scholarly journals Wheal and flare reactions in skin prick tests of patients treated with montelukast alone or in combination with antihistamines

2013 ◽  
Vol 63 (3) ◽  
pp. 191-195 ◽  
Author(s):  
Malgorzata Gorska Ciebiada ◽  
Marcin Barylski ◽  
Maciej Ciebiada
Author(s):  
Gerald W. Volcheck

Standard allergy testing relies on identifying the immunoglobulin (Ig) E antibody specific for the allergen in question. Two classic methods of doing this are the immediate wheal-and-flare skin prick tests (in which a small amount of antigen is introduced into the skin and the site is evaluated after 15 minutes for the presence of an immediate wheal-and-flare reaction) and in vitro (blood) testing. Methods of allergy testing that do not have a clear scientific basis include cytotoxic testing, provocation-neutralization testing or treatment, and “yeast allergy” testing.


Author(s):  
Gerald W. Volcheck

Standard allergy testing relies on identifying the IgE antibody specific for the allergen in question. Two classic methods of doing this are the immediate wheal-and-flare skin prick tests (a small amount of antigen is introduced into the skin and evaluated at 15 minutes for the presence of an immediate wheal-and-flare reaction) and in vitro testing. Allergy testing that does not have a clear scientific basis includes cytotoxic testing, provocation-neutralization testing or treatment, and "yeast allergy" testing. Allergy-related conditions such as asthma, chronic rhinitis, urticaria and angioedema, anaphylaxis, food allergy, stinging insect allergy, and drug allergy are reviewed.


2016 ◽  
Vol 10 (02) ◽  
pp. 88-92
Author(s):  
M. Gramß ◽  
A. Hiemisch ◽  
W. Kiess

ZusammenfassungIn den letzten beiden Jahrzehnten stiegen die Prävalenzen von Asthma bronchiale und Übergewicht parallel an. Für beide Erkrankungen werden ähnliche Ursachen diskutiert: umweltbezogene, genetische, sozioökonomische Faktoren und sogar die Einflussnahme durch Adipokine. Außerdem rückte das Übergewicht als potenzieller Auslöser und begünstigender Faktor von Asthma bronchiale in den Fokus der Forschung. Der BMI ist sowohl mit der Diagnose Asthma als auch mit dem Symptom „wheezing” positiv korreliert. Übergewichtige Kinder weisen größere IgESpiegel und häufiger Atopien auf. Jedoch zeigen Kinder mit größerem BMI häufiger nichtatopisches als atopisches Asthma bronchiale. Zudem sind allergische Tests wie bronchiale Hyperreagibilität und Skin Prick Tests bei adipösen Kindern nicht häufiger positiv als bei normalgewichtigen Kindern. Die Lungenfunktionswerte bei Übergewicht werden häufig als Minderung des Tiffeneau-Index (FEV1/FVK) beschrieben. Allerdings ist auch hier der Zusammenhang noch unklar, vor allem die Reaktion adipöser Kinder auf medikamentöse Broncholyse als Bestandteil der Spirometrie-Testung. Die nicht durchgängig einheitlichen und teilweise nicht signifikanten Studienergebnisse lassen daher nicht auf eine unmittelbare Verbindung von Asthma und Adipositas oder auf den Einfluss von Kovariablen auf deren Verhältnis schließen. Die LIFE Child-Kohorte soll zur Klärung offener Fragen beitragen.


Author(s):  
Esen Demir ◽  
Levent Midyat ◽  
Figen Gulen ◽  
Gulhadiye Akbas ◽  
Sema Tanrıverdi ◽  
...  

Children ◽  
2021 ◽  
Vol 8 (6) ◽  
pp. 497
Author(s):  
Aikaterini Anagnostou

Background: Food allergies are common, affecting 1 in 13 school children in the United States and their prevalence is increasing. Many misconceptions exist with regards to food allergy prevention, diagnosis and management. Objective: The main objective of this review is to address misconceptions with regards to food allergies and discuss the optimal, evidence-based approach for patients who carry this diagnosis. Observations: Common misconceptions in terms of food allergy prevention include beliefs that breastfeeding and delayed introduction of allergenic foods prevent the development of food allergies. In terms of diagnosis, statements such as ‘larger skin prick tests or/and higher levels of food-specific IgE can predict the severity of food-induced allergic reactions’, or ‘Tryptase is always elevated in food-induced anaphylaxis’ are inaccurate. Additionally, egg allergy is not a contraindication for receiving the influenza vaccine, food-allergy related fatalities are rare and peanut oral immunotherapy, despite reported benefits, is not a cure for food allergies. Finally, not all infants with eczema will develop food allergies and epinephrine auto-injectors may unfortunately be both unavailable and underused in food-triggered anaphylaxis. Conclusions and relevance: Healthcare professionals must be familiar with recent evidence in the food allergy field and avoid common misunderstandings that may negatively affect prevention, diagnosis and management of this chronic disease.


2021 ◽  
Vol 147 (2) ◽  
pp. AB171
Author(s):  
Pasquale Mulé ◽  
Bruce Mazer ◽  
Danbing Ke ◽  
Duncan Lejtenyi ◽  
Liane Beaudette ◽  
...  

Allergy ◽  
1994 ◽  
Vol 49 (9) ◽  
pp. 702-706 ◽  
Author(s):  
M. Christensen ◽  
L. Moelby ◽  
F. Svendsen
Keyword(s):  

Allergy ◽  
2000 ◽  
Vol 55 (4) ◽  
pp. 382-385 ◽  
Author(s):  
R. Fadel ◽  
I. Ramboer ◽  
N. Chatterjee ◽  
J.-P. Rihoux ◽  
M.-P. Derde

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