Effects of one-year treatment with estrogens on bone mass, intestinal calcium absorption, and 25-hydroxyvitamin D-1α-hydroxylase reserve in postmenopausal osteoporosis

1988 ◽  
Vol 42 (2) ◽  
pp. 77-86 ◽  
Author(s):  
Roberto Civitelli ◽  
Donato Agnusdei ◽  
Paolo Nardi ◽  
Fabio Zacchei ◽  
Louis V. Avioli ◽  
...  
1977 ◽  
Vol 86 (4) ◽  
pp. 784-793 ◽  
Author(s):  
Gerd Offermann ◽  
Dieter Kraft

ABSTRACT Five patients with chronic post-operative hypoparathyroidism were treated with 450 μg/day 5,6-trans-25-hydroxyvitamin D3 (5,6-trans-25OHD3) for 14 days, and the treatment was continued with 150 μg/day for one year. At the end of this period the patients received 450 μg/day 5,6-cis-25-hydroxyvitamin D3 (5,6-cis-25OHD3) for 14 days. Comparison of the effects of both isomers revealed a similar ability to enhance intestinal calcium absorption and to normalize serum calcium; serum phosphate and alkaline phosphatase, however, remained unaffected. Urinary phosphate and hydroxyproline excretion decreased on the cis-isomer and increased on the trans-isomer. During treatment with the lower dose of 5,6-trans-25OHD3 intestinal calcium absorption remained in the normal range for one year, whereas the serum calcium decreased to the levels observed before administration of 450 μg/day within 6 weeks. The results suggest that in hypoparathyroidism 5,6-cis-25OHD3 and 5,6-trans-25OHD3 are equally effective on serum calcium and on intestinal calcium absorption, but that their mode of action on renal phosphate handling and on calcium release from bone is different.


2014 ◽  
Vol 33 (3) ◽  
pp. 319-328 ◽  
Author(s):  
Marília Brasilio Rodrigues Camargo ◽  
Tatiane Vilaça ◽  
Lilian Fukusima Hayashi ◽  
Olguita G. Ferreira Rocha ◽  
Marise Lazaretti-Castro

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Kátia Josiany Segheto ◽  
Leidjaira Lopes Juvanhol ◽  
Danielle Cristina Guimarães da Silva ◽  
Cristiane Junqueira de Carvalho ◽  
Fernanda Hansen ◽  
...  

2013 ◽  
Vol 16 (1) ◽  
pp. 110-117 ◽  
Author(s):  
Theodora Mouratidou ◽  
German Vicente-Rodriguez ◽  
Luis Gracia-Marco ◽  
Inge Huybrechts ◽  
Isabelle Sioen ◽  
...  

2014 ◽  
Vol 73 (Suppl 2) ◽  
pp. 760.2-760
Author(s):  
B. Seriolo ◽  
R. Brizzolara ◽  
S. Soldano ◽  
A. Casabella ◽  
L. Molfetta ◽  
...  

Bone ◽  
2009 ◽  
Vol 44 (1) ◽  
pp. 168-172 ◽  
Author(s):  
Tatsuhiko Kuroda ◽  
Masataka Shiraki ◽  
Shiro Tanaka ◽  
Hiroaki Ohta

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