Fecal diversion in the management of Crohnʼs disease of the colon

1993 ◽  
Vol 36 (8) ◽  
pp. 757-762 ◽  
Author(s):  
Mark C. Winslet ◽  
Hilary Andrews ◽  
Robert N. Allan ◽  
Michael R. B. Keighley
Keyword(s):  
Author(s):  
K Talboom ◽  
I Vogel ◽  
R D Blok ◽  
S X Roodbeen ◽  
C Y Ponsioen ◽  
...  

Abstract In this single center case series with nine percent primary diversion, 86 of 94 patients alive and with complete follow-up at one year had a functioning anastomosis. Seventy-five of the initial 99 patients never had a stoma. Meaning: Highly selective fecal diversion in combination with proactive leakage management, low anastomoses can be preserved safely, and the majority of patients will be spared all disadvantages of a diverting stoma. In this single-centre case series, with a primary diversion rate of 9 per cent, 86 of 94 patients who were alive and had complete follow-up at 1 year had a functioning anastomosis. Seventy-five of the initial 99 patients never had a stoma. The results indicate that, with highly selective faecal diversion in combination with proactive leakage management, low anastomoses can be preserved safely, and the majority of patients will be spared the disadvantages of a diverting stoma.


1981 ◽  
Vol 24 (2) ◽  
pp. 114-119 ◽  
Author(s):  
P. Wara ◽  
K. Sørensen ◽  
V. Berg
Keyword(s):  

2021 ◽  
Vol 9 (25) ◽  
pp. 7306-7310
Author(s):  
Pankaj Garg ◽  
Vipul D Yagnik ◽  
Sushil Dawka

Author(s):  
Alban Zarzavadjian Le Bian ◽  
Nicolas Tabchouri ◽  
Christine Denet ◽  
Théophile Guilbaud ◽  
Anaïs Laforest ◽  
...  

2020 ◽  
Vol 86 (10) ◽  
pp. 1277-1280
Author(s):  
Hassan Buhulaigah ◽  
Adam Truong ◽  
Karen Zaghiyan ◽  
Phillip Fleshner

Up to 80% of Crohn’s disease (CD) patients require surgery. Fecal diversion is used selectively in CD proctocolitis refractory to medical treatment or advanced perianal disease. This study examines associations between clinical features in predicting clinical response (CR) to fecal diversion in CD. Charts of CD patients undergoing fecal diversion for medically refractory disease or perianal disease were reviewed. Clinical response was assessed focusing on improvements in urgency, abdominal and perineal pain, decreased anal fistula drainage, and weight gain. Univariate binary logistic regression and multivariate forward-stepwise modeling analysis were used to determine associations with CR. The study cohort comprised 79 patients. After a median follow-up of 36 (3-192) months, 40 (51%) patients achieved a CR. Binary logistic regression analysis revealed both age at diagnosis (hazard ratio [HR] 1.05; confidence interval [CI] 1.01-1.09; P = .007) and disease duration (HR .91; CI .86-.96; P = .001) to be significantly associated with CR. Later age of onset (HR 1.05; CI 1.01-1.10; P = .002) and shorter disease duration (HR .91; CI .86-.97; P = .02) remained significant on multivariate analysis. This largest reported series of fecal diversion for refractory CD in the biologic drug era revealed that young age at diagnosis and long disease duration are associated with a lower CR.


2020 ◽  
Vol 158 (6) ◽  
pp. S-728
Author(s):  
Jacqueline Reid ◽  
Colin B. Rumbolt ◽  
Robert A. Mitchell ◽  
Cherry Galorport ◽  
Jacqueline Brown ◽  
...  

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