The postnatal development of myoepithelial cells in the rat submandibular gland

1972 ◽  
Vol 10 (1) ◽  
pp. 253-262 ◽  
Author(s):  
S. E. Line ◽  
F. L. Archer
Keyword(s):  
Postnatal Development ◽  
Submandibular Gland ◽  
Myoepithelial Cells ◽  
Rat Submandibular Gland

scholarly journals Developmental distribution of microperoxisomes in the rat submandibular gland.

1978 ◽  
Vol 26 (11) ◽  
pp. 989-999 ◽  
Author(s):  
B A Mooradian ◽  
L S Cutler
Keyword(s):  
Postnatal Development ◽  
Submandibular Gland ◽  
Acinar Cell ◽  
Secretory Cell ◽  
Fold Increase ◽  
Duct Cells ◽  
Size Number ◽  
Tubule Cells ◽  
Prenatal And Postnatal Development ◽  
Rat Submandibular Gland

The present study investigated the size, number, and distribution of microperoxisomes (MP) during the prenatal and postnatal development of the rat submandibular gland (SMG). A three-fold increase in MP number per cell was observed in the cells of the rudiment from the 15th to the 16th day of gestation. The early secretory and striated duct cells contained about 9.0 MP. The number of MP per secretory cell decreased such that 3.5 MP were found in each mature acinar cell. In the striated duct cells, MP number progressively increased to 40.0. As the convoluted granular tubule cells (CGT) developed from striated duct cells there was an increase in MP number from 16.0 to 26.0/cell. At maturity, the convoluted granular tubule cells contained only 14.0 MP. Throughout development of the SMG, intercalated duct cells showed only rare MP. The data suggests that the number, size, and distribution of MP changes as a function of the particular path of differentiation followed by the various cells in the rat SMG.

scholarly journals Morphological Changes of Myoepithelial Cells in the Rat Submandibular Gland Following the Application of Surgical Stimuli

2016 ◽  
Vol 49 (6) ◽  
pp. 159-169 ◽  
Author(s):  
Yoshihiro Kawabe ◽  
Kenich Mizobe ◽  
Yasuhiko Bando ◽  
Koji Sakiyama ◽  
Fuyoko Taira ◽  
...  
Keyword(s):  
Submandibular Gland ◽  
Morphological Changes ◽  
Myoepithelial Cells ◽  
Rat Submandibular Gland

Effects of chemical sympathectomy on postnatal development of the rat submandibular gland

1988 ◽  
Vol 33 (2) ◽  
pp. 127-134
Author(s):  
L.S. Cutler ◽  
Constance P. Christian ◽  
B. Bottaro
Keyword(s):  
Postnatal Development ◽  
Submandibular Gland ◽  
Chemical Sympathectomy ◽  
Rat Submandibular Gland

scholarly journals Fine structural localization of acetylcholinesterase activity in rat submandibular gland.

1985 ◽  
Vol 33 (5) ◽  
pp. 439-445 ◽  
Author(s):  
A Topilko ◽  
B Caillou
Keyword(s):  
Submandibular Gland ◽  
Ache Activity ◽  
Membrane System ◽  
Ultrastructural Localization ◽  
Acetylcholinesterase Activity ◽  
Myoepithelial Cells ◽  
Biologically Active ◽  
Intracytoplasmic Membrane ◽  
Structural Localization ◽  
Rat Submandibular Gland

Using the indirect thiocholine method, the ultrastructural localization of acetylcholinesterase (AChE) activity in the normal rat submandibular gland was studied. Cytochemical demonstration of AChE is based on coupling the hydrolysis of acetylthiocholine iodide to the precipitation of heavy metal salts. AChE-associated reaction product was selectively revealed in the perinuclear space and in the endoplasmic reticulum of the intercalated duct cells, in some cells of granular convoluted tubules, and in the striated duct epithelium, as well as in the myoepithelial cells. Although AChE activity generally occurred inside the cells, electron-dense precipitates were shown in intercellular space and in the stroma of the gland. Fine localization of AChE activity was also found in nerve bundles, predominantly between axons and between axons and Schwann cell. Our observations indicate that AChE is synthesized in the epithelium of the ducts and in the myoepithelial cells of the salivary gland. It is not known yet whether this enzyme is released from the intracytoplasmic membrane system into the extracellular space and then transported to the regions of the gland innervation. Conceivably AChE synthesized in the submandibular gland cells could also be considered an inhibitory modulator of the regulatory functions of biologically active polypeptides.

Developmental Distribution of Microperoxisomes in the Rat Submandibular Gland

1977 ◽  
Vol 35 ◽  
pp. 426-427
Author(s):  
B.A. Mooradian ◽  
L.S. Cutler
Keyword(s):  
Postnatal Development ◽  
Submandibular Gland ◽  
Cell Types ◽  
Functional Differentiation ◽  
Secretory Cells ◽  
Ductal Cells ◽  
Size Number ◽  
Rat Submandibular Gland

In the mature rat submandibular gland (SMG) microperoxisomes have been identified in both acinar secretory cells and ductal cells. The present study was undertaken to investigate the size, number and distribution of microperoxisomes during the pre and postnatal development of the SMG in order to determine if there were changes in cellular microperoxisomes during the functional differentiation of the various cell types.

scholarly journals FINE STRUCTURAL LOCALIZATION OF CHOLINESTERASE ACTIVITY IN THE RAT SUBMANDIBULAR GLAND

1970 ◽  
Vol 18 (10) ◽  
pp. 730-739 ◽  
Author(s):  
BRUCE I. BOGART
Keyword(s):  
Smooth Muscle ◽  
Schwann Cell ◽  
Smooth Muscle Cells ◽  
Submandibular Gland ◽  
Muscle Cells ◽  
Acetylcholinesterase Activity ◽  
Myoepithelial Cells ◽  
Rat Submandibular Gland ◽  
Cell Interface ◽  
Axonal Swellings

The innervation of the rat submandibular gland was investigated by means of electron microscopy and cytochemical techniques. Axonal swellings partially depleted of their Schwann cell investment were observed in relationship to myoepithelial cells, acinar cells, ducts, capillaries and smooth muscle cells of arterioles. No direct contacts were found to exist between these elements and the nerve fibers. Axonal swellings containing mitochondria and vesicles fell into two distinct types: those characterized by small agranular vesicles and larger vesicles with pale cores and those characterized by small agranular vesicles and small vesicles with dense cores. Reaction product due to acetylcholinesterase activity was observed to be associated with the axolemma and the Schwann cell membrane at the axon-Schwann cell interface of many unmyelinated nerves found in relationship to both the vascular and parenchymal elements of the gland. Activity was found in association with the surface pits and vesicles of myoepithelial cells and arteriolar smooth muscle cells and with the rough endoplasmic reticulum and the nuclear envelope of the myoepithelial cells. Axonal swellings devoid of activity were observed particularly in relationship to arterioles. Reaction product was found only at the axon-Schwann cell interface when sections were incubated in medium for the demonstration of butyrylcholinesterase activity, while no reaction product was found upon addition of eserine sulfate to any of the media. The possibility that the reaction product due to acetylcholinesterase activity observed in association with the axolemma and the surface vesicles and pits of the myoepithelial cells and the arteriolar smooth muscle cells may define the autonomic cholinergic junction in the rat submandibular gland was explored.

Sign in / Sign up

Export Citation Format

Share Document