The use of irradiation and fusion gene transfer (IFGT) hybrids to isolate DNA clones from human chromosome region 9q33-q34

1991 ◽  
Vol 17 (5) ◽  
pp. 445-453 ◽  
Author(s):  
Fiorella Florian ◽  
Nick Hornigold ◽  
Darren K. Griffin ◽  
Joy D. Delhanty ◽  
Louise Sefton ◽  
...  
Keyword(s):  
Gene Transfer ◽  
Human Chromosome ◽  
Fusion Gene ◽  
Chromosome Region

EMBRYO MANIPULATION AND GENE TRANSFER IN LIVESTOCK

1985 ◽  
Vol 65 (3) ◽  
pp. 527-538 ◽  
Author(s):  
R. B. CHURCH ◽  
F. J. SCHAUFELE ◽  
K. MECKLING
Keyword(s):  
Gene Transfer ◽  
Genetic Engineering ◽  
Embryo Transfer ◽  
Dna Sequences ◽  
Recombinant Dna ◽  
Fusion Gene ◽  
Bovine Genome ◽  
Monozygotic Twins ◽  
Genetically Engineered ◽  
Livestock Species

In the past few years significant progress has been made in manipulation of reproduction and in development of genetic engineering techniques which can be applied to animal species. Artificial insemination and embryo transfer are now used widely in the livestock industry. The advent of non-surgical embryo collection and transfer, embryo freezing and splitting along with estrus synchronization has allowed the industry to move from the laboratory to the farm. Embryo manipulation now involves embryo splitting to produce monozygotic twins, in vitro fertilization, cross-species fertilization, embryo sexing, and chimeric production of tetraparental animals among others. Advances in recombinant DNA, plasmid construction and embryo manipulation technologies allow the production of genetically engineered animals. The application of recombinant DNA technology involves the isolation and manipulation of desired genes which have potential for significant changes in productivity in genetically engineered livestock. Recombinant DNA constructs involve the coupling of promoter, enhancer, regulatory and structural DNA sequences to form a "fusion gene" which can then be multiplied, purified, assayed and expressed in cell culture prior to being introduced into an animal genome. Such DNA gene constructs are readily available for many human and mouse genes. However, they are not readily available for livestock species because the detailed molecular biology has not yet been established in these species. Gene transfer offers a powerful new tool in animal research. Transfer of genes into the bovine genome has been accomplished. However, successful directed expression of these incorporated genes has not been achieved to date. New combinations of fusion genes may be an effective way of producing transgenic domestic animals which show controlled expression of the desired genes. Embryo manipulation and genetic engineering in livestock species is moving rapidly. The problems being addressed at present in numerous laboratories will result in enhanced livestock production in the not too distant future. Key words: Embryo transfer, embryo manipulation, transgenic livestock, genetic engineering, gene transfer, monozygotic twins

Regional localization of the LCA oncogene to human chromosome region 2q14→q21

1988 ◽  
Vol 48 (1) ◽  
pp. 63-64 ◽  
Author(s):  
T. Tokino ◽  
H. Satoh ◽  
M.C. Yoshida ◽  
T. Ochiya ◽  
K. Matsubara
Keyword(s):  
Human Chromosome ◽  
Chromosome Region ◽  
Regional Localization

Assignment of the gene coding for both the β-subunit of prolyl 4-hydroxylase and the enzyme disulfide isomerase to human chromosome region 17p11→qter

1988 ◽  
Vol 47 (1-2) ◽  
pp. 37-41 ◽  
Author(s):  
L. Pajunen ◽  
R. Myllylä ◽  
T. Helaakoski ◽  
T. Pihlajaniemi ◽  
K. Tasanen ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Chromosome Region ◽  
Beta Subunit ◽  
Disulfide Isomerase ◽  
Gene Coding

Localization of the uroporphyrinogen I synthase locus to human chromosome region 11q13→qter and interconversion of enzyme isomers

1981 ◽  
Vol 31 (2) ◽  
pp. 124-128 ◽  
Author(s):  
M.H. Meisler ◽  
L. Wanner ◽  
F.T. Kao ◽  
C. Jones
Keyword(s):  
Human Chromosome ◽  
Chromosome Region

Physical linkage of the gene cluster containing the LCAT gene to the DNA marker D16S124 at human chromosome region 16q22.1

1995 ◽  
Vol 68 (3-4) ◽  
pp. 194-196 ◽  
Author(s):  
E. Frengen ◽  
G. Brede ◽  
F. Larsen ◽  
G. Skretting ◽  
H. Prydz
Keyword(s):  
Human Chromosome ◽  
Gene Cluster ◽  
Dna Marker ◽  
Chromosome Region ◽  
Physical Linkage

scholarly journals 710 ASSIGNMENT OF THE FIRST HIGHLY POLYMORPHIC DNA MARKER LOCUS TO A HUMAN CHROMOSOME REGION

1981 ◽  
Vol 15 ◽  
pp. 560-560 ◽  
Author(s):  
Bérengère De Martinville ◽  
Arlene R Wyman ◽  
Ray White ◽  
Uta Francke
Keyword(s):  
Human Chromosome ◽  
Dna Marker ◽  
Chromosome Region ◽  
Marker Locus

Identification of human chromosome region 3p14.2–21.3-specific YAC clones using Alu-PCR products from a radiation hybrid

1994 ◽  
Vol 20 (2) ◽  
pp. 137-142
Author(s):  
Thomas S. Siden ◽  
Johan Kumlien ◽  
Timothy Drumheller ◽  
Scott E. Smith ◽  
Dan Röhme ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Radiation Hybrid ◽  
Chromosome Region ◽  
Pcr Products

Characterization of a Microdissection Library from Human Chromosome Region 3p14

Genomics ◽  
1994 ◽  
Vol 19 (2) ◽  
pp. 291-297 ◽  
Author(s):  
W. Bardenheuer ◽  
S. Szymanski ◽  
A. Lux ◽  
H.-J. Lüdecke ◽  
B. Horsthemke ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Chromosome Region
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