On-line estimation of lactic acid concentration by conductivity measurement in fermentation broth

1997 ◽  
Vol 11 (1) ◽  
pp. 17-20 ◽  
Author(s):  
T. Payot ◽  
M. Fick
2013 ◽  
Vol 19 (No. 2) ◽  
pp. 73-80 ◽  
Author(s):  
V. Hábová ◽  
K. Melzoch ◽  
M. Rychtera ◽  
L. Přibyl ◽  
V. Mejta

The paper deals with the possibility of using two-stage electrodialysis for recovery of lactic acid from model solutions and from fermentation broth. In the first step lactate was concentrated with desalting electrodialysis using ion exchange membranes Ralex (Mega,Czech Republic). The highest final concentration of 111 g/l was reached in the concentrate, it means an increase more than 2.5-times in comparison with the initial concentration. At the most 2 g of lactate per litre remained in the feed. The second step was the electroconversion of sodium lactate to lactic acid by water-splitting electrodialysis with the bipolar membranes Neosepta (Tokuyama Corp.,Japan). The final lactic acid concentration of 157 g/l was reached in the diluate. Total required energy in both electrodialysis processes consisting of the energy consumption for lactate transfer and for its electroconversion to lactic acid was 142 Wh/mol. The fermentation broth was decolourised before electrodialysis experiments. The best decolourisation capacity was shown by granulated active charcoal filled in the column operated by a slow flow of broth.


1958 ◽  
Vol 192 (3) ◽  
pp. 577-580 ◽  
Author(s):  
Donald D. Van Fossan ◽  
Robert T. Clark

Simulated altitude exposure elevates the postmortem brain lactic acid concentration up to 98 mg/100 gm above controls depending on species used, duration, and intensity of exposure. The sharp difference in post-mortem brain lactic acid concentration between altitude exposed animals and controls remains demonstrable for the longest postmortem intervals studied (20 hr. in the dog, 30 hr. in the rabbit, and 6 hr. in the rat). Upon recovery from altitude exposure the brain lactic acid and/or precursors return toward pre-exposure levels in accordance with first order reaction kinetics during the first few minutes. The velocity constant is .32 and the half-life is 2.2 minutes. Elevated post-mortem brain lactic acid concentration is a constant finding in animals which were hypoxic at the time of death and appears to be a suitable criterion for establishing ante-mortem altitude exposure or other physiologically similar oxygen deficiency situations.


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