Contractile properties and protein isoforms of single skeletal muscle fibers from 12- and 30-month-old Fischer 344 Brown Norway F1 hybrid rats

1999 ◽  
Vol 11 (2) ◽  
pp. 109-118 ◽  
Author(s):  
L. V. Thompson
Keyword(s):  
Skeletal Muscle ◽  
Muscle Fibers ◽  
Contractile Properties ◽  
Protein Isoforms ◽  
Brown Norway ◽  
F1 Hybrid ◽  
Fischer 344 ◽  
Skeletal Muscle Fibers

The Adaptive Potential of Skeletal Muscle Fibers

2002 ◽  
Vol 27 (4) ◽  
pp. 423-448 ◽  
Author(s):  
Dirk Pette
Keyword(s):  
Skeletal Muscle ◽  
Fiber Type ◽  
Muscle Fibers ◽  
Protein Isoforms ◽  
Mammalian Skeletal Muscle ◽  
Adaptive Potential ◽  
Hybrid Fibers ◽  
Neuromuscular Activity ◽  
Skeletal Muscle Fibers ◽  
Initial Location

Mammalian skeletal muscle fibers display a great adaptive potential. This potential results from the ability of muscle fibers to adjust their molecular, functional, and metabolic properties in response to altered functional demands, such as changes in neuromuscular activity or mechanical loading. Adaptive changes in the expression of myofibrillar and other protein isoforms result in fiber type transitions. These transitions occur in a sequential order and encompass a spectrum of pure and hybrid fibers. Depending on the quality, intensity, and duration of the alterations in functional demand, muscle fibers may undergo functional transitions in the direction of slow or fast, as well as metabolic transitions in the direction of aerobic-oxidative or glycotytic. The maximum range of possible transitions in either direction depends on the fiber phenotype and is determined by its initial location in the fiber spectrum. Key words: Ca-sequestering proteins, energy metabolism, fiber type transition, myofibrillar protein isofonns, myosin, neuromuscular activity

Krüppel‐like factor 10 regulates the contractile properties of skeletal muscle fibers in mice

2021 ◽  
Author(s):  
Malek Kammoun ◽  
Philippe Pouletaut ◽  
Sandrine Morandat ◽  
Malayannan Subramaniam ◽  
John R. Hawse ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Fibers ◽  
Contractile Properties ◽  
Skeletal Muscle Fibers

scholarly journals Exercise training in late middle-aged male Fischer 344 × Brown Norway F1-hybrid rats improves skeletal muscle aerobic function

2008 ◽  
Vol 93 (7) ◽  
pp. 863-871 ◽  
Author(s):  
Andrew C. Betik ◽  
David J. Baker ◽  
Daniel J. Krause ◽  
Marina J. McConkey ◽  
Russell T. Hepple
Keyword(s):  
Skeletal Muscle ◽  
Exercise Training ◽  
Brown Norway ◽  
Middle Aged ◽  
F1 Hybrid ◽  
Fischer 344 ◽  
Aerobic Function ◽  
Middle Aged Male

Persistent effects of exercise on skeletal muscle glucose transport across the life-span of rats

1993 ◽  
Vol 75 (2) ◽  
pp. 972-978 ◽  
Author(s):  
G. D. Cartee ◽  
C. Briggs-Tung ◽  
E. W. Kietzke
Keyword(s):  
Skeletal Muscle ◽  
Life Span ◽  
Glucose Transport ◽  
Transport Rate ◽  
Brown Norway ◽  
F1 Hybrid ◽  
Fischer 344 ◽  
Glut 4 ◽  
Wide Range ◽  
Muscle Glucose Transport

Very young rats (< 2 mo) have a persistent increase in insulin-stimulated glucose transport rate in skeletal muscle for several hours after completing a bout of exercise. We studied the effect of exercise on the glucose transport activity of isolated epitrochlearis muscles from male Fischer 344/Brown Norway F1 hybrid rats across a wide range of the life-span (at 3.5, 13, and 25 mo). The stimulation of 3-O-methylglucose (3-MG) accumulation by a submaximally effective insulin concentration (100 microU/ml) was enhanced (50–75%) 4 h after exercise, regardless of age. In contrast, the 3-MG transport rate with 20,000 microU/ml insulin was enhanced after exercise only in the youngest rats (35%), and this increased responsiveness occurred despite no changes in muscle total GLUT-4 levels. In addition, epitrochlearis GLUT-4 levels were reduced by 29% between 3.5 and 13 mo of age in sedentary rats but did not decline further between 13 and 25 mo of age. GLUT-4 levels were moderately but significantly (P < 0.05) related (r = 0.554) to epitrochlearis muscle capacity for insulin-stimulated 3-MG transport.

Assessment of the Contractile Properties of Permeabilized Skeletal Muscle Fibers

2016 ◽  
pp. 321-336 ◽  
Author(s):  
Dennis R. Claflin ◽  
Stuart M. Roche ◽  
Jonathan P. Gumucio ◽  
Christopher L. Mendias ◽  
Susan V. Brooks
Keyword(s):  
Skeletal Muscle ◽  
Muscle Fibers ◽  
Contractile Properties ◽  
Skeletal Muscle Fibers
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