Increased FDG uptake in the wall of the right atrium in people who participated in a cancer screening program with whole-body PET

1999 ◽  
Vol 13 (1) ◽  
pp. 55-59 ◽  
Author(s):  
Hirofumi Fujii ◽  
Michiru Ide ◽  
Seiei Yasuda ◽  
Wakoh Takahashi ◽  
Akira Shohtsu ◽  
...  
2018 ◽  
Vol 27 (5) ◽  
pp. 1501-1512 ◽  
Author(s):  
Boqia Xie ◽  
Bi-Xi Chen ◽  
Jiao-Yan Wu ◽  
Xingpeng Liu ◽  
Min-Fu Yang

Abstract Background This retrospective study was designed to explore the factors relevant to increased atrial 18F-fluorodeoxyglucose (FDG) uptake in patients with atrial fibrillation (AF) who had undergone routine whole-body positron emission tomography/computed tomography (PET/CT) imaging. Methods and Results Forty-eight consecutive AF patients (32 persistent, 16 paroxysmal) were identified from our routine FDG PET/CT database. Twenty-two control subjects were selected to establish the normal range of FDG uptake (maximum standardized uptake value, SUVmax) in target tissues. A target-to-background ratio (TBR) was calculated to determine abnormal uptake in the atrium and atrial appendage (AA). Univariate comparisons and multivariate regression analyses were conducted to explore the factors associated with the increased FDG accumulation in the atrium and AA. Seventeen AF patients, all with persistent AF, had increased atrial FDG uptake. Most of them (14, or 82.4%) had increased uptake in the right atrium. Eleven AF patients, 9 with persistent AF, had increased uptake in the AA, and bilateral AAs were equally involved. Multivariate logistic regression analyses identified that female gender, persistent AF, and activity in epicardial adipose tissue (EAT) were independent factors predicting the increased activity of the atrium; also, SUVmax of the left ventricle was found for the AA. In addition, multivariate linear regression analyses showed that EAT activity was the only independent variable linearly correlated with the activity of the atrium and AA. Conclusions Atrial uptake was present in persistent AF and localized mainly in the right atrium, whereas bilateral AAs could be equally involved. Multiple factors contributed to the increased activity in atrium; in particular, the EAT activity was independently correlated with the activity of the atrium and AA.


2018 ◽  
Vol 28 (2) ◽  
pp. 193-195 ◽  
Author(s):  
Sanja Borozan ◽  
Ljiljana Vuckovic ◽  
Brigita Smolovic

Objective: To present a case of colopathy related to the use of diclofenac in a patient with a positive immunochemical faecal occult blood test (iFOBT) and to discuss the influence of nonsteroidal anti-inflammatory drugs (NSAIDs) on iFOBT specificity. Clinical Presentation and Intervention: A colonoscopy in a 56-year-old female presenting with a positive iFOBT revealed diaphragm-like strictures and ulcers in the right colon. While carrying out a detailed retrospective interview, she reported a chronic backache requiring long-term NSAID treatment. Conclusion: No association has been established between chronic use of NSAID and a false-positive iFOBT. There is no need to stop NSAIDs before performing an iFOBT in a colorectal cancer screening program.


2021 ◽  
Vol 18 (1) ◽  
pp. 140-147 ◽  
Author(s):  
Yoshimi Anzai ◽  
Sadahiko Nishizawa ◽  
Tomomi Shinke ◽  
Shota Takesono ◽  
Toshiko Asai ◽  
...  

2008 ◽  
Vol 149 (32) ◽  
pp. 1491-1498 ◽  
Author(s):  
Imre Boncz ◽  
Andor Sebestyén ◽  
Lajos Döbrőssy ◽  
Zoltán Péntek ◽  
Attila Kovács ◽  
...  

Célkitűzés: Az országos kiterjedésű, szervezett emlőszűrési program 2002 januárjában indult el Magyarországon a 45–65 év közötti nők számára 2 éves szűrési intervallummal. A dolgozat célja a szervezett emlőszűrési program részvételi mutatóinak meghatározása, beleértve a szűrési és diagnosztikus célú képalkotó emlőfelvételek gyakoriságának elemzését. Adatok és módszerek: Az elemzésben szereplő adatok az Országos Egészségbiztosítási Pénztár finanszírozási adatbázisából származnak, és a 2000–2005 közötti 6 évet ölelik fel. A 45–65 éves nők körében meghatározták azok arányát, akik a szervezett szűrést megelőző két évben (2000–2001), illetve a program első két ciklusában (2002–2003, 2004–2005) akár szűrési, akár diagnosztikai célú képalkotó emlővizsgálaton vettek részt. Eredmények: A szűrési célú képalkotó emlőfelvételen részt vettek aránya (átszűrtség) a 2000–2001-es 7,4%-ról a 2002–2003-as, illetve 2004–2005-ös szervezett emlőszűrési ciklusban 34,0, illetve 29,5%-ra emelkedett. A diagnosztikus célú képalkotó emlőfelvételen részt vettek aránya (átvizsgáltság) pedig ugyanezen időszakokban 19,8%-ról 22,1 (2002–2003), illetve 23,2%-ra (2004–2005) emelkedett. Az országos lefedettség (átszűrtség + átvizsgáltság) ennek megfelelően a szervezett szűrés hatására 26,2%-ról (2000–2001) 53,5%-ra (2002–2003), illetve 50,8%-ra (2004–2005) nőtt a vizsgált kétéves ciklusban a 45–65 év közötti nők esetében. Következtetés: A magyar emlőszűrési program kezdeti részvételi arányai 2004–2005-ben kissé csökkentek; az emlőrák miatti halálozás érdemi csökkentéséhez ennek emelése szükséges.


Cancers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1129
Author(s):  
Audrius Dulskas ◽  
Tomas Poskus ◽  
Inga Kildusiene ◽  
Ausvydas Patasius ◽  
Rokas Stulpinas ◽  
...  

We aimed to report the results of the implementation of the National Colorectal Cancer (CRC) Screening Program covering all the country. The National Health Insurance Fund (NHIF) reimburses the institutions for performing each service; each procedure within the program has its own administrative code. Information about services provided within the program was retrieved from the database of NHIF starting from the 1 January 2014 to the 31 December 2018. Exact date and type of all provided services, test results, date and results of biopsy and histopathological examination were extracted together with the vital status at the end of follow-up, date of death and date of emigration when applicable for all men and women born between 1935 and 1968. Results were compared with the guidelines of the European Union for quality assurance in CRC screening and diagnosis. The screening uptake was 49.5% (754,061 patients) during study period. Participation rate varied from 16% to 18.1% per year and was higher among women than among men. Proportion of test-positive and test-negative results was similar during all the study period—8.7% and 91.3% annually. Between 9.2% and 13.5% of test-positive patients received a biopsy of which 52.3–61.8% were positive for colorectal adenoma and 4.6–7.3% for colorectal carcinoma. CRC detection rate among test-positive individuals varied between 0.93% and 1.28%. The colorectal cancer screening program in Lithuania coverage must be improved. A screening database is needed to systematically evaluate the impact and performance of the national CRC screening program and quality assurance within the program.


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