Nerve growth factor enhances the dendritic arborization of sympathetic ganglion cells undergoing atrophy in aged rats

1994 ◽  
Vol 23 (4) ◽  
pp. 234-241 ◽  
Author(s):  
T. J. Andrews ◽  
T. Cowen
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Sympathetic Ganglion ◽  
Ganglion Cells ◽  
Dendritic Arborization ◽  
Aged Rats ◽  
Nerve Growth

Nerve growth factor accelerates regeneration of cultured adult sympathetic ganglion cells

AGE ◽  
1985 ◽  
Vol 8 (1) ◽  
pp. 19-20 ◽  
Author(s):  
Y. Uchida ◽  
M. Tomonaga
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Sympathetic Ganglion ◽  
Ganglion Cells ◽  
Nerve Growth

Involvement of Nerve Growth Factor and Its Receptor in the Regulation of the Cholinergic Function in Aged Rats

1991 ◽  
Vol 57 (5) ◽  
pp. 1483-1487 ◽  
Author(s):  
Jordi Alberch ◽  
Esther Pérez-Navarro ◽  
Ernest Arenas ◽  
Jordi Marsa
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Aged Rats ◽  
Nerve Growth ◽  
Cholinergic Function

scholarly journals The Effects of Nerve Growth Factor on Spatial Recent Memory in Aged Rats Persist after Discontinuation of Treatment

1997 ◽  
Vol 17 (7) ◽  
pp. 2543-2550 ◽  
Author(s):  
Karyn M. Frick ◽  
Donald L. Price ◽  
Vassilis E. Koliatsos ◽  
Alicja L. Markowska
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Aged Rats ◽  
Nerve Growth ◽  
Recent Memory ◽  
Discontinuation Of Treatment

scholarly journals Effect of nerve growth factor on the release of inflammatory mediators by mature human basophils

Blood ◽  
1992 ◽  
Vol 79 (10) ◽  
pp. 2662-2669 ◽  
Author(s):  
SC Bischoff ◽  
CA Dahinden
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Inflammatory Mediators ◽  
Ganglion Cells ◽  
Neuronal Cell ◽  
Cell Types ◽  
Cell Fractionation ◽  
Hematopoietic Growth Factors ◽  
Nerve Growth ◽  
Human Basophils

Abstract Nerve growth factor (NGF) is a neurotrophic cytokine known to regulate the survival and function of peripheral and central neuronal cells. Recently, the spectrum of action could be extended to non-neuronal cell types such as rat mast cells and human B lymphocytes. The present study shows that NGF affects the function of mature human basophils isolated from the peripheral blood of healthy donors. Both murine NGF 7S and recombinant human NGF beta enhance histamine release and strongly modulate the formation of lipid mediators by basophils in response to various stimuli. This priming effect of NGF on basophils occurs rapidly within 10 to 15 minutes of preincubation, is dose-dependent, and requires similarly low concentrations (1 to 40 pmol/L) of human NGF beta as the induction of neurite outgrowth in ganglion cells. Cell fractionation studies indicate that NGF acts directly on human basophils without an involvement of other cell types, suggesting the presence of high-affinity NGF receptors on basophils. NGF by itself (up to 4 nmol/L of human NGF beta) does not induce the release of inflammatory mediators directly. The effect of human NGF on basophil mediator release is similar to that of the hematopoietic growth factors interleukin-3, interleukin-5, and granulocyte-macrophage colony- stimulating factor. The present study further demonstrates that NGF acts as a pleiotropic cytokine at the interface between the nervous and the immune system, and that NGF may be involved in inflammatory processes and hypersensitivity reactions.

Some characteristics of chick embryo sympathetic ganglion fragments in a simple culture system with and without nerve growth factor

1972 ◽  
Vol 138 (2) ◽  
pp. 127-133 ◽  
Author(s):  
D. R. Mottram ◽  
R. Presley ◽  
J. D. Lever ◽  
C. Ivens
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Chick Embryo ◽  
Culture System ◽  
Sympathetic Ganglion ◽  
Nerve Growth

Reduced transport of [125I]nerve growth factor by cholinergic neurons and down-regulated trka expression in the medial septum of aged rats

Neuroscience ◽  
1994 ◽  
Vol 62 (3) ◽  
pp. 625-629 ◽  
Author(s):  
J.D. Cooper ◽  
D. Lindholm ◽  
M.V. Sofroniew
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Cholinergic Neurons ◽  
Medial Septum ◽  
Aged Rats ◽  
Nerve Growth

The impact of two mild stressors on the nerve growth factor (NGF) immunoreactivity in the amygdala in aged rats compared to adult ones

2015 ◽  
Vol 49 (1) ◽  
pp. 6-13 ◽  
Author(s):  
Ewa Badowska‐Szalewska ◽  
Beata Ludkiewicz ◽  
Rafał Krawczyk ◽  
Janusz Moryś
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Aged Rats ◽  
Nerve Growth ◽  
The Impact
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