Stevens-Johnson syndrome with isolation ofMycoplasma pneumoniae from skin lesions

1986 ◽  
Vol 5 (2) ◽  
pp. 167-168 ◽  
Author(s):  
M. A. Meseguer ◽  
L. de Rafael ◽  
M. L. Vidal
Keyword(s):  
Skin Lesions ◽  
Stevens Johnson Syndrome ◽  
Johnson Syndrome

Paraneoplastic pemphigus associated with rapidly progressing endophthalmitis caused by Morganella Morganii: A case report

2021 ◽  
pp. 112067212110334
Author(s):  
Abdullah I Almater ◽  
Mohammed M Abusayf ◽  
Saeed Alshahrani ◽  
Abdullah M Alfawaz ◽  
Hind M Alkatan ◽  
...  
Keyword(s):  
Positive Culture ◽  
Skin Lesions ◽  
Stevens Johnson Syndrome ◽  
Corneal Perforation ◽  
Morganella Morganii ◽  
Paraneoplastic Pemphigus ◽  
First Case ◽  
Johnson Syndrome ◽  
Acute Necrotizing ◽  
The Right

Introduction: The ocular presentation of paraneoplastic pemphigus (PNP) has rarely been reported in the literature. In this report, we describe a 61-year-old male presenting with eruptive skin lesions associated with underlying non-Hodgkin’s lymphoma who had rapid progressive corneal perforation with secondary endophthalmitis in the setting of PNP. Case description: A 61-year-old male presented to the emergency department complaining of skin eruption mimicking Stevens–Johnson syndrome, which was later found to be related to PNP. Initially, the patient complained of progressive ocular surface dryness in both eyes. Meanwhile, he developed mild pain in the right eye associated with blurry vision in both eyes and was managed with lubricants and topical antibiotics. A few days later, he was found to have corneal perforation with features suggestive of left endophthalmitis with possible early panophthalmitis. Intravenous antibiotic was administered, and primary evisceration of the left globe was performed. Histopathology revealed acute necrotizing keratitis and endophthalmitis. Vitreous analysis showed numerous gram-negative bacilli and a positive culture of Morganella morganii. The patient continued to be managed with frequent lubrications and punctual plugs in the fellow eye during the follow-up period. Conclusion: We describe the first case of endophthalmitis developing secondary to PNP-induced corneal melting and perforation. Anticipating unusual infectious sequelae in the setting of PNP might be warranted to actively detect and successfully manage dry eye disease before devastating complications develop.

scholarly journals Stevens-Johnson Syndrome without Skin Lesions: A Rare and Clinically Challenging Disease in the Urgent Setting

2015 ◽  
Vol 1 (2) ◽  
pp. 22-30
Author(s):  
Ursula M. Anders ◽  
◽  
Elise J. Taylor ◽  
Victoria Kravchuk ◽  
Joseph R. Martel ◽  
...  
Keyword(s):  
Skin Lesions ◽  
Stevens Johnson Syndrome ◽  
Johnson Syndrome

Cephalexin-Induced Stevens-Johnson Syndrome

1992 ◽  
Vol 26 (10) ◽  
pp. 1230-1233 ◽  
Author(s):  
Kim M. Murray ◽  
Michael S. Camp
Keyword(s):  
Gastrointestinal Tract ◽  
Lupus Erythematosus ◽  
Skin Surface ◽  
Skin Lesions ◽  
Infectious Complications ◽  
The Body ◽  
Stevens Johnson Syndrome ◽  
Medline Search ◽  
Johnson Syndrome ◽  
Macular Rash

OBJECTIVE: To report a case of cephalexin-induced Stevens-Johnson syndrome (SJS), a devastating adverse drug reaction that involves the entire skin surface and mucosal areas of the body. DATA SOURCES: MEDLINE search (key terms cephalosporins, Stevens-Johnson syndrome, erythema multiforme, and systemic lupus erythematosus) and references identified from bibliographies of pertinent articles. DATA SYNTHESIS: Clinical presentation and manifestations of SJS include the skin, eyes, gastrointestinal tract, and pulmonary system. Infectious complications are the leading cause of mortality. Early intervention is important to prevent progression of SJS. The case described is consistent with the features of this syndrome. The patient presented with fever, arthralgias, and malaise. Skin lesions included a diffuse violet macular rash with erythema and multiple bullous lesions on her neck and abdomen. The skin biopsy was consistent with SJS. Multiple mucocutaneous ulcers were found in her mouth, but no evidence of lower gastrointestinal tract involvement was documented. She remained relatively free of pulmonary complaints except for the presenting bronchitis. CONCLUSIONS: Cephalexin should be added to the list of agents to consider as iatrogenic causes of SJS.

The Spectrum of Erythema Multiforme

1996 ◽  
Vol 17 (2) ◽  
pp. 63-64
Author(s):  
Daniel Rauch
Keyword(s):  
Hypersensitivity Reaction ◽  
Toxic Epidermal Necrolysis ◽  
Erythema Multiforme ◽  
Skin Lesions ◽  
Stevens Johnson Syndrome ◽  
Major Type ◽  
Age Group ◽  
Pediatric Age ◽  
Pediatric Age Group ◽  
Johnson Syndrome

Erythema multiforme (EM) is an acute hypersensitivity reaction characterized by distinctive skin lesions and mucous membrane involvement that has a spectrum of severity. It occurs in two forms: the more common "minor" type and the more severe "major" type, also called Stevens-Johnson syndrome (SJS). Sometimes EM includes toxic epidermal necrolysis (TEN) or Lyell disease. EM minor first was described completely by von Hebra in 1866; Stevens and Johnson described the major variant in 1922. EM occurs more often in males, and 20% to 50% of cases occur in the pediatric age group, although rarely in those younger than age 3 years.

Dermatology

2019 ◽  
pp. 213-230
Keyword(s):  
Skin Cancer ◽  
Acne Vulgaris ◽  
Systemic Disease ◽  
Skin Lesions ◽  
Punch Biopsy ◽  
Stevens Johnson Syndrome ◽  
Clinical Approach ◽  
Dermatology Clinic ◽  
Skin Cancers ◽  
Johnson Syndrome

Dermatology is the study of the skin, hair, nails, and oral and genital mucus membranes and the diseases affecting them. It is predominantly an outpatient specialty. This chapter explains the common terminology used to describe skin lesions and dermatoses. The commonest conditions encountered in the dermatology clinic are described: eczema, psoriasis, pyoderma gangrenosum, skin cancers (basal cell skin cancer, squamous cell skin cancer, malignant melanoma), acne vulgaris and bullous disorders, in addition to dermatological manifestations of systemic disease such as vasculitis. Emergency presentations such as Stevens–Johnson syndrome/toxic epidermal necrolysis, anaphylaxis, and necrotizing fasciitis are outlined. A practical guide to common dermatological procedures such as punch biopsy, and a clinical approach to the dermatological patient are included.

scholarly journals Peculiarities of the clinical course of allergic dermatoses in children (literature review)

2020 ◽  
pp. 58-63
Author(s):  
O.M. Mochulska ◽  
◽  
K.T. Hlushko ◽  
Keyword(s):  
Skin Diseases ◽  
Clinical Course ◽  
Clinical Manifestations ◽  
Allergic Diseases ◽  
Skin Lesions ◽  
Stevens Johnson Syndrome ◽  
Clinical Criteria ◽  
Johnson Syndrome ◽  
Allergic Skin ◽  
Allergic Contact

The prevalence of allergic diseases is constantly growing around the world. According to WHO forecasts, most of the world's population will suffer from various allergies by 2050, at the same time any substance can be an allergen, and the XXI century will be the era of allergies. In the structure of allergic diseases in children the leading place is occupied by allergic skin lesions — allergic dermatoses, which are characterized by pronounced clinical polymorphism, acute or chronic stage with the development of concomitant pathological changes in many systems of the growing child's body. Allergic dermatoses are a large group of skin diseases, including: simple and allergic contact dermatitis, atopic dermatitis, various forms of eczema, acute and chronic allergic urticaria, Quincke's edema, multiforme exudative erythema (Stevens-Johnson syndrome), acute epidermal necrolysis (Lyell's syndrome), toxicodermias, as well as less common dermatoses, in the pathogenesis of which are leading allergic reactions. Purpose — to describe clinical criteria for the differential diagnosis of allergodermatoses in children in order to increase its effectiveness. Conclusions. Allergodermatoses in children are characterized by polymorphism of clinical manifestations, which depends on the specific nosology. There is a tendency to increase the frequency of allergic skin diseases in children, especially severe forms with recurrent course, resistant to traditional pharmacotherapy. Comprehensive detailed study of clinical manifestations of allergic dermatoses in children will contribute to the development of differential diagnostic criteria for allergic dermatoses in children, to verify accurate diagnosis and to prescribe the pathogenesis-based treatment for various allergic skin diseases in time. No conflict of interest was declared by the authors. Key words: children, allergy, allergic dermatoses, clinical criteria.

Fuchs Syndrome Associated with Mycoplasma pneumoniae (Stevens-Johnson Syndrome without Skin Lesions)

2010 ◽  
Vol 28 (4) ◽  
pp. 474-476 ◽  
Author(s):  
PATRICK MICHAEL MEYER SAUTEUR ◽  
URSULA GANSSER-KÄLIN ◽  
STEPHAN LAUTENSCHLAGER ◽  
PHILIPPE GOETSCHEL
Keyword(s):  
Mycoplasma Pneumoniae ◽  
Skin Lesions ◽  
Stevens Johnson Syndrome ◽  
Johnson Syndrome
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