Cell surface antigen Thy-1

1989 ◽  
Vol 30 (4) ◽  
pp. 314-314
Author(s):  
H. -G. Rammensee
Keyword(s):  
Cell Surface ◽  
Surface Antigen ◽  
Cell Surface Antigen

Detection and Measurement of a Single Blood Cell Surface Antigen by Thermal Lens Microscopy

2000 ◽  
Vol 283 (1) ◽  
pp. 27-32 ◽  
Author(s):  
Hiroko Kimura ◽  
Fumiko Nagao ◽  
Asako Kitamura ◽  
Kazuya Sekiguchi ◽  
Takehiko Kitamori ◽  
...  
Keyword(s):  
Cell Surface ◽  
Blood Cell ◽  
Surface Antigen ◽  
Thermal Lens ◽  
Cell Surface Antigen ◽  
Thermal Lens Microscopy

A new mouse cell-surface antigen (Ly-m18) defined by a monoclonal antibody

1981 ◽  
Vol 13 (6) ◽  
pp. 547-554 ◽  
Author(s):  
Shoji Kimura ◽  
Nobuhiko Tada ◽  
Yen Liu ◽  
Ulrich H�mmerling
Keyword(s):  
Monoclonal Antibody ◽  
Cell Surface ◽  
Surface Antigen ◽  
Mouse Cell ◽  
Cell Surface Antigen

Recent advances in trophoblast cell‐surface antigen 2 targeted therapy for solid tumors

2021 ◽  
Author(s):  
Shutan Liao ◽  
Bing Wang ◽  
Rong Zeng ◽  
Haifeng Bao ◽  
Xiaomin Chen ◽  
...  
Keyword(s):  
Targeted Therapy ◽  
Cell Surface ◽  
Solid Tumors ◽  
Surface Antigen ◽  
Trophoblast Cell ◽  
Cell Surface Antigen ◽  
Recent Advances

scholarly journals AU cell-surface antigen of human malignant melanoma: solubilization and partial characterization.

1979 ◽  
Vol 76 (6) ◽  
pp. 2898-2902 ◽  
Author(s):  
T. E. Carey ◽  
K. O. Lloyd ◽  
T. Takahashi ◽  
L. R. Travassos ◽  
L. J. Old
Keyword(s):  
Malignant Melanoma ◽  
Cell Surface ◽  
Surface Antigen ◽  
Cell Surface Antigen ◽  
Partial Characterization ◽  
Human Malignant Melanoma

scholarly journals Expression of a developmentally regulated antigen on the surface of skeletal and cardiac muscle cells.

1985 ◽  
Vol 100 (6) ◽  
pp. 1977-1987 ◽  
Author(s):  
S J Kaufman ◽  
R F Foster ◽  
K R Haye ◽  
L E Faiman
Keyword(s):  
Cell Surface ◽  
Cardiac Muscle ◽  
Surface Antigen ◽  
Cardiac Cells ◽  
Cell Surface Antigen ◽  
Myoblast Differentiation ◽  
Specific Cell ◽  
Developmentally Regulated ◽  
Cardiac Muscle Cells ◽  
Species Specific

H36 is a species-specific, cell-surface antigen on differentiating newborn rat skeletal myoblasts and myogenic lines. This membrane antigen has been defined by a monoclonal antibody raised by the fusion of SP 2/0-Ag14 myeloma cells with spleen cells from mice immunized with myotubes derived from the myogenic E63 line. H36 antigen, isolated by immunoaffinity chromatography, is comprised of two polypeptides with apparent molecular weights of 98,000 and 117,000. Fluorescence photometry and radioimmunoassays have been used to follow quantitative and topographic changes in the H36 determinant during myogenesis. H36 is present at a basal level on replicating myoblasts; it increases on prefusion myoblasts and persists on myotubes. At or near the time of prefusion, it becomes concentrated between adjacent aligned myoblasts and localized on membrane "blebs". H36 is present on both skeletal and cardiac cells but absent from a variety of cells that include fibroblasts, neuronal cells, and smooth muscle. There are approximately 4 x 10(5) determinants per myoblast, and the Ka of the antibody is 3.8 x 10(8) liters/mol. The distributions of H36 on the top and attached surfaces of myoblasts and myotubes are distinct, which suggests localized specialization of these surfaces. H36 is an integral membrane component and upon cross-linking, it associates with the detergent-insoluble cytoskeletal framework. Inhibition of myogenesis by 5-bromodeoxyuridine or by calcium deprivation prevents the developmentally associated changes in the expression of H36. H36 is also absent or markedly reduced on the fu- and Ama102 developmentally defective mutant myoblast lines. We conclude that H36 is a muscle-specific, developmentally regulated cell-surface antigen that may have a role in myoblast differentiation and that can be used to determine the embryonic lineages of skeletal and cardiac muscle.

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