance in the rat

1987 ◽  
Vol 19 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Wendy D. Myers ◽  
Stephen Gibson ◽  
Kim T. Ng ◽  
George Singer
Keyword(s):  
Sex Differences ◽  
Body Temperature ◽  
Open Field ◽  
Field Performance

The contribution of mild thiamine deficiency and ethanol consumption to central cholinergic parameter dysfunction and rats' open-field performance impairment

2001 ◽  
Vol 70 (2-3) ◽  
pp. 227-235 ◽  
Author(s):  
Rita G.W. Pires ◽  
Silvia R.C. Pereira ◽  
José Eymard H. Pittella ◽  
Glaura C. Franco ◽  
Carmencita L.M. Ferreira ◽  
...  
Keyword(s):  
Open Field ◽  
Thiamine Deficiency ◽  
Field Performance ◽  
Ethanol Consumption ◽  
Performance Impairment

Two independent behavioral dimensions in open-field performance.

1967 ◽  
Vol 63 (3) ◽  
pp. 500-504 ◽  
Author(s):  
Arthur E. Whimbey ◽  
Victor H. Denenberg
Keyword(s):  
Open Field ◽  
Field Performance

scholarly journals Field performance analysis of IEEE 802.15.4 XBee for open field and urban environment applications in Smart Districts

2017 ◽  
Vol 122 ◽  
pp. 673-678 ◽  
Author(s):  
Pawel Rycerski ◽  
Luis M. Candanedo Ibarra ◽  
Fivos Galatoulas ◽  
Konstantinos N. Genikomsakis, Ali Bagheri ◽  
Christos S. Ioakimidis
Keyword(s):  
Performance Analysis ◽  
Urban Environment ◽  
Open Field ◽  
Ieee 802.15.4 ◽  
Field Performance

scholarly journals Severity assessment in mice subjected to carbon tetrachloride

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Lisa Ernst ◽  
Leonie Zieglowski ◽  
Mareike Schulz ◽  
Michaela Moss ◽  
Marco Meyer ◽  
...  
Keyword(s):  
Carbon Tetrachloride ◽  
Open Field ◽  
Field Test ◽  
Open Field Test ◽  
Field Performance ◽  
Principal Component ◽  
Laboratory Animals ◽  
Severity Assessment ◽  
Behavioral Tests ◽  
Significant Group

Abstract The Directive 2010/63 EU requires classifying burden and severity in all procedures using laboratory animals. This study evaluated the severity of liver fibrosis induction by intraperitoneal carbon tetrachloride (CCl4) injections in mice. 29 male C57BL/6N mice were treated three times per week for 4 weeks with an intraperitoneal injection (50 µl) of either 0.6 ml/kg body weight CCl4-vehicle solution, germ oil (vehicle-control) or handling only. Severity assessment was performed using serum analysis, behavioral tests (open field test, rotarod, burrowing and nesting behavior), fecal corticosterone metabolite (FCM) measurement, and survival. The most significant group differences were noticed in the second week of treatment when the highest AST (1463 ± 1404 vs. 123.8 ± 93 U/L, p < 0.0001) and nesting values were measured. In addition, respective animals showed lower moving distances (4622 ± 1577 vs. 6157 ± 2060 cm, p < 0.01) and velocity in the Open field, identified as main factors in principal component analysis (PCA). Overall, a 50% survival rate was observed within the treatment group, in which the open field performance was a good tracer parameter for survival. In summary, this study demonstrates the feasibility of assessing severity in mice using behavioral tests and highlight the open field test as a possible threshold parameter for risk assessment of mortality.

Sign in / Sign up

Export Citation Format

Share Document