Simultaneous determination of sparfloxacin and commonly used H2 receptor antagonists by RP-HPLC: application to in vitro drug interactions

2011 ◽  
Vol 21 (7) ◽  
pp. 974-982 ◽  
Author(s):  
Najma Sultana ◽  
M. Saeed Arayne ◽  
Somia Gul ◽  
Mahwish Akhtar ◽  
Sana Shamim
Keyword(s):  
Drug Interactions ◽  
Simultaneous Determination ◽  
Receptor Antagonists ◽  
H2 Receptor Antagonists ◽  
H2 Receptor ◽  
Rp Hplc

A sensitive HPLC-FL method to simultaneously determine febuxostat and diclofenac in rat plasma: assessment of metabolic drug interactions in vitro and in vivo

2020 ◽  
Vol 12 (16) ◽  
pp. 2166-2175 ◽  
Author(s):  
Dong-Gyun Han ◽  
Kyu-Sang Kim ◽  
Seong-Wook Seo ◽  
Young Mee Baek ◽  
Yunjin Jung ◽  
...  
Keyword(s):  
Sample Preparation ◽  
Drug Interactions ◽  
Simultaneous Determination ◽  
Small Volume ◽  
Rat Plasma ◽  
Metabolic Drug ◽  
Simple Sample Preparation

We developed a sensitive, simple and validated HPLC-FL method for simultaneous determination of FEB and DIC in rat plasma. The method requires a relatively small volume of sample, has simple sample preparation and excellent sensitivity.

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