Differential effects of metal ions on type a and type B monoamine oxidase activities in rat brain and liver mitochondria

1992 ◽  
Vol 7 (3) ◽  
pp. 139-146 ◽  
Author(s):  
Thomas K. C. Leung ◽  
Louis Lim ◽  
James C. K. Lai
Keyword(s):  
Monoamine Oxidase ◽  
Metal Ions ◽  
Rat Brain ◽  
Type A ◽  
Liver Mitochondria ◽  
Type B ◽  
Differential Effects ◽  
Rat Brain And Liver

Substrate Selectivity of Type A and Type B Monoamine Oxidase in Rat Brain

1980 ◽  
Vol 35 (1) ◽  
pp. 109-115 ◽  
Author(s):  
Hiroyasu Kinemuchi ◽  
Yoshiko Wakui ◽  
Kazuya Kamijo
Keyword(s):  
Monoamine Oxidase ◽  
Rat Brain ◽  
Type A ◽  
Substrate Selectivity ◽  
Type B

Dehydroepiandrosterone Treatment Alters Lipid/Phospholipid Profiles of Rat Brain and Liver Mitochondria

2006 ◽  
Vol 3 (4) ◽  
pp. 273-279 ◽  
Author(s):  
Surendra Katyare ◽  
Hiren Modi ◽  
Minal Patel
Keyword(s):  
Rat Brain ◽  
Liver Mitochondria ◽  
Rat Brain And Liver

Gonadal Influences on the Sexual Differentiation of Monoamine Oxidase Type A and B Activities in the Rat Brain

1982 ◽  
Vol 37 (3) ◽  
pp. 640-648 ◽  
Author(s):  
A. Vaccari ◽  
A. Caviglia ◽  
A. Sparatore ◽  
R. Biassoni
Keyword(s):  
Monoamine Oxidase ◽  
Rat Brain ◽  
Sexual Differentiation ◽  
Type A

scholarly journals A comparison of the regulation of pyruvate dehydrogenase in mitochondria from rat brain and liver

1975 ◽  
Vol 150 (3) ◽  
pp. 397-403 ◽  
Author(s):  
R Jope ◽  
J P Blass
Keyword(s):  
Rat Brain ◽  
Dehydrogenase Activity ◽  
Pyruvate Dehydrogenase ◽  
Active Form ◽  
Energy Charge ◽  
Liver Mitochondria ◽  
Brain Mitochondria ◽  
Ruthenium Red ◽  
Rat Brain And Liver ◽  
Pyruvate Dehydrogenase Phosphatase

The total activity of pyruvate dehydrogenase in mitochondria isolated from rat brain and liver was 53.5 and 14.2nmol/min per mg of protein respectively. Pyruvate dehydrogenase in liver mitochondria incubated for 4 min at 37 degrees C with no additions was 30% in the active form and this activity increased with longer incubations until it was completely in the active form after 20 min. Brain mitochondrial pyruvate dehydrogenase activity was initially high and did not increase with addition of Mg2+ plus Ca2+ or partially purified pyruvate dehydrogenase phosphatase or with longer incubations. The proportion of pyruvate dehydrogenase in the active form in both brain and liver mitochondria changed inversely with changes in mitochondrial energy charge, whereas total pyruvate dehydrogenase did not change. The chelators citrate, isocitrate, EDTA, ethanedioxybis(ethylamine)tetra-acetic acid and Ruthenium Red each lowered pyruvate dehydrogenase activity in brain mitochondria, but only citrate and isocitrate did so in liver mitochondria. These chelators did not affect the energy charge of the mitochondria. Mg2+ plus Ca2+ reversed the pyruvate dehydrogenase inactivation in liver, but not brain, mitochondria. The regulation of the activation-inactivation of pyruvate dehydrogenase in mitochondria from rat brain and liver with respect to energy charge is similar and may be at least partially regulated by this parameter, and the effects of chelators differ in the two types of mitochondria.

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