Studies on experimental malignant nerve sheath tumors maintained in tissue and organ culture systems II. Electron microscopy observations

1976 ◽  
Vol 34 (4) ◽  
pp. 293-310 ◽  
Author(s):  
Frances K. Conley ◽  
Lucien J. Rubinstein ◽  
Alexander M. Spence
1976 ◽  
Vol 35 (1) ◽  
pp. 27-45 ◽  
Author(s):  
Alexander M. Spence ◽  
Lucien J. Rubinstein ◽  
Frances K. Conley ◽  
Mary M. Herman

1976 ◽  
Vol 35 (1) ◽  
pp. 13-25 ◽  
Author(s):  
Bruce C. Horten ◽  
Stephen R. Montague

1990 ◽  
Vol 102 (3) ◽  
pp. 257-263 ◽  
Author(s):  
Robert P. Hillstrom ◽  
Richard J. Zarbo ◽  
John R. Jacobs

Author(s):  
Brian Anderson ◽  
David M. Robertson

SummaryThis case report describes a melanin-containing neurofibroma involving a spinal nerve root. Electron microscopy of the tumor shows that neoplastic Schwann cells are capable of melanogene-sis. Although this capability is suggested in the literature, few reports provide ultra-structural confirmation.The likely identity between reported “cellular blue nevi of spinal nerve roots” and nerve sheath tumors is discussed. It is possible that pigmented nerve sheath tumors behave more aggressively than nonpigmented ones, although it is debatable.


Author(s):  
A. R. Crooker ◽  
M. C. Myers ◽  
T. L. Beard ◽  
E. S. Graham

Cell culture systems have become increasingly popular as a means of screening toxic agents and studying toxic mechanisms of drugs and other chemicals at the cellular and subcellular levels. These in vitro tests can be conducted rapidly in a broad range of relevant mammalian culture systems; a variety of biological and biochemical cytotoxicity endpoints can be examined. The following study utilized human keratinocytes to evaluate the relative cytotoxicities of nitrofurazone (NF) and silver sulfadiazine (SS), the active ingredients of FURACIN(R) Topical Cream and SILVADENE(R) Cream, respectively. These compounds are anti-infectives used in the treatment of burn patients. Cell ultrastructure and elemental composition were utilized as cytotoxicity endpoints.Normal Human Epidermal Keratinocytes (HK) were prepared from the EpiPackTM culture system (Clonetics Corporation, Boulder, CO). For scanning electron microscopy (SEM) and transmission electron microscopy (TEM), cells were seeded on sterile 35 mm Falcon plastic dishes; for elemental microanalysis, cells were plated on polished pyrolytic carbon discs (E. Fullam, Latham, NY) placed in the culture dishes.


2016 ◽  
Vol 77 (S 01) ◽  
Author(s):  
Matthew Carlson ◽  
Jeffrey Jacob ◽  
Elizabeth Habermann ◽  
Amy Wagie ◽  
Aditya Raghunathan ◽  
...  

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