APOA5 gene variation modulates the effects of dietary fat intake on body mass index and obesity risk in the Framingham Heart Study

2007 ◽  
Vol 85 (2) ◽  
pp. 119-128 ◽  
Author(s):  
Dolores Corella ◽  
Chao-Qiang Lai ◽  
Serkalem Demissie ◽  
L. Adrienne Cupples ◽  
Alisa K. Manning ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Dietary Fat ◽  
Framingham Heart Study ◽  
Fat Intake ◽  
Obesity Risk ◽  
Gene Variation ◽  
Dietary Fat Intake ◽  
Heart Study ◽  
Apoa5 Gene

PPARγ Pro12Ala Polymorphism Influences the Relationship between Dietary Fat Intake, Adiposity and Lipid Profile in Patients with Type 2 Diabetes

2018 ◽  
Vol 88 (5-6) ◽  
pp. 263-269 ◽  
Author(s):  
Fariba Koohdani ◽  
Gity Sotoudeh ◽  
Zahra Kalantar ◽  
Anahita Mansoori
Keyword(s):  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Body Mass ◽  
Dietary Fat ◽  
Fat Intake ◽  
Pro12ala Polymorphism ◽  
Dietary Fat Intake ◽  
Metabolic Syndrome Components

Abstract. Background: Peroxisome proliferator-activated receptor γ (PPARγ) Pro12Ala polymorphism (rs1801282) has been associated with metabolic syndrome components in some studies. Moreover, the PPARγ gene may mediate the physiological response to dietary fat intake in a ligand-dependent manner. Methods: Metabolic syndrome components (body mass index, waist circumference, and lipid profile) were determined in 290 type 2 diabetes mellitus patients in a cross-sectional study. DNA genotyping for determining PPARγ Pro12Ala polymorphism was conducted using the polymerase chain reaction-restriction length polymorphism method. A semi-quantitative food frequency questionnaire was used to assess the participants’ dietary intakes in the previous year. Results: There were significant differences between the two genotype groups of PPARγ Pro12Ala polymorphism, Ala carriers (Pro/Ala + Ala/Ala) versus non-Ala carriers (Pro/Pro), in terms of mean body mass index (p = 0.04) and waist circumference (p = 0.02). Below the median percentage of energy from monounsaturated and polyunsaturated fatty acids, Ala carriers had a higher body mass index (p = 0.01) compared to non-Ala carriers. Furthermore, a significant interaction between this single-nucleotide polymorphism and polyunsaturated fatty acids intake on serum triglyceride levels (p = 0.01) was seen, and in higher polyunsaturated fatty acids intake (≥ median) Ala carriers had lower triglyceride levels than non-Ala carriers (p = 0.007). Conclusions: The findings of the current study support a significant association between PPARγ Pro12Ala polymorphism and metabolic syndrome components, and they suggest that this polymorphism can modulate the biological response of dietary fat intake on body mass index and triglyceride levels.

scholarly journals APOA5 Gene Variation Interacts with Dietary Fat Intake to Modulate Obesity and Circulating Triglycerides in a Mediterranean Population

2011 ◽  
Vol 141 (3) ◽  
pp. 380-385 ◽  
Author(s):  
Carmen Sánchez-Moreno ◽  
Jose M. Ordovás ◽  
Caren E. Smith ◽  
Juan C. Baraza ◽  
Yu-Chi Lee ◽  
...  
Keyword(s):  
Dietary Fat ◽  
Mediterranean Population ◽  
Fat Intake ◽  
Gene Variation ◽  
Dietary Fat Intake ◽  
Apoa5 Gene

scholarly journals Dietary fat intake and body mass index in Spanish children

2000 ◽  
Vol 72 (5) ◽  
pp. 1399s-1403s ◽  
Author(s):  
Luis A Moreno ◽  
Antonio Sarría ◽  
Aurora Lázaro ◽  
Manuel Bueno
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Dietary Fat ◽  
Fat Intake ◽  
Dietary Fat Intake

Advertising’s Relationship to Public Housing Residents’ Body Mass Index (BMI) and Dietary Fat Intake

2006 ◽  
Vol 106 (8) ◽  
pp. A61
Author(s):  
K.M. Booth ◽  
R.E. Lee ◽  
G.R. Regan ◽  
J.Y. Reese-Smith ◽  
H.H. Howard ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Public Housing ◽  
Body Mass ◽  
Dietary Fat ◽  
Fat Intake ◽  
Dietary Fat Intake ◽  
Public Housing Residents

Atherogenic lipid profiles in Filipino adolescents with low body mass index and low dietary fat intake

2003 ◽  
Vol 15 (5) ◽  
pp. 688-696 ◽  
Author(s):  
Christopher W. Kuzawa ◽  
Linda S. Adair ◽  
Joesphine L. Avila ◽  
Joseph H.C. Cadungog ◽  
Ngoc-anh Le
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Dietary Fat ◽  
Lipid Profiles ◽  
Fat Intake ◽  
Dietary Fat Intake ◽  
Low Body Mass Index ◽  
Atherogenic Lipid

scholarly journals Relation of Platelet and Leukocyte Inflammatory Transcripts to Body Mass Index in the Framingham Heart Study

Circulation ◽  
2010 ◽  
Vol 122 (2) ◽  
pp. 119-129 ◽  
Author(s):  
Jane E. Freedman ◽  
Martin G. Larson ◽  
Kahraman Tanriverdi ◽  
Christopher J. O'Donnell ◽  
Kristine Morin ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Framingham Heart Study ◽  
Heart Study

scholarly journals Metabolomic Profiles of Body Mass Index in the Framingham Heart Study Reveal Distinct Cardiometabolic Phenotypes

PLoS ONE ◽  
2016 ◽  
Vol 11 (2) ◽  
pp. e0148361 ◽  
Author(s):  
Jennifer E. Ho ◽  
Martin G. Larson ◽  
Anahita Ghorbani ◽  
Susan Cheng ◽  
Ming-Huei Chen ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Framingham Heart Study ◽  
Heart Study

Nutritional education program: Dietary fat intake and LDL-C modification in the brisighella heart study (BHS)

1999 ◽  
Vol 144 ◽  
pp. 140
Author(s):  
A.F.G. Cicero ◽  
S. D'Addato ◽  
A. Dormi ◽  
M.C. Grippo ◽  
Z. Sangiorgi ◽  
...  
Keyword(s):  
Education Program ◽  
Dietary Fat ◽  
Fat Intake ◽  
Nutritional Education ◽  
Dietary Fat Intake ◽  
Heart Study

scholarly journals Dietary fat intake and risk of coronary heart disease: the Strong Heart Study

2006 ◽  
Vol 84 (4) ◽  
pp. 894-902 ◽  
Author(s):  
Jiaqiong Xu ◽  
Sigal Eilat-Adar ◽  
Catherine Loria ◽  
Uri Goldbourt ◽  
Barbara V Howard ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Dietary Fat ◽  
Fat Intake ◽  
Strong Heart Study ◽  
Dietary Fat Intake ◽  
Heart Study

scholarly journals Proximity to Food Establishments and Body Mass Index in the Framingham Heart Study Offspring Cohort Over 30 Years

2011 ◽  
Vol 174 (10) ◽  
pp. 1108-1114 ◽  
Author(s):  
Jason P. Block ◽  
Nicholas A. Christakis ◽  
A. James O’Malley ◽  
S. V. Subramanian
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Framingham Heart Study ◽  
Offspring Cohort ◽  
Heart Study
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