Effects of chronic caffeine feeding on the activities of oxygen free radical defense enzymes in the growing rat heart and liver

1994 ◽  
Vol 50 (5) ◽  
pp. 465-468 ◽  
Author(s):  
M. J. Rossowska ◽  
T. Nakamoto
Keyword(s):  
Free Radical ◽  
Rat Heart ◽  
Oxygen Free Radical ◽  
Defense Enzymes ◽  
Growing Rat ◽  
Chronic Caffeine

Vascular effects of free radicals generated by electrical stimulation

1984 ◽  
Vol 247 (5) ◽  
pp. H709-H714 ◽  
Author(s):  
F. S. Lamb ◽  
R. C. Webb
Keyword(s):  
Electrical Stimulation ◽  
Free Radical ◽  
Experimental System ◽  
Electrical Field Stimulation ◽  
Oxygen Metabolism ◽  
Inhibitory Effect ◽  
Oxygen Free Radical ◽  
Vascular Effects ◽  
Electrical Field ◽  
Rat Tail

Electrical field stimulation (9 V, 1.0 ms, 4 Hz) of isolated segments of rat tail arteries and dog coronary arteries inhibits contractile responses to exogenous norepinephrine and elevated potassium concentration. This inhibitory effect of electrical stimulation is blocked by various agents that alter oxygen metabolism: superoxide dismutase, catalase, glutathione, ascorbate, and dimethyl sulfoxide. The observations suggest that the inhibitory effect is due to an action of oxygen free radical metabolites that are generated by the electrical stimulation of the oxygen-rich buffer. These free radical metabolites have two actions: 1) they oxidize drugs in the experimental system, and 2) they exert a direct inhibitory action on vascular smooth muscle.

Biochemical Mechanisms for Oxygen Free Radical Formation During Exercise

1990 ◽  
Vol 10 (4) ◽  
pp. 236-254 ◽  
Author(s):  
Bertil Sjödin ◽  
Ylva Hellsten Westing ◽  
Fred S. Apple
Keyword(s):  
Free Radical ◽  
Oxygen Free Radical ◽  
Radical Formation ◽  
Biochemical Mechanisms ◽  
Free Radical Formation
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