Time course of brain dehydrogenase and GABA transaminase activity during metrazol kindling

1986 ◽  
Vol 101 (1) ◽  
pp. 16-18
Author(s):  
G. N. Kryzhanovskii ◽  
I. N. Moiseev ◽  
A. A. Shandra ◽  
R. F. Makul'kin ◽  
L. S. Godlevskii
Keyword(s):  
Time Course ◽  
Transaminase Activity ◽  
Gaba Transaminase ◽  
Metrazol Kindling

In vitro brain GABA-transaminase activity of 1-(4-acetylphenyl)-3-aryloxypyrrolidine-2,5-dione derivatives

2013 ◽  
Vol 6 (4) ◽  
pp. 442-446 ◽  
Author(s):  
Jigarkumar R. Patel ◽  
Bharat Z. Dholakiya ◽  
Nibha Mishra
Keyword(s):  
Transaminase Activity ◽  
Gaba Transaminase ◽  
Brain Gaba

Interleukin 1β and GABA-transaminase activity in rat thymus

2000 ◽  
Vol 22 (9) ◽  
pp. 719-728 ◽  
Author(s):  
D. Cavallotti ◽  
M. Artico ◽  
C. Cavallotti ◽  
S. De Santis ◽  
F.Tranquilli Leali
Keyword(s):  
Interleukin 1Β ◽  
Transaminase Activity ◽  
Gaba Transaminase

Reduced GABA transaminase activity in the Huntington's disease putamen

1984 ◽  
Vol 48 (3) ◽  
pp. 339-342 ◽  
Author(s):  
C.J. Carter
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Transaminase Activity ◽  
Gaba Transaminase

scholarly journals Role of nitric oxide synthase on brain GABA transaminase activity and GABA levels

2018 ◽  
Vol 68 (3) ◽  
pp. 349-359 ◽  
Author(s):  
Lourdes A. Vega Rasgado ◽  
Guillermo Ceballos Reyes ◽  
Fernando Vega Díaz
Keyword(s):  
Nitric Oxide ◽  
Ex Vivo ◽  
Transaminase Activity ◽  
Gaba Transaminase ◽  
Neuronal Nos ◽  
New Generation ◽  
Oxide Synthase ◽  
Brain Gaba

Abstract In an attempt to clarify the controversial role of nitric oxide (NO) in seizures, the effects of NO on brain GABA transaminase (GABA-T) activity and GABA levels were investigated. To this aim, the effects of the substrate (l-arginine) and inhibitors (Nω-nitro-l-arginine methyl ester, 7-nitroindazole) of NO synthase (NOS) on GABA-T activity and GABA levels in vitro and ex vivo were analyzed. In vitro NO diminished GABA-T activity and increased GABA. Ex vivo NO modified GABA-T activity and GABA levels biphasically. Inhibition of endothelial and neuronal NOS (eNOS and nNOS) had opposite effects on GABA-T activity and GABA levels, even during seizures induced by pentylenetetrazole. Different effects of NO on GABA-T activity and on GABA levels, depending on the NOS isoform involved, may explain its contradictory role in seizures, the endothelial NOS acting as an anticonvulsant and the neuronal NOS as a proconvulsant. nNOS inhibitors may represent a new generation of antiepileptics.

GABA-transaminase activity in rat and human brain: regional, age and sex-related differences

1991 ◽  
Vol 84 (1-2) ◽  
pp. 95-102 ◽  
Author(s):  
F. Sherif ◽  
L. Eriksson ◽  
L. Oreland
Keyword(s):  
Human Brain ◽  
Transaminase Activity ◽  
Gaba Transaminase ◽  
Age And Sex

Effects of the antidepressant/antipanic drug phenelzine on GABA concentrations and GABA-transaminase activity in rat brain

1992 ◽  
Vol 43 (11) ◽  
pp. 2486-2489 ◽  
Author(s):  
David J. McManus ◽  
Glen B. Baker ◽  
Ian L. Martin ◽  
Andrew J. Greenshaw ◽  
Kevin F. McKenna
Keyword(s):  
Rat Brain ◽  
Transaminase Activity ◽  
Gaba Transaminase

scholarly journals Segmental distribution and gestational changes of GABA-transaminase activity in the rat oviduct

Reproduction ◽  
1986 ◽  
Vol 78 (2) ◽  
pp. 593-599 ◽  
Author(s):  
F. Amenta ◽  
C. Cavallotti ◽  
M. C. Mione ◽  
S. L. Erdo
Keyword(s):  
Transaminase Activity ◽  
Gaba Transaminase

β-hydroxybutyrate alters GABA-transaminase activity in cultured astrocytes

2009 ◽  
Vol 1268 ◽  
pp. 17-23 ◽  
Author(s):  
Yuka Suzuki ◽  
Hisaaki Takahashi ◽  
Mitsumasa Fukuda ◽  
Hitomi Hino ◽  
Kana Kobayashi ◽  
...  
Keyword(s):  
Transaminase Activity ◽  
Gaba Transaminase ◽  
Cultured Astrocytes
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