Mitochondrial DNA, RNA, and protein synthesis in different regions of developing rat brain

1979 ◽  
Vol 4 (1) ◽  
pp. 37-52 ◽  
Author(s):  
A. M. Giuffrida ◽  
M. N. Gadaleta ◽  
I. Serra ◽  
M. Renis ◽  
E. Geremia ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Protein Synthesis ◽  
Rat Brain ◽  
Rna And Protein Synthesis ◽  
Developing Rat

Mitochondrial DNA, RNA and protein synthesis in normal and hypothyroid developing rat liver

1986 ◽  
Vol 19 (1) ◽  
pp. 43-49 ◽  
Author(s):  
Maria Nicola Gadaleta ◽  
Giulia Rosa Minervini ◽  
Marcella Renis ◽  
Carla De Giorgi ◽  
Angelo Giovine
Keyword(s):  
Mitochondrial Dna ◽  
Protein Synthesis ◽  
Rat Liver ◽  
Rna And Protein Synthesis ◽  
Developing Rat

Regulation of tubulin by triiodothyronine in hypothyroid rat brain

1985 ◽  
Vol 5 (8) ◽  
pp. 643-648 ◽  
Author(s):  
Anjana Mazumder ◽  
Kamal Das ◽  
Pranab K. Sarkar
Keyword(s):  
Protein Synthesis ◽  
Rat Brain ◽  
Brain Maturation ◽  
Normal Brain ◽  
Neonatal Brain ◽  
Organ Cultures ◽  
Postnatal Brain ◽  
Enhanced Sensitivity ◽  
Brain Exposure ◽  
Developing Rat

The effect of T3 (triiodothyronine) on the induction of tubulin in hypothyroid developing rat brain has been examined using organ cultures of brains from late fetal, neonatal and postnatalrats. The neonatal brain displayed maximum sensitivity to T3. Hypothyroidism resulted in a 26% decline in the level of tubulin in the neonatal brain as opposed to a 5–15% decline in the fetal or postnatal brain. Exposure of the hypothyroi d neonatal brain to T3 for 2 h in culture led to a 61% rise in the level of tubulin in contrast to a 41% increase seen in the case of normal brain. Total protein synthesis was not significantly affected. The preferential decline of tubulin in the neonatal hypothyroid brain, its enhanced sensitivity to T3 compared to normal brain, and the coincidence of the period of sensitivity to that of brain maturation indicate that the regulation of the level of tubulin by T3 in the developing brain is a natural ontogenic phenomenon.

scholarly journals Subcellular distribution of taurine and cysteinesulphinate decarboxylase in developing rat brain

1971 ◽  
Vol 122 (5) ◽  
pp. 759-763 ◽  
Author(s):  
H. C. Agrawal ◽  
A. N. Davison ◽  
L. K. Kaczmarek
Keyword(s):  
Amino Acids ◽  
Protein Synthesis ◽  
Rat Brain ◽  
Nerve Ending ◽  
Glutamate Decarboxylase ◽  
Decarboxylase Activity ◽  
Regional Heterogeneity ◽  
Anatomical Distribution ◽  
Developing Rat ◽  
The Brain

The concentration of taurine and the activities of cysteinesulphinate decarboxylase and glutamate decarboxylase have been measured in rat brain. During development, taurine exhibited a decrease in concentration unrelated to the activity of cysteinesulphinate decarboxylase which increased during the same period. The distribution of taurine in subcellular fractions of adult and 7-day-old rat brain was typical of most amino acids, whereas half of the cysteinesulphinate decarboxylase activity was found in the nerve-ending cytoplasm. In anatomical distribution, taurine displayed great regional heterogeneity but both cysteinesulphinate decarboxylase and glutamate decarboxylase were more evenly distributed. Hypertaurinaemia was shown to have no effect on the entry of glycine into the brain or on its utilization in protein synthesis.

RNA and Protein Synthesis in Rat Brain during Exercise

Pharmacology ◽  
1979 ◽  
Vol 19 (1) ◽  
pp. 51-56 ◽  
Author(s):  
Carlo Guarnieri ◽  
Fernando Fussi ◽  
Ottorino Fanelli ◽  
Pierpaola Davalli ◽  
Carlo Clò
Keyword(s):  
Protein Synthesis ◽  
Rat Brain ◽  
Rna And Protein Synthesis
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