scholarly journals Wound healing of autologous implants in the nasal septal cartilage —a verwoerd study

1997 ◽  
Vol 49 (1) ◽  
pp. 80-81
Author(s):  
D. S. Grewal ◽  
Dinaz K. Irani
Keyword(s):  
Wound Healing ◽  
Septal Cartilage ◽  
Nasal Septal Cartilage

Wound Healing of Autologous Implants in the Nasal Septal Cartilage

ORL ◽  
1991 ◽  
Vol 53 (5) ◽  
pp. 310-314 ◽  
Author(s):  
C.D.A. Verwoerd ◽  
H.L. Verwoerd-Verhoef ◽  
C.A. Meeuwis ◽  
R.O. van der Heul
Keyword(s):  
Wound Healing ◽  
Septal Cartilage ◽  
Nasal Septal Cartilage

scholarly journals Polydispersity in Sulfation Profile of Oligosaccharide Alditols Isolated from the Protein-Linkage Region and the Repeating Disaccharide Region of Chondroitin 4-Sulfate of Bovine Nasal Septal Cartilage

1996 ◽  
Vol 240 (3) ◽  
pp. 789-797 ◽  
Author(s):  
Tonny Beer ◽  
Atsuko Inui ◽  
Hiromi Tsuda ◽  
Kazuyuki Sugahara ◽  
Johannes F. G. Vliegenthart
Keyword(s):  
Septal Cartilage ◽  
Linkage Region ◽  
Nasal Septal Cartilage

Skull growth in achondroplasic (cn) mice; a craniometric study

Development ◽  
1975 ◽  
Vol 33 (4) ◽  
pp. 1013-1022
Author(s):  
Rosemary J. Jolly ◽  
W. J. Moore
Keyword(s):  
Cranial Base ◽  
Septal Cartilage ◽  
Skull Morphology ◽  
Condylar Cartilage ◽  
Central Section ◽  
Condylar Process ◽  
Skull Growth ◽  
Anterior Extension ◽  
Posterior Extension ◽  
Nasal Septal Cartilage

Skull morphology in achondroplasic (cn/cn) mice was compared with that of normal siblings in order to determine the effects of this chondrodystrophy on skull growth, particular attention being given to dimensions reflecting growth at the synchondroses of the cranial base, the nasal septal cartilage and the condylar cartilage of the mandible. The central section of the cranial base (basicranial axis) was reduced by 25 %, the length of the viscerocranium by 18 % and the length of the condylar process by 11 %. The evidence indicates that these reductions are due to diminished growth at respectively the spheno-occipital and midsphenoidal synchondroses, the nasal septal cartilage and the condylar cartilage. The relative sizes of the reductions in cranial base, viscerocranium and condylar process suggest that the growth of synchondrotic and septal cartilages is diminished to a greater extent than that of condylar cartilage. This finding is in agreement with the observations that condylar cartilage, unlike synchondrotic and septal cartilage, grows by surface apposition and that the principal defect in cn/cn mice is a disturbance of interstitial cartilaginous growth. The posterior extension of the basicranial axis of the cn/cn mice was reduced by 14 % and the anterior extension by 2 %. The width of the cranial base was decreased by 9 % and the angle between the basicranial axis and its anterior extension was decreased by 3 %. The length of theneurocranium was reduced by 19 % in the cn/cn animals while the volume of the endocranial cavity was diminished by only 18 %. The latter reduction is less than would be expected from the cube relationship between volume and linear dimensions but is readily accounted for by the lack of reduction in the height or width of the neurocranium, the slight flattening of the cranial base and the doming of the neurocranial vault.

Wound Healing of KTP and Argon Laser Lesions in the Canine Nasal Cavity

1993 ◽  
Vol 108 (3) ◽  
pp. 283-292 ◽  
Author(s):  
Ilsa Schwartz ◽  
Edward G. Kass ◽  
Bruce M. Massaro ◽  
Richard A. Komorowski ◽  
Robert J. Toohill
Keyword(s):  
Wound Healing ◽  
Laser Energy ◽  
Argon Laser ◽  
Septal Cartilage ◽  
Respiratory Epithelium ◽  
Sinus Surgery ◽  
Coagulation Necrosis ◽  
Nasal Tissue ◽  
Wide Range ◽  
Argon Lasers

The potassium titanyl phosphate (KTP) and argon lasers are increasingly used in nasal and sinus surgery. Histologic effects of these lasers on living nasal tissue have not been investigated. Sixteen dogs underwent laser nasal surgery (eight for each laser). Flexible fiberoptic quartz fibers were used with both lasers to deliver the laser energy to the tissue. The dogs were allowed to heal and then underwent biopsy at 3, 7, 21, and 90 days postoperatively. The argon and KTP lasers had similar tissue effects. Histologically, a thin rim of coagulation necrosis and acute inflammation were seen at 3 days postoperatively. By 7 days, fibroblasts and granulation tissue were observed. At 21 days, fibroblast proliferation and re-epithelialization with respiratory epithelium were the predominant findings. Finally, at 90 days postoperatively, respiratory epithelium and submucosal structures were found overlying a plug of scar filling the defect in the septal cartilage. This healing was consistent through a wide range of energy densities. These lasers are easily used with sinus endoscopes and the operating microscope to allow access to difficult areas. These factors and the wound-healing characteristics noted in this study would seem to make them suited for use in rhinologic surgery.

scholarly journals Cellular proliferation in the nasal septal cartilage of juvenile minipigs

2014 ◽  
Vol 225 (6) ◽  
pp. 604-613 ◽  
Author(s):  
Ayman A. Al Dayeh ◽  
Susan W. Herring
Keyword(s):  
Cellular Proliferation ◽  
Septal Cartilage ◽  
Nasal Septal Cartilage

Tissue Engineered Human Septal Cartilage in a Murine Model

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P87-P88
Author(s):  
Angela Chang ◽  
Sage August ◽  
Barbara L Schumacher ◽  
Williams Gregory ◽  
Robert L Sah ◽  
...  
Keyword(s):  
Cell Viability ◽  
Murine Model ◽  
Three Dimensional ◽  
Alginate Beads ◽  
Septal Cartilage ◽  
Hematoxylin And Eosin ◽  
Matrix Production ◽  
Nasal Septal Cartilage

Problem Tissue engineering of human nasal septal cartilage represents an alternative technique for creating large quantities of autologous material for use in reconstructive surgery of the head and neck. Septal neocartilage constructs developed in vitro by the alginate method have demonstrated cartilaginous extracellular matrix production, but their biocompatibility and development in vivo remains largely unknown. Methods A murine model was used to examine the behavior of neocartilage constructs in vivo. Chondrocytes collected from donors undergoing septoplasty were expanded in monolayer and suspended in alginate beads for three-dimensional culture in media containing human serum and growth factors. After in vitro incubation for 5 weeks, the neocartilage constructs were implanted subcutaneously in the dorsum of athymic mice for 30 days (n=3). The mice were sacrificed and the constructs were explanted for assessment of cell viability, gross morphology, and histology. Results The mice survived and tolerated the implant well. Infection and extrusion were not observed. Neocartilage constructs maintained their general shape and size, and demonstrated cell viability after implantation. Explanted constructs were firm and opaque, sharing closer semblance to native septal tissue relative to the gelatinous, translucent pre-implant constructs. On hematoxylin and eosin staining, the explanted constructs exhibited distinct morphologies characteristic of native tissue, which were not observed in pre-implant constructs. Conclusion Neocartilage constructs are viable in an in vivo murine model. The morphologic and histologic features of explanted constructs more closely resemble native septal tissue when compared to pre-implant constructs. Significance Septal neocartilage constructs are biocompatible and demonstrate potential for in vivo maturation with eventual clinical application.

The width of nasal septal cartilage

2003 ◽  
Vol 129 (2) ◽  
pp. P256-P257
Author(s):  
A Ross
Keyword(s):  
Septal Cartilage ◽  
Nasal Septal Cartilage

scholarly journals Endoscopic Tympanoplasty Using Nasal Septal Cartilage Allograft

2017 ◽  
Vol 69 (2) ◽  
pp. 199-203 ◽  
Author(s):  
N. Ahilasamy ◽  
Badra Shanti ◽  
Sivaprakasam Rajasekaran
Keyword(s):  
Septal Cartilage ◽  
Nasal Septal Cartilage ◽  
Endoscopic Tympanoplasty
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