Synthesis and microphase separation of biodegradable poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) multiblock copolymer films

2008 ◽  
Vol 16 (7) ◽  
pp. 609-613 ◽  
Author(s):  
Jae Ho You ◽  
Sung-Wook Choi ◽  
Jung-Hyun Kim ◽  
Young Tae Kwak
Keyword(s):  
Ethylene Glycol ◽  
Microphase Separation ◽  
Poly Ethylene Glycol ◽  
Copolymer Films ◽  
Multiblock Copolymer ◽  
Biodegradable Poly ◽  
Poly Ethylene

Surface Segregation Assessment In Poly(ε -caprolactone)-poly(ethylene glycol) Multiblock Copolymer Films

2009 ◽  
Vol 10 (3) ◽  
pp. 317-327 ◽  
Author(s):  
Stefania Cometa ◽  
Federica Chiellini ◽  
Irene Bartolozzi ◽  
Emo Chiellini ◽  
Elvira De Giglio ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Surface Segregation ◽  
Poly Ethylene Glycol ◽  
Copolymer Films ◽  
Multiblock Copolymer ◽  
Poly Ethylene

Biodegradable poly(l-lactide)-poly(ethylene glycol) multiblock copolymer: synthesis and evaluation of cell affinity

Biomaterials ◽  
2003 ◽  
Vol 24 (13) ◽  
pp. 2195-2203 ◽  
Author(s):  
Yuqing Wan ◽  
Wenna Chen ◽  
Jian Yang ◽  
Jianzhong Bei ◽  
Shenguo Wang
Keyword(s):  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Multiblock Copolymer ◽  
Biodegradable Poly ◽  
Cell Affinity ◽  
Poly Ethylene

scholarly journals Methoxy-Poly(ethylene glycol) Modified Poly(L-lactide) Enhanced Cell Affinity of Human Bone Marrow Stromal Cells by the Upregulation of 1-Cadherin and Delta-2-catenin

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Xueli Mao ◽  
Zetao Chen ◽  
Junqi Ling ◽  
Jingjing Quan ◽  
Hui Peng ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Cell Adhesion ◽  
Ethylene Glycol ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Marrow Stromal Cells ◽  
Poly Ethylene Glycol ◽  
Copolymer Films ◽  
Cell Affinity ◽  
Poly Ethylene

Poly(l-lactide) (PLLA), a versatile biodegradable polymer, is one of the most commonly-used materials for tissue engineering applications. To improve cell affinity for PLLA, poly(ethylene glycol) (PEG) was used to develop diblock copolymers. Human bone marrow stromal cells (hBMSCs) were cultured on MPEG-b-PLLA copolymer films to determine the effects of modification on the attachment and proliferation of hBMSC. The mRNA expression of 84 human extracellular matrix (ECM) and adhesion molecules was analyzed using RT-qPCR to understand the underlying mechanisms. It was found that MPEG-b-PLLA copolymer films significantly improved cell adhesion, extension, and proliferation. This was found to be related to the significant upregulation of two adhesion genes, CDH1 and CTNND2, which encode 1-cadherin and delta-2-catenin, respectively, two key components for the cadherin-catenin complex. In summary, MPEG-b-PLLA copolymer surfaces improved initial cell adhesion by stimulation of adhesion molecule gene expression.

scholarly journals Three-dimensional fabrication of cell-laden biodegradable poly(ethylene glycol-co-depsipeptide) hydrogels by visible light stereolithography

2015 ◽  
Vol 3 (42) ◽  
pp. 8348-8358 ◽  
Author(s):  
Laura Elomaa ◽  
Chi-Chun Pan ◽  
Yaser Shanjani ◽  
Andrey Malkovskiy ◽  
Jukka V. Seppälä ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Visible Light ◽  
Three Dimensional ◽  
Poly Ethylene Glycol ◽  
Biodegradable Poly ◽  
Poly Ethylene

3D defined cell-laden hydrogel constructs were fabricated using stereolithography and a new biodegradable photocrosslinkable poly(ethylene glycol-co-depsipeptide) prepolymer.

Degradation behavior and biosafety studies of the mPEG–PLGA–PLL copolymer

2016 ◽  
Vol 18 (17) ◽  
pp. 11986-11999 ◽  
Author(s):  
Zelai He ◽  
Ying Sun ◽  
Jun Cao ◽  
Yourong Duan
Keyword(s):  
Ethylene Glycol ◽  
Drug Carrier ◽  
Degradation Behavior ◽  
Poly Ethylene Glycol ◽  
Carrier Material ◽  
Multiblock Copolymer ◽  
New Drug ◽  
Poly Ethylene

In a previous study, a novel biodegradable multiblock copolymer, monomethoxy (poly-ethylene glycol)–poly(d,l-lactide-co-glycolide)–poly(l-lysine) (PEAL), was developed as a new drug carrier material.

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