Antioxidant stoichiometry and the oxidative fate of vitamin E in peroxyl radical scavenging reactions

Lipids ◽  
1995 ◽  
Vol 30 (9) ◽  
pp. 789-793 ◽  
Author(s):  
Daniel C. Liebler ◽  
Jeanne A. Burr
1990 ◽  
Vol 9 ◽  
pp. 28
Author(s):  
Valerian Kagan ◽  
Elena Serbinova ◽  
Derick Han ◽  
Anna Shvedova ◽  
Lester Packer

2010 ◽  
Vol 140 (2) ◽  
pp. 127-138 ◽  
Author(s):  
B. Santhosh Kumar ◽  
Amit Kunwar ◽  
Beena G. Singh ◽  
Adeel Ahmad ◽  
K. Indira Priyadarsini

1998 ◽  
Vol 76 (4) ◽  
pp. 661-664 ◽  
Author(s):  
J Wu ◽  
H Sugiyama ◽  
L -H Zeng ◽  
D Mickle ◽  
T -W Wu

The peroxidation of human erythrocytes induced by peroxyl radical initiator and its inhibition by several gallate esters (e.g., propyl, methyl, ethyl) and Trolox (a more polar analogue of vitamin E) have been studied. The antioxidant activity was determined on erythrocytes against hemolysis generated by a thermal activator, 2,2prime-azobis-(2-amidinopropane)dihydrogenchloride. It was found that propyl gallate and its two analogues were more effective than Trolox in preventing cell lysis. However, the combination of gallate esters and Trolox produced a protective effect exceeding the arithmetic sum of their individual contributions. These perceived synergisms occur at more than one level of Trolox at a given level of a gallate ester.Key words: Trolox, gallates, synergism, peroxyl radicals.


1997 ◽  
Vol 52 (11-12) ◽  
pp. 828-833 ◽  
Author(s):  
Purusotam Basnet ◽  
Tetsuya Matsuno ◽  
Richard Neidlein

Abstract We evaluated free radical scavenging activity of the water, methanol and chloroform ex­tracts of propolis in 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical and xanthine-xanthine oxidase (XOD) generated superoxide anion assay systems. The free radical scavenging activity guided fractionation and chemical analysis led to the isolation of a new compound, propol {3-[4-hydroxy-3-(3-oxo-but-1-enyl)-phenyl]-acrylic acid) from the water extract, which was more potent than most common antioxidants such as vitamin C and vitamin E (α-tocopherol) in these assay systems.


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