Role of ethanolamine, phosphoethanolamine, and phosphatidylethanolamine in oxidative phosphorylation of albino rat brain mitochondria

1975 ◽  
Vol 80 (4) ◽  
pp. 1195-1196
Author(s):  
K. G. Karagezyan ◽  
L. M. Ovsepyan
Keyword(s):  
Oxidative Phosphorylation ◽  
Rat Brain ◽  
Brain Mitochondria ◽  
Albino Rat ◽  
Rat Brain Mitochondria

scholarly journals The role of ADP in the modulation of the calcium-efflux pathway in rat brain mitochondria

1985 ◽  
Vol 225 (1) ◽  
pp. 41-49 ◽  
Author(s):  
J Vitorica ◽  
J Satrústegui
Keyword(s):  
Rat Brain ◽  
Binding Sites ◽  
Tricarboxylic Acid Cycle ◽  
Brain Mitochondria ◽  
Ruthenium Red ◽  
Calcium Efflux ◽  
Rat Brain Mitochondria ◽  
Pi Complex ◽  
Efflux Pathway

The role of ADP in the regulation of Ca2+ efflux in rat brain mitochondria was investigated. ADP was shown to inhibit Ruthenium-Red-insensitive H+- and Na+-dependent Ca2+-efflux rates if Pi was present, but had no effect in the absence of Pi. The primary effect of ADP is an inhibition of Pi efflux, and therefore it allows the formation of a matrix Ca2+-Pi complex at concentrations above 0.2 mM-Pi and 25 nmol of Ca2+/mg of protein, which maintains a constant free matrix Ca2+ concentration. ADP inhibition of Pi and Ca2+ efflux is nucleotide-specific, since in the presence of oligomycin and an inhibitor of adenylate kinase ATP does not substitute for ADP, is dependent on the amount of ADP present, and requires ADP concentrations in excess of the concentrations of translocase binding sites. Brain mitochondria incubated with 0.2 mM-Pi and ADP showed Ca2+-efflux rates dependent on Ca2+ loads at Ca2+ concentrations below those required for the formation of a Pi-Ca2+ complex, and behaved as perfect cytosolic buffers exclusively at high Ca2+ loads. The possible role of brain mitochondrial Ca2+ in the regulation of the tricarboxylic acid-cycle enzymes and in buffering cytosolic Ca2+ is discussed.

Functional impact of PTP1B-mediated Src regulation on oxidative phosphorylation in rat brain mitochondria

2010 ◽  
Vol 68 (15) ◽  
pp. 2603-2613 ◽  
Author(s):  
Etienne Hébert Chatelain ◽  
Jean-William Dupuy ◽  
Thierry Letellier ◽  
Jeanne Dachary-Prigent
Keyword(s):  
Oxidative Phosphorylation ◽  
Rat Brain ◽  
Brain Mitochondria ◽  
Functional Impact ◽  
Rat Brain Mitochondria

Effects of triiodothyronine on oxidative phosphorylation in immature rat brain mitochondria

Neurology ◽  
1977 ◽  
Vol 27 (1) ◽  
pp. 90-90 ◽  
Author(s):  
D. HOLTZMAN ◽  
C. L. MOORE
Keyword(s):  
Oxidative Phosphorylation ◽  
Rat Brain ◽  
Brain Mitochondria ◽  
Immature Rat ◽  
Rat Brain Mitochondria

Effects of chlordiazepoxide and diazepam on respiration and oxidative phosphorylation in rat brain mitochondria

1971 ◽  
Vol 20 (8) ◽  
pp. 1883-1887 ◽  
Author(s):  
Leon F. Davis ◽  
Edward E. Gatz ◽  
John R. Jones
Keyword(s):  
Oxidative Phosphorylation ◽  
Rat Brain ◽  
Brain Mitochondria ◽  
Rat Brain Mitochondria

STUDIES OF FATTY ACID OXIDATION: 5. THE EFFECT OF DECANOIC ACID ON OXIDATIVE PHOSPHORYLATION

1956 ◽  
Vol 34 (1) ◽  
pp. 1227-1232 ◽  
Author(s):  
P. G. Scholefield
Keyword(s):  
Fatty Acid ◽  
Oxidative Phosphorylation ◽  
Rat Brain ◽  
Fatty Acid Oxidation ◽  
Rat Kidney ◽  
Atp Synthesis ◽  
Decanoic Acid ◽  
Brain Mitochondria ◽  
Acid Oxidation ◽  
Rat Brain Mitochondria

The effects of potassium decanoate on the phosphorylation associated with the oxidation of pyruvate by rat-kidney and rat-brain mitochondria have been investigated. The suggestion that these two processes may be uncoupled from each other in the presence of decanoate has been confirmed. Further, it has been shown that the decanoate-insensitive oxidation of pyruvate by rat-brain mitochondria, occurring in the absence of such stimulating agents as fumarate, is not associated with ATP synthesis. The fumarate-stimulated oxidation of pyruvate by rat-brain mitochondria, which is inhibited by decanoate, is associated with a phosphorylation process which is uncoupled by decanoate. When pyruvate oxidation by rat-kidney or by rat-brain mitochondria is uncoupled from phosphorylation, the extent of uncoupling is proportional to the amount of decanoate added.

Low glucocorticoid concentrations decrease oxidative phosphorylation of isolated rat brain mitochondria: an additional effect of dexamethasone

2000 ◽  
Vol 14 (5) ◽  
pp. 493-500 ◽  
Author(s):  
Christophe Morin ◽  
Roland Zini ◽  
Nicolas Simon ◽  
Peggy Charbonnier ◽  
Jean-Paul Tillement ◽  
...  
Keyword(s):  
Oxidative Phosphorylation ◽  
Rat Brain ◽  
Brain Mitochondria ◽  
Rat Brain Mitochondria ◽  
Isolated Rat

The role of hydroperoxides as calcium release agents in rat brain mitochondria

1984 ◽  
Vol 233 (2) ◽  
pp. 736-740 ◽  
Author(s):  
Jorgina Satrustegui ◽  
Christoph Richter
Keyword(s):  
Rat Brain ◽  
Calcium Release ◽  
Brain Mitochondria ◽  
Rat Brain Mitochondria

Circadian Rhythms of Oxidative Phosphorylation: Effects of Rotenone and Melatonin on Isolated Rat Brain Mitochondria

2003 ◽  
Vol 20 (3) ◽  
pp. 451-461 ◽  
Author(s):  
Nicolas Simon ◽  
Kassim Papa ◽  
Johanna Vidal ◽  
Audrey Boulamery ◽  
Bernard Bruguerolle
Keyword(s):  
Circadian Rhythms ◽  
Oxidative Phosphorylation ◽  
Rat Brain ◽  
Brain Mitochondria ◽  
Rat Brain Mitochondria ◽  
Isolated Rat
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