Peripheral nerve autografts to the injured spinal cord of the rat: An experimental model for the study of spinal cord regeneration

1985 ◽  
Vol 78 (1-2) ◽  
pp. 57-64 ◽  
Author(s):  
E. Fernandez ◽  
R. Pallini ◽  
G. Maira ◽  
G. F. Rossi
Keyword(s):  
Spinal Cord ◽  
Peripheral Nerve ◽  
Experimental Model ◽  
Spinal Cord Regeneration ◽  
Injured Spinal Cord

scholarly journals Anisotropic scaffolds for peripheral nerve and spinal cord regeneration

2021 ◽  
Vol 6 (11) ◽  
pp. 4141-4160
Author(s):  
Wen Xue ◽  
Wen Shi ◽  
Yunfan Kong ◽  
Mitchell Kuss ◽  
Bin Duan
Keyword(s):  
Spinal Cord ◽  
Peripheral Nerve ◽  
Spinal Cord Regeneration

scholarly journals Combining Peripheral Nerve Grafts and Chondroitinase Promotes Functional Axonal Regeneration in the Chronically Injured Spinal Cord

2009 ◽  
Vol 29 (47) ◽  
pp. 14881-14890 ◽  
Author(s):  
V. J. Tom ◽  
H. R. Sandrow-Feinberg ◽  
K. Miller ◽  
L. Santi ◽  
T. Connors ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Peripheral Nerve ◽  
Axonal Regeneration ◽  
Injured Spinal Cord ◽  
Nerve Grafts ◽  
Peripheral Nerve Grafts

scholarly journals An experimental model for the transplantation of fetal central nervous system cells to the injured spinal cord in rats

2002 ◽  
Vol 57 (6) ◽  
pp. 257-264 ◽  
Author(s):  
Tarcísio Eloy Pessoa de Barros Filho ◽  
Reginaldo Perilo de Oliveira ◽  
Ana Maria Tsanaclis ◽  
Erika Meirelles Kalil Pessoa de Barros ◽  
Alexandre Fogaça Cristante ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Central Nervous System ◽  
Nervous System ◽  
Experimental Model ◽  
Fetal Tissue ◽  
Spinal Cord Tissue ◽  
Injured Spinal Cord ◽  
Functional Changes ◽  
Adult Rat ◽  
Cord Injury

INTRODUCTION: Traumatic spinal cord injury is one of the most disabling conditions occurring in man and thus stimulates a strong interest in its histopathological, biochemical, and functional changes, primarily as we search for preventive and therapeutic methods. PURPOSE: To develop an experimental model for transplantation of cells from the fetal rat central nervous system to the site of an injured spinal cord of an adult rat in which the transplanted cells survive and become integrated. This experimental model will facilitate investigations of factors that promote regeneration and functional recovery after spinal cord trauma. MATERIAL AND METHODS: Fifteen adult Wistar rats underwent laminectomy, and an spinal cord lesion was made with microdissection. Fetal spinal cord tissue was then transplanted to the site of the injury. The rats were monitored over a 48-hour period, and then their vertebral column was completely removed for histological analysis. RESULTS: In 60% of transplanted rats, the fetal tissue at the injured site remained viable in the site of the lesion.

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