Influence of stimulation of the medial hypothalamus on the interaction of neurons of the rabbit neocortex

1996 ◽  
Vol 26 (4) ◽  
pp. 313-320 ◽  
Author(s):  
I. V. Pavlova ◽  
I. V. Volkov ◽  
V. N. Mats

1984 ◽  
Vol 247 (1) ◽  
pp. H139-H145 ◽  
Author(s):  
M. M. Knuepfer ◽  
A. K. Johnson ◽  
M. J. Brody

The anteroventral third ventricle (AV3V) region is necessary for the development of a variety of models of experimental hypertension. Neuroanatomic studies have identified descending projections from this region to the mesencephalic central gray and tegmentum. This study was done to identify functionally the projections involved in cardiovascular regulation from the AV3V region to the mesencephalon. Regional hemodynamic responses to electrical stimulation of the AV3V region were compared with responses to stimulation of the rostral central gray, and these responses were compared before and after ablation of mesencephalic tissue. Stimulation of the AV3V region elicited hindquarter, vasodilation and renal and mesenteric vasoconstriction associated with a depressor response and bradycardia. These responses were partially dependent on adrenal catecholamines since adrenalectomy reduced hindquarter, mesenteric, and depressor responses. Regional hemodynamic responses to central gray stimulation were qualitatively similar and also demonstrated a partial dependence on adrenal catecholamines. After electrolyte ablation of central gray tissue, significant reductions in hindquarter, mesenteric, and depressor responses to AV3V stimulation were observed. These observations suggest that a cardiovascular control system important for the development of several models of hypertension may be dependent on neuronal projections from the rostral medial hypothalamus through the mesencephalic central gray.



1989 ◽  
Vol 499 (1) ◽  
pp. 131-140 ◽  
Author(s):  
J. Duysens ◽  
R. Dom ◽  
J. Gybels




1970 ◽  
Vol 19 (2) ◽  
pp. 70-75
Author(s):  
Md Shahidul Haque ◽  
Takashi Shimazu

A very low dose of leptin (50 ng) was microinjected into the ventro-medial hypothalamus (VMH) of each rat daily once for three days. Food intake and body weight were measured after leptin injections. Microinjection of leptin into the VMH reduced food intake by 33.3 % significantly (P<0.01) during three days of leptin injection compared to the control. Body weight was measured after 24 h, 48 h and 72 h of leptin injection. After 24 h (P<0.01) and 48 h (P<0.05) of leptin injection, body weight was reduced significantly compared to that of rat before injection. Similarly, after 72 h of leptin injection, a significant reduced body weight was observed (P<0.1). A significant (P<0.001) reduced changes of body weight were found after 24 h, 48 h and 72 h after injection into the VMH when compared to the respective controls injected with saline. The results suggest that leptin has dramatic effect on reducing body weight by inhibition of food intake.   doi: 10.3329/taj.v19i2.3154 TAJ 2006; 19(2): 70-75





1970 ◽  
Vol 46 (3) ◽  
pp. 305-311 ◽  
Author(s):  
F. PRZEKOP ◽  
E. DOMAŃSKI

SUMMARY Electrical stimulation of the anterior hypothalamus (regions of the supraoptic and anterior hypothalamic nuclei) or of the ventro-medial hypothalamus (infundibular or ventro-medial nuclei) during the last month of anoestrus in ewes induced ovulation within 72 hr., while similar stimulation of the same centres during the breeding season on the 12th day of the oestrous cycle did not advance ovulation. The role of the hypothalamic centres in the control of gonadotrophin secretion and ovulation is discussed in the light of these results.



1995 ◽  
Vol 674 (2) ◽  
pp. 265-274 ◽  
Author(s):  
Maria Cristina Leite Silveira ◽  
Guy Sandner ◽  
Georges Di Scala ◽  
Frederico Guilherme Graeff


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