scholarly journals Session - 4 December 20, 2007 Evidence based laboratory medicine

2007 ◽  
Vol 22 (S2) ◽  
pp. 176-181
Keyword(s):  
Laboratory Medicine ◽  
Evidence Based

Laboratory Medicine: Reference Values and Evidence-Based Medicine

Neonatology ◽  
2018 ◽  
pp. 2429-2432
Author(s):  
Mariangela Longini ◽  
Fabrizio Proietti ◽  
Francesco Bazzini ◽  
Elisa Belvisi
Keyword(s):  
Reference Values ◽  
Evidence Based Medicine ◽  
Laboratory Medicine ◽  
Evidence Based ◽  
Based Medicine

New laboratory markers for the management of rheumatoid arthritis patients

2014 ◽  
Vol 0 (0) ◽  
Author(s):  
Daniela P. Foti ◽  
Marta Greco ◽  
Eleonora Palella ◽  
Elio Gulletta
Keyword(s):  
Rheumatoid Arthritis ◽  
Early Diagnosis ◽  
Health Problem ◽  
Laboratory Medicine ◽  
Social Health ◽  
Evidence Based ◽  
Pathogenetic Mechanism ◽  
Autoimmune Rheumatic Diseases ◽  
Laboratory Markers ◽  
Laboratory Biomarkers

AbstractRheumatoid arthritis, the most prominent of systemic autoimmune rheumatic diseases, represents an important social health problem. Recent insights into the immunopathogenic mechanism of this complex and multiform illness might open new perspectives for a more appropriate laboratory approach. In this review we focus on the most relevant pathogenetic mechanism; indicating the laboratory biomarkers specifically linked to early diagnosis, prognosis, evolutive aspects of the disease, and therapeutic efficacy. Evidence based on laboratory medicine could provide the best outcome for patients.

scholarly journals Evidence-Based Laboratory Medicine: How Well Do Laboratories Follow Recommendations and Guidelines? The Cardiac Marker Guideline Uptake in Europe (CARMAGUE) Study

2012 ◽  
Vol 58 (1) ◽  
pp. 305-306 ◽  
Author(s):  
Paul O Collinson ◽  
Marja P van Dieijen-Visser ◽  
Kari Pulkki ◽  
Angelika Hammerer-Lercher ◽  
Janne Suvisaari ◽  
...  
Keyword(s):  
Laboratory Medicine ◽  
Evidence Based ◽  
Cardiac Marker

scholarly journals The role of evidence-based laboratory medicine in health service

2002 ◽  
Vol 21 (3) ◽  
pp. 245-254 ◽  
Author(s):  
Nada Majkic-Singh
Keyword(s):  
Health Care ◽  
Clinical Experience ◽  
Evidence Based Medicine ◽  
Laboratory Tests ◽  
Laboratory Medicine ◽  
Systematic Research ◽  
Evidence Based ◽  
External Evidence ◽  
Based Medicine ◽  
The Impact

Evidence-based laboratory medicine (EBLM) is the use of the current best evidence of the utility of laboratory tests in making decisions about the care of individual patients. This practice means integrating laboratory and clinical experience with the last available external evidence from systematic research. It means that the definition of EBLM focuses on two key elements: experience and evidence from systematic research. Although the term evidence-based medicine (EBM) was created in Canada at Mc Master University by a group lad by Dr Gard Guyatt, there are various claims as to the origin of its practice. Regardless of its origins, many factors have come together over the past 30 years to drive the movement to EBM. One factor is those individual physicians, faced with numerous medical informations; the second factor is the global phenomenon of increasing health care costs and third is that patients who have generally more education, want the best in diagnostics and therapies. It means that evidence-based medicine has been driven by the need to cape with information overload, by costcontrol, and by public impatient for the best in diagnostics and treatment. Clinical guidelines care maps, and outcome measures are quality improvement tools for the appropriateness, efficiency and effectiveness of health services. Laboratory professionals must direct more effort to demonstrating the impact of laboratory tests on a greater variety of clinical outcomes. Evidence-based laboratory medicine aims to advise clinical diagnosis and management of disease through systematic researching and disseminating generalisible new knowledge that meets the standard of critical review on clinically effective practice of laboratory investigations. In laboratory medicine, the use of tests increases; new tests are constantly introduced, but "old" tests are seldom removed from the repertoire. This, together with limited public funds for the health care should underline the challenge for laboratory professionals to provide evidence for the utility of different tests. This practice means integrating laboratory and clinical experience with the best available external evidence from systematic research therefore, it is important that advice given by laboratory medicine professionals are sound and based on evidence in the pre-analytical, analytical, and post-analytical phases of the diagnostic process. This paper provides an insight into the rationale, methodology and the phases of the EBLM.

scholarly journals Overview of Evidence-based Medicine: Challenges for Evidence-based Laboratory Medicine

2001 ◽  
Vol 47 (8) ◽  
pp. 1536-1546 ◽  
Author(s):  
Matthew J McQueen
Keyword(s):  
Evidence Based Medicine ◽  
Information Overload ◽  
Clinical Information ◽  
Laboratory Medicine ◽  
Evidence Based ◽  
Efficiency And Effectiveness ◽  
Care Maps ◽  
Critical Appraisal Skills ◽  
Based Medicine ◽  
The Impact

Abstract Evidence-based medicine (EBM) has been driven by the need to cope with information overload, by cost-control, and by a public impatient for the best in diagnostics and treatment. Clinical guidelines, care maps, and outcome measures are quality improvement tools for the appropriateness, efficiency, and effectiveness of health services. Although they are imperfect, their value increases with the quality of the evidence they incorporate. Laboratory professionals must direct more effort to demonstrating the impact of laboratory tests on a greater variety of clinical outcomes. Laboratory and clinical practitioners must be familiar with many of the accessible electronic and paper tools for searching for evidence. Detailed statistical and epidemiologic knowledge is not essential, but critical appraisal skills and a competent understanding of the strengths and weaknesses of systematic review and metaanalysis are necessary. Overemphasis on complexity and failure to recognize time limitations are major barriers to translating EBM into everyday practice. Emphasizing and practicing the role of the laboratory professional as a skilled clinical consultant strongly grounded in evidence as well, in addition to better integration of laboratory and clinical information and improved laboratory reports will overcome most barriers. There is a poverty of good, primary studies of test evaluations. Institution of more consistent standards for the design and reporting of studies on diagnostic accuracy should improve the situation. If nothing else, systematic reviews have demonstrated the need for more good-quality primary research in laboratory medicine.

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