Dermatology

Dermatology is the study of the skin, hair, nails, and oral and genital mucus membranes and the diseases affecting them. It is predominantly an outpatient specialty. This chapter explains the common terminology used to describe skin lesions and dermatoses. The commonest conditions encountered in the dermatology clinic are described: eczema, psoriasis, pyoderma gangrenosum, skin cancers (basal cell skin cancer, squamous cell skin cancer, malignant melanoma), acne vulgaris and bullous disorders, in addition to dermatological manifestations of systemic disease such as vasculitis. Emergency presentations such as Stevens–Johnson syndrome/toxic epidermal necrolysis, anaphylaxis, and necrotizing fasciitis are outlined. A practical guide to common dermatological procedures such as punch biopsy, and a clinical approach to the dermatological patient are included.

2021 ◽  
pp. 112067212110334
Author(s):  
Abdullah I Almater ◽  
Mohammed M Abusayf ◽  
Saeed Alshahrani ◽  
Abdullah M Alfawaz ◽  
Hind M Alkatan ◽  
...  

Introduction: The ocular presentation of paraneoplastic pemphigus (PNP) has rarely been reported in the literature. In this report, we describe a 61-year-old male presenting with eruptive skin lesions associated with underlying non-Hodgkin’s lymphoma who had rapid progressive corneal perforation with secondary endophthalmitis in the setting of PNP. Case description: A 61-year-old male presented to the emergency department complaining of skin eruption mimicking Stevens–Johnson syndrome, which was later found to be related to PNP. Initially, the patient complained of progressive ocular surface dryness in both eyes. Meanwhile, he developed mild pain in the right eye associated with blurry vision in both eyes and was managed with lubricants and topical antibiotics. A few days later, he was found to have corneal perforation with features suggestive of left endophthalmitis with possible early panophthalmitis. Intravenous antibiotic was administered, and primary evisceration of the left globe was performed. Histopathology revealed acute necrotizing keratitis and endophthalmitis. Vitreous analysis showed numerous gram-negative bacilli and a positive culture of Morganella morganii. The patient continued to be managed with frequent lubrications and punctual plugs in the fellow eye during the follow-up period. Conclusion: We describe the first case of endophthalmitis developing secondary to PNP-induced corneal melting and perforation. Anticipating unusual infectious sequelae in the setting of PNP might be warranted to actively detect and successfully manage dry eye disease before devastating complications develop.


2015 ◽  
Vol 1 (2) ◽  
pp. 22-30
Author(s):  
Ursula M. Anders ◽  
◽  
Elise J. Taylor ◽  
Victoria Kravchuk ◽  
Joseph R. Martel ◽  
...  

1992 ◽  
Vol 26 (10) ◽  
pp. 1230-1233 ◽  
Author(s):  
Kim M. Murray ◽  
Michael S. Camp

OBJECTIVE: To report a case of cephalexin-induced Stevens-Johnson syndrome (SJS), a devastating adverse drug reaction that involves the entire skin surface and mucosal areas of the body. DATA SOURCES: MEDLINE search (key terms cephalosporins, Stevens-Johnson syndrome, erythema multiforme, and systemic lupus erythematosus) and references identified from bibliographies of pertinent articles. DATA SYNTHESIS: Clinical presentation and manifestations of SJS include the skin, eyes, gastrointestinal tract, and pulmonary system. Infectious complications are the leading cause of mortality. Early intervention is important to prevent progression of SJS. The case described is consistent with the features of this syndrome. The patient presented with fever, arthralgias, and malaise. Skin lesions included a diffuse violet macular rash with erythema and multiple bullous lesions on her neck and abdomen. The skin biopsy was consistent with SJS. Multiple mucocutaneous ulcers were found in her mouth, but no evidence of lower gastrointestinal tract involvement was documented. She remained relatively free of pulmonary complaints except for the presenting bronchitis. CONCLUSIONS: Cephalexin should be added to the list of agents to consider as iatrogenic causes of SJS.


1996 ◽  
Vol 17 (2) ◽  
pp. 63-64
Author(s):  
Daniel Rauch

Erythema multiforme (EM) is an acute hypersensitivity reaction characterized by distinctive skin lesions and mucous membrane involvement that has a spectrum of severity. It occurs in two forms: the more common "minor" type and the more severe "major" type, also called Stevens-Johnson syndrome (SJS). Sometimes EM includes toxic epidermal necrolysis (TEN) or Lyell disease. EM minor first was described completely by von Hebra in 1866; Stevens and Johnson described the major variant in 1922. EM occurs more often in males, and 20% to 50% of cases occur in the pediatric age group, although rarely in those younger than age 3 years.


Author(s):  
Sanju Arianayagam

This chapter in the Oxford Handbook of Clinical Specialties explores the specialty of dermatology. It works up from the basics of dermatology through describing a lesion and patterns of skin disease to itch and signs of systemic disease. Cancer is reviewed, including common skin cancers and premalignant tumours and malignant melanoma. Psoriasis is explored, along with eczema, skin infections, acne vulgaris, rosacea, drug eruptions, photosensitivity, urticaria, ulcers, HIV, infestations, and psychodermatoses.


Author(s):  
Andrew Baldwin ◽  
Nina Hjelde ◽  
Charlotte Goumalatsou ◽  
Gil Myers

This chapter explores dermatology. It includes history and examination, creams and ointments, describing a lesion, patterns of skin disease, itch, skin signs in systemic disease, common skin cancers, malignant melanoma, moles, psoriasis, eczema (dermatitis), skin infections (fungi, bacteria, viruses), acne vulgaris, rosacea, drug eruptions, specific skin disorders (pemphigus and pemphigoid, strawberry naevus, pyogenic granuloma, lichen planus, pityriasis rosea, alopecia, photosensitivity, urticaria), venous ulcers, pressure sores, skin disorders and HIV, infestations, and psychodermatoses.


2012 ◽  
Vol 3 (3) ◽  
pp. 158-165 ◽  
Author(s):  
Carrie Newlands

Skin cancer is increasing in incidence and the face is the commonest site for skin cancers to occur. Patients who are at risk from skin cancers include those who have fair skin and who have had long-term exposure to sunshine.1 While facial skin cancers are more common in the older population, greater numbers of younger people are developing these cancers.2-4 Facial skin lesions are common. This article aims to help members of the dental team recognise the features of those lesions which may indicate malignancy or pre-malignancy.


1986 ◽  
Vol 5 (2) ◽  
pp. 167-168 ◽  
Author(s):  
M. A. Meseguer ◽  
L. de Rafael ◽  
M. L. Vidal

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