Somatostatin binding sites in cytosolic fractions of parietal and non-parietal cells from rabbit fundic mucosa
Keyword(s):
Specific binding sites for somatostatin have been found in the cytosolic fractions of both parietal and non-parietal cells from rabbit gastric fundic mucosa. The stoichiometric data suggested the presence of two classes of binding sites in both types of ceils. The number of low-affinity binding sites was significantly higher in parietal cells than in non-parietal cells. The reverse was true for the high-affinity binding sites. However, the affinity of each class of binding sites was similar in the cytosolic fractions of both parietal and non-parietal ceils. It thus appears that low-affinity somatostatin binding sites are mainly located in the parietal ceils whereas the high-affinity sites occur principally in the non-parietal cells.
1986 ◽
Vol 64
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pp. 515-520
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1999 ◽
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pp. G1052-G1058
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2010 ◽
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pp. 1608-1618
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1994 ◽
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pp. 465-474
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1989 ◽
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pp. 961-964
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1983 ◽
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pp. 5344-5347
1990 ◽
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pp. 15564-15571
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1990 ◽
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pp. 1050-1056
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