Quantitative analysis of myelinated nerve fibers of peripheral nerve in streptozotocin-induced diabetes mellitus

1995 ◽  
Vol 25 (2-3) ◽  
Author(s):  
Eva Ochodnická ◽  
Milan Ochodnický ◽  
Kamil Belej ◽  
Eva Füseková ◽  
Ludmila Bošel’ová
Keyword(s):  
Diabetes Mellitus ◽  
Quantitative Analysis ◽  
Peripheral Nerve ◽  
Nerve Fibers ◽  
Myelinated Nerve ◽  
Myelinated Nerve Fibers ◽  
Streptozotocin Induced Diabetes

scholarly journals THE ULTRASTRUCTURE OF ADULT VERTEBRATE PERIPHERAL MYELINATED NERVE FIBERS IN RELATION TO MYELINOGENESIS

1955 ◽  
Vol 1 (4) ◽  
pp. 271-278 ◽  
Author(s):  
J. David Robertson
Keyword(s):  
Electron Microscope ◽  
Schwann Cell ◽  
Cell Surface ◽  
Peripheral Nerve ◽  
Myelin Sheath ◽  
Nerve Fibers ◽  
Myelinated Nerve ◽  
Thin Sections ◽  
Double Membrane ◽  
Myelinated Nerve Fibers

Adult chameleon myelinated peripheral nerve fibers have been studied with the electron microscope in thin sections. The outer lamella of the myelin sheath has been found to be connected as a double membrane to the surface of the Schwann cell. The inner lamella is connected as a similar double membrane with the double axon-Schwann membrane. The relations of these double connecting membranes suggest that the layered myelin structure is composed of a double membrane which is closely wound about the axon as a helix. These findings support the new theory of myelinogenesis proposed recently by Geren. The possible significance of these results with respect to cell surface membranes and cytoplasmic double membranes is discussed.

α-Melanocyte-stimulating hormone stimulates the outgrowth of myelinated nerve fibers after peripheral nerve crush

1986 ◽  
Vol 92 (2) ◽  
pp. 451-454 ◽  
Author(s):  
J. Verhaagen ◽  
P.M. Edwards ◽  
F.G.I. Jennekens ◽  
P. Schotman ◽  
W.H. Gispen
Keyword(s):  
Peripheral Nerve ◽  
Nerve Fibers ◽  
Nerve Crush ◽  
Myelinated Nerve ◽  
Myelinated Nerve Fibers ◽  
Melanocyte Stimulating Hormone ◽  
Stimulating Hormone

scholarly journals Evaluation of dermal myelinated nerve fibers in diabetes mellitus

2013 ◽  
Vol 18 (2) ◽  
pp. 162-167 ◽  
Author(s):  
Amanda C. Peltier ◽  
M. Iliza Myers ◽  
Kay J. Artibee ◽  
Audra D. Hamilton ◽  
Qing Yan ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Nerve Fibers ◽  
Myelinated Nerve ◽  
Myelinated Nerve Fibers

scholarly journals THE SUBMICROSCOPIC ORGANIZATION OF AXON MATERIAL ISOLATED FROM MYELIN NERVE FIBERS

1953 ◽  
Vol 98 (3) ◽  
pp. 269-276 ◽  
Author(s):  
E. De Robertis ◽  
C. M. Franchi
Keyword(s):  
Electron Microscopy ◽  
Electron Microscope ◽  
Phase Contrast ◽  
Nerve Fibers ◽  
Myelinated Nerve ◽  
Myelinated Nerve Fibers ◽  
Dense Granules ◽  
Small Clusters ◽  
Membranous Material ◽  
The Way

A technique has been developed for the extrusion of axon material from myelinated nerve fibers. This material is then compressed and prepared for observation with the electron microscope. All the stages of preparation and purification of the axon material can be checked microscopically and in the present paper they are illustrated with phase contrast photomicrographs. Observation with the electron microscope of the compressed axons showed the presence of the following components: granules, fibrils, and a membranous material. Only the larger granules could be seen with the ordinary microscope. A considerable number of dense granules were observed. Of these the largest resemble typical mitochondria of 250 mµ by 900 mµ. In addition rows or small clusters of dense granules ranging in diameter from 250 to 90 mµ were present. In several specimens fragments of a membrane 120 to 140 A thick and intimately connected with the axon were found. The entire axon appeared to be constituted of a large bundle of parallel tightly packed fibrils among which the granules are interspersed. The fibrils are of indefinite length and generally smooth. They are rather labile structures, less resistant in the rat than in the toad nerve. They varied between 100 and 400 A in diameter and in some cases disintegrated into very fine filaments (less than 100 A thick). The significance is discussed of the submicroscopic structures revealed by electron microscopy of the material prepared in the way described.

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