Prevalence of abnormal thyroid function tests in a Down’s syndrome population

1997 ◽  
Vol 166 (2) ◽  
pp. 80-82 ◽  
Author(s):  
S. Rooney ◽  
E. Walsh
1978 ◽  
Vol 88 (1) ◽  
pp. 48-54 ◽  
Author(s):  
S. Korsager ◽  
E. M. Chatham ◽  
H. P. Østergaard Kristensen

ABSTRACT Thyroid status was studied in 24 patients above the age of 40 years with Down's syndrome. Three patients had thyroid function tests indicating hypothyroidism. Eight patients had thyroid autoantibodies in serum and 8 patients had a higher than normal level of thyroid stimulating hormone in serum. None of the patients had figures indicating thyrotoxicosis. None of the patients showed any of the clinical signs usually seen in patients with hypothyroidism. It is concluded that biochemical tests indicating hypothyroidism are much more often seen in patients with Down's syndrome than in normal subjects and that thyroid status should be assessed in old patients with this disease.


1988 ◽  
Vol 153 (1) ◽  
pp. 102-104 ◽  
Author(s):  
Chinta Mani

Fifty-five adult Down's syndrome subjects resident at Northgate Hospital were screened for the presence of thyroid dysfunction. Approximately 50% of the subjects had clinical features suggestive of hypothyroidism, sufficient to require thyroid-function tests. Twenty-two per cent of the total suffered from some degree of hypothyroidism, and 16% had positive antibodies to thyroid tissue.


2019 ◽  
Author(s):  
Catriona Hilton ◽  
Farhan Ahmed ◽  
Asif Ali

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