Synthesis of 11-N-arylaminomethylene derivatives of 8-azasteroies. A new rection of cyclic Schiff's bases

1995 ◽  
Vol 31 (2) ◽  
pp. 235-236
Author(s):  
O. V. Gulyakevich ◽  
A. L. Mikhail'chuk ◽  
A. A. Akhrem
Keyword(s):  
Schiff’S Bases ◽  
Schiff's Bases ◽  
Derivatives Of

scholarly journals Synthesis and Screening of Biologically Active Schiff bases of Benzothiazoles and its Zinc and Lanthanum Metal Complexes

2021 ◽  
Vol 37 (1) ◽  
pp. 187-193
Author(s):  
D. G. Anuse ◽  
V. J. Desale ◽  
B. R. Thorat ◽  
D. D. Anuse ◽  
S. G. Jagadhani ◽  
...  
Keyword(s):  
Metal Complex ◽  
Metal Complexes ◽  
Schiff Bases ◽  
Zinc Chloride ◽  
Biological Activities ◽  
Biologically Active ◽  
Lanthanum Chloride ◽  
Schiff’S Bases ◽  
Schiff's Bases ◽  
Derivatives Of

The substituted 2-Aminobenzothiazole and ethyl 2-(4-formyl-3-hydroxyphenyl)-4-methylthiazole-5-carboxylate in methanol mix together and heat the reaction mixture for overnight, It gives Schiff’s bases (derivatives of substituted aminobenzothiazole) 3. This compound 3 when treated with Zinc Chloride it gives Zinc metal complex of Schiff’s bases 4 and if compound 3 was treated with Lanthanum chloride gives Lanthanum metal complex of Schiff’s bases 5, which shows marked biological activities.

A novel acyl hydrazone schiff’s bases of benzimidazole-2-thiol

2021 ◽  
Vol 10 (4) ◽  
pp. 151-155
Author(s):  
Amir Hassan ◽  
Nawaz Khan
Keyword(s):  
Acetic Acid ◽  
Biological Activities ◽  
Schiff’S Bases ◽  
Cool Water ◽  
Schiff's Bases ◽  
Acyl Hydrazone ◽  
Derivatives Of

A series of novel acyl hydrazone derivatives of benzimidazole-2-thiol were synthesized. The acylhydrazide was condensed with a series of aromatic substituted aldehydes to yield the tetra decylhydrazone Schiff”s bases of benzimidazole-2-thiol. The acylhydrazide was taken in methanol in round bottom flask added 2-3 drops acetic acid and refluxed on hotplate the reaction mixture was monitored with TLC. After completion of reaction the product was precipitated in ice cool water, washed and dried. The synthesized compounds were screened for different biological activities such as antimicrobial, antihistamine, neutropic, analgesic, antiprotozoal, antimalarial, antiallergic, antioxidant, anticonvulsant, anti-tubercular and have shown a good results.

scholarly journals Synthesis, characterization and biological evaluation of Schiff’s bases derivatives as potent antibacterial agents

2017 ◽  
Vol 4 (5) ◽  
pp. 216
Author(s):  
Versha Parcha ◽  
Ankit Kumar ◽  
Babita Mahajan ◽  
Jaswinder Kaur
Keyword(s):  
Antibacterial Effect ◽  
Biological Evaluation ◽  
Spectral Studies ◽  
Schiff’S Bases ◽  
Zone Of Inhibition ◽  
Schiff's Bases ◽  
Almost All ◽  
Derivatives Of ◽  
Antibacterial Potential ◽  
Schiffs Bases

Objective: To design, synthesize and screen biologically newer Substituted Schiff bases by condensing substituted acid hydrazides with various benzaldehydes and explore their antimicrobial potential.Methods: Present study synthesis of various derivatives of Schiffs bases was carried out by: firstly converting substituted acids to acid hydrazides and then to Schiff's bases after condensation with substituted benzaldehyde. Synthesized compounds were characterised on the basis of spectral studies (like UV, IR, and NMR). All the synthesized derivatives were screened further for their antibacterial effect against Salmonella typhimurium, Shigella sonnei, Staphylococcus aureus& Bacillus cereus.Results: From this study it could be observed that schiff’s bases 2-[( aminophenylhydrazinyldene o,m,dinitrobenzoyl] aniline (H) and compound 2-[( aminophenylzinyldene) p amino benzoyl] aniline (I) showed very good zone of inhibition against almost all strains tested for.Conclusions: So further attempts could be made to extend the series and explore their antibacterial potential to achieve hopeful goal.

Green Synthesis, Characterization, DPPH and Ferrous Ion-chelating (FIC) Activity of Tetrakis-Schiff’s Bases of Terephthalaldehyde

2019 ◽  
Vol 16 (3) ◽  
pp. 249-255
Author(s):  
Momin Khan ◽  
Umar Ali ◽  
Anis Ur Rahman ◽  
Muhammad Ibrahim ◽  
Abdul Hameed ◽  
...  
Keyword(s):  
Antioxidant Activities ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Aromatic Aldehydes ◽  
Ferrous Ion ◽  
Future Research ◽  
Scavenging Activity ◽  
Schiff’S Bases ◽  
Schiff's Bases ◽  
Antioxidant Agents

Background: The role of small molecules as antioxidants to prevent the oxidation of other molecules and inhibit them from radical formation is the area of much interest to cure disease especially cancer. Moreover, the antioxidants play important role as stabilizers to prevent oxidation of fuels and lubricants. </P><P> Methods: In the present study, fifteen tetrakis-Schiff’s bases derivatives (1-15) were synthesized and screened for their antioxidant activities. Compounds 1-15 were synthesized by continuous stirring of reaction mixture of 1,4-bis (hydrazonomethyl)benzene (1 mmol) with various substituted aromatic aldehydes (2 mmol) in distilled water using acetic acid as catalyst at room temperature for 2-10 min. </P><P> Results: Our present study showed that all compounds are better ferrous ion-chelating agents except compound 1,4-bis((E)-((E)-(3,4-dimethoxybenzylidene)hydrazono)methyl)benzene (6) (IC50 = 329.26 &#177; 4.75 &#181;M) which has slightly low activity than the standard EDTA (IC50 = 318.40 &#177; 5.53 μM). In addition, DPPH radical scavenging activity of eleven compounds showed higher activity than the standard. However, remaining four compounds showed comparable radical scavenging activity to the standard DPPH (IC50 = 257.77 &#177; 4.60 &#181;M). </P><P> Conclusion: The series of fifteen Schiff’s bases (1-15) were synthesized and evaluated as antioxidants. From both assays, it has been demonstrated that most of the tetrakis-Schiff’s bases have potential to serve as leads for the development of antioxidant agents for future research.

Synthesis of Schiff's bases Derived from 2- Amino - 1,3,4- Thiadiazole and 1,3,4- Oxadiazole with Naphthaldehydes

2006 ◽  
Vol 9 (1) ◽  
pp. 21-28
Author(s):  
Emaad . T. bakir Al-Takrity ◽  
◽  
Ibtisam K. Jassim ◽  
Wissam K. Jassim ◽  
◽  
...  
Keyword(s):  
Schiff’S Bases ◽  
Schiff's Bases

Study of uranium/VI/ collection by two Schiff's bases obtained from chitosan

1987 ◽  
Vol 118 (2) ◽  
pp. 99-109 ◽  
Author(s):  
P. L. Lopez-de-Alba ◽  
B. Urbina ◽  
J. C. Alvarado ◽  
G. A. Andreu ◽  
J. A. Lopez
Keyword(s):  
Schiff’S Bases ◽  
Schiff's Bases

Microwave Assisted Synthesis of Schiff Bases: A Green Approach

2012 ◽  
Vol 10 (1) ◽  
Author(s):  
Mousumi Chakraborty ◽  
Sanjay Baweja ◽  
Sunita Bhagat ◽  
TejpalSingh Chundawat
Keyword(s):  
Microwave Irradiation ◽  
Microwave Power ◽  
Mass Spectra ◽  
Molar Ratio ◽  
Microwave Assisted Synthesis ◽  
Schiff’S Bases ◽  
Microwave Assisted ◽  
Green Approach ◽  
Schiff's Bases ◽  
Effects Of Temperature

Abstract In the present study Schiff’s bases are synthesized by the conventional as well as by microwave irradiation. Excellent yield within short reaction time is obtained using microwave irradiation along with other advantages like mild reaction condition, non-hazardous and safer environmental conditions. The effects of temperature, reactant molar ratio, and microwave power variation on yield are observed. Mathematical model has been developed using matlab software to obtain the yield as a function of microwave power. Kinetic study of the reaction has also been attempted. Schiff’s bases structures are confirmed by IR, 1HNMR, Mass Spectra and elemental analysis.

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