The covarion model for the evolution of proteins: Parameter estimates and comparison with holmquist, cantor, and Jukes' stochastic model

1979 ◽  
Vol 12 (3) ◽  
pp. 197-218 ◽  
Author(s):  
John M. Karon

2021 ◽  
Vol 15 (4) ◽  
pp. 607-614
Author(s):  
Feby Seru ◽  
Azizah Azizah ◽  
Agung Dwi Saputro

One of the crucial things in the insurance business is determining the amount of IBNR claim reserves. The amount of IBNR's claim reserves is uncertain so it is necessary to estimate as accurately as possible. The estimation results of IBNR's claim reserves will affect the solvency and sustainability of the company. To calculate the estimated IBNR claim reserves, several approaches are used both deterministically and stochastically. This study uses a stochastic model with the GLM approach for data that is assumed to have an ODP distribution. Besides, this study also uses 2 different methods to calculate parameter estimates in the model, namely by performing parameter transformations and using the Verbeek algorithm. This study will compare the results of the IBNR claim reserve estimation obtained using these two methods in estimating the parameters in the model. The estimation results obtained indicate that the value of the IBNR claim reserves is the same. The advantage of the Verbeek algorithm is that the resulting parameter values ​​have interpretations.



2015 ◽  
Vol 9 (2) ◽  
pp. 239-263 ◽  
Author(s):  
Annina Saluz

AbstractThe Cape Cod (CC) method was designed by Bühlmann and Straub in order to overcome some shortcomings of the chain ladder (CL) method. Owing to its simplicity and because of the advantages over the CL method, the CC method has become a well-established method in practice. In this paper we consider a distribution-free stochastic model for the CC method. Within this model we give the parameter estimates and we derive estimates for the conditional mean square error of prediction for the CC method. In addition, we derive an estimate for the uncertainty in the claims development result.



1999 ◽  
Vol 15 (2) ◽  
pp. 91-98 ◽  
Author(s):  
Lutz F. Hornke

Summary: Item parameters for several hundreds of items were estimated based on empirical data from several thousands of subjects. The logistic one-parameter (1PL) and two-parameter (2PL) model estimates were evaluated. However, model fit showed that only a subset of items complied sufficiently, so that the remaining ones were assembled in well-fitting item banks. In several simulation studies 5000 simulated responses were generated in accordance with a computerized adaptive test procedure along with person parameters. A general reliability of .80 or a standard error of measurement of .44 was used as a stopping rule to end CAT testing. We also recorded how often each item was used by all simulees. Person-parameter estimates based on CAT correlated higher than .90 with true values simulated. For all 1PL fitting item banks most simulees used more than 20 items but less than 30 items to reach the pre-set level of measurement error. However, testing based on item banks that complied to the 2PL revealed that, on average, only 10 items were sufficient to end testing at the same measurement error level. Both clearly demonstrate the precision and economy of computerized adaptive testing. Empirical evaluations from everyday uses will show whether these trends will hold up in practice. If so, CAT will become possible and reasonable with some 150 well-calibrated 2PL items.



Methodology ◽  
2005 ◽  
Vol 1 (2) ◽  
pp. 81-85 ◽  
Author(s):  
Stefan C. Schmukle ◽  
Jochen Hardt

Abstract. Incremental fit indices (IFIs) are regularly used when assessing the fit of structural equation models. IFIs are based on the comparison of the fit of a target model with that of a null model. For maximum-likelihood estimation, IFIs are usually computed by using the χ2 statistics of the maximum-likelihood fitting function (ML-χ2). However, LISREL recently changed the computation of IFIs. Since version 8.52, IFIs reported by LISREL are based on the χ2 statistics of the reweighted least squares fitting function (RLS-χ2). Although both functions lead to the same maximum-likelihood parameter estimates, the two χ2 statistics reach different values. Because these differences are especially large for null models, IFIs are affected in particular. Consequently, RLS-χ2 based IFIs in combination with conventional cut-off values explored for ML-χ2 based IFIs may lead to a wrong acceptance of models. We demonstrate this point by a confirmatory factor analysis in a sample of 2449 subjects.



Methodology ◽  
2015 ◽  
Vol 11 (3) ◽  
pp. 89-99 ◽  
Author(s):  
Leslie Rutkowski ◽  
Yan Zhou

Abstract. Given a consistent interest in comparing achievement across sub-populations in international assessments such as TIMSS, PIRLS, and PISA, it is critical that sub-population achievement is estimated reliably and with sufficient precision. As such, we systematically examine the limitations to current estimation methods used by these programs. Using a simulation study along with empirical results from the 2007 cycle of TIMSS, we show that a combination of missing and misclassified data in the conditioning model induces biases in sub-population achievement estimates, the magnitude and degree to which can be readily explained by data quality. Importantly, estimated biases in sub-population achievement are limited to the conditioning variable with poor-quality data while other sub-population achievement estimates are unaffected. Findings are generally in line with theory on missing and error-prone covariates. The current research adds to a small body of literature that has noted some of the limitations to sub-population estimation.



1964 ◽  
Vol 9 (7) ◽  
pp. 273-276
Author(s):  
ANATOL RAPOPORT
Keyword(s):  


1996 ◽  
Vol 6 (4) ◽  
pp. 445-453 ◽  
Author(s):  
Roberta Donato
Keyword(s):  


1987 ◽  
Vol 26 (03) ◽  
pp. 117-123
Author(s):  
P. Tautu ◽  
G. Wagner

SummaryA continuous parameter, stationary Gaussian process is introduced as a first approach to the probabilistic representation of the phenotype inheritance process. With some specific assumptions about the components of the covariance function, it may describe the temporal behaviour of the “cancer-proneness phenotype” (CPF) as a quantitative continuous trait. Upcrossing a fixed level (“threshold”) u and reaching level zero are the extremes of the Gaussian process considered; it is assumed that they might be interpreted as the transformation of CPF into a “neoplastic disease phenotype” or as the non-proneness to cancer, respectively.



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