Na, K ATPase activity during early postnatal development of the rat submandibular gland

1987 ◽  
Vol 43 (5) ◽  
pp. 570-572 ◽  
Author(s):  
J. Camden ◽  
J. R. Martinez
Keyword(s):  
Atpase Activity ◽  
Postnatal Development ◽  
Submandibular Gland ◽  
Early Postnatal Development ◽  
Rat Submandibular Gland

Activation of ouabain-sensitive p-nitrophenylphosphatase by carbachol and cGMP in rat submandibular gland

1980 ◽  
Vol 58 (10) ◽  
pp. 1223-1229 ◽  
Author(s):  
Maggie M. Shi ◽  
D. J. Stewart ◽  
A. K. Sen
Keyword(s):  
Enzyme Activity ◽  
Atpase Activity ◽  
Submandibular Gland ◽  
Second Messenger ◽  
Sodium Ion ◽  
Cholinergic Stimulation ◽  
Minimal Requirement ◽  
Primary Fluid ◽  
Fluid Formation ◽  
Rat Submandibular Gland

Na+,K+-ATPase activity was monitored by measuring ouabain-sensitive K+-dependent p-nitrophenylphosphatase (p-NPPase) activity in rat submandibular gland slices. Carbachol (carbamylcholine chloride) stimulated the p-NPPase activity in the presence of calcium but not in its absence. Carbachol activation of the enzyme was totally ouabain sensitive and could be blocked by atropine. A minimal requirement of sodium ion extracellularly was required for this carbachol stimulation. cGMP and its dibutyryl analogue was also effective in stimulating the enzyme activity, whereas, cAMP was ineffective. Calcium, however, was not required for cGMP activation of the p-NPPase activity. The result indicates that calcium is the second messenger and cGMP is the tertiary connection between cholinergic stimulation and Na+,K+-ATPase activation in these glands. Activation of Na+,K+-ATPase is postulated to be responsible for primary fluid formation.

scholarly journals Developmental distribution of microperoxisomes in the rat submandibular gland.

1978 ◽  
Vol 26 (11) ◽  
pp. 989-999 ◽  
Author(s):  
B A Mooradian ◽  
L S Cutler
Keyword(s):  
Postnatal Development ◽  
Submandibular Gland ◽  
Acinar Cell ◽  
Secretory Cell ◽  
Fold Increase ◽  
Duct Cells ◽  
Size Number ◽  
Tubule Cells ◽  
Prenatal And Postnatal Development ◽  
Rat Submandibular Gland

The present study investigated the size, number, and distribution of microperoxisomes (MP) during the prenatal and postnatal development of the rat submandibular gland (SMG). A three-fold increase in MP number per cell was observed in the cells of the rudiment from the 15th to the 16th day of gestation. The early secretory and striated duct cells contained about 9.0 MP. The number of MP per secretory cell decreased such that 3.5 MP were found in each mature acinar cell. In the striated duct cells, MP number progressively increased to 40.0. As the convoluted granular tubule cells (CGT) developed from striated duct cells there was an increase in MP number from 16.0 to 26.0/cell. At maturity, the convoluted granular tubule cells contained only 14.0 MP. Throughout development of the SMG, intercalated duct cells showed only rare MP. The data suggests that the number, size, and distribution of MP changes as a function of the particular path of differentiation followed by the various cells in the rat SMG.

Effects of chemical sympathectomy on postnatal development of the rat submandibular gland

1988 ◽  
Vol 33 (2) ◽  
pp. 127-134
Author(s):  
L.S. Cutler ◽  
Constance P. Christian ◽  
B. Bottaro
Keyword(s):  
Postnatal Development ◽  
Submandibular Gland ◽  
Chemical Sympathectomy ◽  
Rat Submandibular Gland

Developmental Distribution of Microperoxisomes in the Rat Submandibular Gland

1977 ◽  
Vol 35 ◽  
pp. 426-427
Author(s):  
B.A. Mooradian ◽  
L.S. Cutler
Keyword(s):  
Postnatal Development ◽  
Submandibular Gland ◽  
Cell Types ◽  
Functional Differentiation ◽  
Secretory Cells ◽  
Ductal Cells ◽  
Size Number ◽  
Rat Submandibular Gland

In the mature rat submandibular gland (SMG) microperoxisomes have been identified in both acinar secretory cells and ductal cells. The present study was undertaken to investigate the size, number and distribution of microperoxisomes during the pre and postnatal development of the SMG in order to determine if there were changes in cellular microperoxisomes during the functional differentiation of the various cell types.

scholarly journals Transient occurrence of 27 kDa heat-shock protein in the terminal tubule cells during postnatal development of the rat submandibular gland

2001 ◽  
Vol 264 (4) ◽  
pp. 358-366 ◽  
Author(s):  
Osamu Amano ◽  
Yoshinori Kudo ◽  
Mayumi Shimada ◽  
Tomohiko Wakayama ◽  
Miyuki Yamamoto ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Postnatal Development ◽  
Submandibular Gland ◽  
Tubule Cells ◽  
Rat Submandibular Gland
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