Internal tibial rotation during in vivo, dynamic activity induces greater sliding of tibio-femoral joint contact on the medial compartment

2011 ◽  
Vol 20 (7) ◽  
pp. 1268-1275 ◽  
Author(s):  
Yuichi Hoshino ◽  
Scott Tashman
Keyword(s):  
Medial Compartment ◽  
Tibial Rotation ◽  
Dynamic Activity ◽  
Joint Contact ◽  
Internal Tibial Rotation

scholarly journals Posterior Tibial Subchondral Bone and Meniscal Slope Correlate with In Vivo Internal Tibial Rotation

2017 ◽  
Vol 5 (7_suppl6) ◽  
pp. 2325967117S0030
Author(s):  
Elmar Herbst ◽  
Tom Gale ◽  
Kanto Nagai ◽  
Yasutaka Tashiro ◽  
James J. Irrgang ◽  
...  
Keyword(s):  
Subchondral Bone ◽  
Tibial Rotation ◽  
Posterior Tibial ◽  
Internal Tibial Rotation

scholarly journals The difference between the medial and lateral posterior tibial slope is associated with greater internal tibial rotation

2018 ◽  
Vol 6 (4_suppl2) ◽  
pp. 2325967118S0003
Author(s):  
Elmar Herbst ◽  
Andreas Imhoff ◽  
James Irrgang ◽  
William Anderst ◽  
Freddie Fu
Keyword(s):  
Acl Reconstruction ◽  
Tibial Slope ◽  
Tibial Rotation ◽  
Tibial Shaft ◽  
Posterior Tibial ◽  
Downhill Running ◽  
Lateral Posterior ◽  
Internal Tibial Rotation ◽  
The Difference

The objective of this study was to investigate the effect of lateral and medial posterior tibial slope (PTS) and meniscal slope (PMS) on in-vivo anterior tibial translation (ATT) and internal tibial rotation (IR) during downhill running on the healthy contralateral knee twenty-four months after ACL reconstruction. Forty-two individuals (twenty-six males; mean age 21.2 ± 6.9 years) who underwent unilateral ACL reconstruction were included in this study. Morphologic parameters were measured on 3 T magnetic resonance images (MRI) using the 3D DESS sequence on the ACL reconstructed and healthy contralateral knee. Lateral and medial PTS and PMS were measured according to the method described by Hudek et al. Briefly, the tibial shaft axis was determined by connecting the centroids of two circles fitting the tibial shaft on the central sagittal MRI slice. The PTS and PMS were determined by the angle between the tibial shaft axis and the line connecting the two most proximal anterior and posterior subchondral bone and meniscal points in the center of each joint compartment. Three-dimensional in-vivo kinematics data were acquired using dynamic stereo x-ray during downhill running (3.0 m/s, 10° slope) at 150 Hz twenty-four months after unilateral ACL reconstruction. A multiple regression analysis was performed (p < .05). The lateral and medial PTS and PMS as well as the differences between the medial and lateral compartment slopes were not significantly related to ATT in the healthy contralateral knees twenty-four months after ACL reconstruction (p > .05). The lateral and medial PTS and PMS were not significantly related to peak internal tibial rotation (p > .05). However, the difference between the medial and lateral PTS as well as PMS was associated with greater internal tibial rotation (PTS: b=1.55, p < .001; PMS: b = .71, p = .02). The most important finding of the present study is that the difference between the medial and lateral posterior tibial and meniscal slope are related to in-vivo internal tibial rotation during downhill running. ATT was not significantly influenced by the tibial bony and meniscal morphology. Taking into account the results of the present study, the difference between the medial and the lateral PTS and PMS may contribute to IR when an ACL injury occurs. However, the analyzed movement was a straight-ahead run without any cutting or pivoting maneuvers commonly related to ACL tears. In such motion patterns, the correlations may be even stronger compared to the results of this study.

scholarly journals More passive internal tibial rotation with posterior cruciate ligament retention than with excision in a medial pivot TKA implanted with unrestricted caliper verified kinematic alignment

2021 ◽  
Author(s):  
Alexander J. Nedopil ◽  
Stephen M. Howell ◽  
Maury L. Hull
Keyword(s):  
Posterior Cruciate Ligament ◽  
Cruciate Ligament ◽  
Kinematic Alignment ◽  
Tibial Rotation ◽  
Medial Condyle ◽  
Mean Values ◽  
Medial Pivot ◽  
Internal Tibial Rotation ◽  
Lift Off

Abstract Purpose Excision of the posterior cruciate ligament (PCL) is recommended when implanting a medial pivot (MP) total knee arthroplasty (TKA) to reduce the risk of limiting flexion by over-tensioning the flexion space. The present study determined whether PCL retention (1) limits internal tibial rotation and (2) causes anterior lift-off of the insert in 90° flexion after implantation of an MP design with unrestricted caliper verified kinematic alignment (KA). Methods Four surgeons implanted an MP TKA design with medial ball-in-socket and lateral flat tibial insert in ten fresh-frozen cadaveric knees. Before and after PCL excision, trial inserts with medial goniometric markings measured the angular I–E tibial orientation relative to the trial femoral component's medial condyle in extension and at 90° flexion, and the surgeon recorded the occurrence of anterior lift-off of the insert at 90° flexion. Results PCL retention resulted in greater internal tibial rotation than PCL excision, with mean values of 15° vs 7° degrees from maximum extension to 90° flexion, respectively (p < 0.0007). At 90° flexion, no TKAs with PCL retention and one TKA with PCL excision had anterior lift-off of the insert (N.S.). Conclusions This preliminary study of ten cadaveric knees showed that PCL retention restored more passive internal tibial rotation than PCL excision with a negligible risk of anterior lift-off. However, in vivo analysis from multiple authors with a larger sample size is required to recommend PCL retention with an MP TKA design implanted with unrestricted caliper verified KA.

A New Device for Measuring Knee Rotational Kinematics Using Magnetic Resonance Imaging

2008 ◽  
Vol 2 (4) ◽  
Author(s):  
R. Dana Carpenter ◽  
Sandra J. Shefelbine ◽  
Jesus Lozano ◽  
Julio Carballido-Gamio ◽  
Sharmila Majumdar ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Recovery Of Function ◽  
Rotational Stability ◽  
Tibial Rotation ◽  
Resonance Imaging ◽  
New Device ◽  
Internal Tibial Rotation ◽  
Acl Deficient

There are few commonly used clinical techniques to quantify the rotational stability and joint contact kinematics in knees in vivo. A magnetic-resonance-imaging-compatible device capable of applying axial and torsional loads to the foot was developed and used to measure in vivo knee kinematics in 14 healthy volunteers. The device was used to apply an internal torque and an axial compressive load at the foot, with the thigh held in place. Sagittal scans were made of the knee with and without an applied internal torque, and three-dimensional geometric representations of the knee joint were constructed from the images. Repeat scans of four volunteers were performed to assess precision, and phantom scans were performed to assess accuracy. Rotational measurements had a root mean square error of 0.1 deg, and precision errors for repeat measurements were 1.6 deg for internal tibial rotation, 0.3–1.1 mm for contact centroid translations, and 24.5 mm2 for a contact area. Results indicated that the device induced significant internal tibial rotation with respect to the femur and significant translation of the medial and lateral contact centroids. A preliminary study on five anterior cruciate ligament (ACL)-deficient patients did not detect any rotational difference between ACL-deficient and contralateral knees under an isolated internal torque. This method is able to calculate rotations and centroid translations out of the scan plane and has potential applications in investigating the effects of knee injury and recovery of function.

scholarly journals Evaluating Retinal and Choroidal Perfusion Changes after Isometric and Dynamic Activity Using Optical Coherence Tomography Angiography

Diagnostics ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 808
Author(s):  
Max Philipp Brinkmann ◽  
Nikolas Xavier Kibele ◽  
Michelle Prasuhn ◽  
Vinodh Kakkassery ◽  
Mario Damiano Toro ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Isometric Exercise ◽  
Dynamic Exercise ◽  
Exercise Heart Rate ◽  
Optical Coherence ◽  
Dynamic Activity ◽  
Capillary Plexus ◽  
Choroidal Perfusion

Optical coherence tomography angiography (OCTA) is a non-invasive tool for imaging and quantifying the retinal and choroidal perfusion state in vivo. This study aimed to evaluate the acute effects of isometric and dynamic exercise on retinal and choroidal sublayer perfusion using OCTA. A pilot study was conducted on young, healthy participants, each of whom performed a specific isometric exercise on the first day and a dynamic exercise the day after. At baseline and immediately after the exercise, heart rate (HR), mean arterial pressure (MAP), superficial capillary plexus perfusion (SCPP), deep capillary plexus perfusion (DCPP), choriocapillaris perfusion (CCP), Sattlers’s layer perfusion (SLP), and Haller’s layer perfusion (HLP) were recorded. A total of 34 eyes of 34 subjects with a mean age of 32.35 ± 7.87 years were included. HR as well as MAP increased significantly after both types of exercise. Both SCPP and DCPP did not show any significant alteration due to isometric or dynamic exercise. After performing dynamic exercise, CCP, SLP, as well as HLP significantly increased. Changes in MAP correlated significantly with changes in HLP after the dynamic activity. OCTA-based analysis in healthy adults following physical activity demonstrated a constant retinal perfusion, supporting the theory of autoregulatory mechanisms. Dynamic exercise, as opposed to isometric activity, significantly changed choroidal perfusion. OCTA imaging may represent a novel and sensitive tool to expand the diagnostic spectrum in the field of sports medicine.

scholarly journals Towards planning of osteotomy around the knee with quantitative inclusion of the adduction moment: a biomechanical approach

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Margit Biehl ◽  
Philipp Damm ◽  
Adam Trepczynski ◽  
Stefan Preiss ◽  
Gian Max Salzmann
Keyword(s):  
Gait Analysis ◽  
Measurement Data ◽  
Frontal Plane ◽  
Medial Compartment ◽  
Knee Adduction Moment ◽  
In Vivo Measurement ◽  
Force Ratio ◽  
Leg Alignment ◽  
Alignment Angle

Abstract Purpose Despite practised for decades, the planning of osteotomy around the knee, commonly using the Mikulicz-Line, is only empirically based, clinical outcome inconsistent and the target angle still controversial. A better target than the angle of frontal-plane static leg alignment might be the external frontal-plane lever arm (EFL) of the knee adduction moment. Hypothetically assessable from frontal-plane-radiograph skeleton dimensions, it might depend on the leg-alignment angle, the hip-centre-to-hip-centre distance, the femur- and tibia-length. Methods The target EFL to achieve a medial compartment force ratio of 50% during level-walking was identified by relating in-vivo-measurement data of knee-internal loads from nine subjects with instrumented prostheses to the same subjects’ EFLs computed from frontal-plane skeleton dimensions. Adduction moments derived from these calculated EFLs were compared to the subjects’ adduction moments measured during gait analysis. Results Highly significant relationships (0.88 ≤ R2 ≤ 0.90) were found for both the peak adduction moment measured during gait analysis and the medial compartment force ratio measured in vivo to EFL calculated from frontal-plane skeleton dimensions. Both correlations exceed the respective correlations with the leg alignment angle, EFL even predicts the adduction moment’s first peak. The guideline EFL for planning osteotomy was identified to 0.349 times the epicondyle distance, hence deducing formulas for individualized target angles and Mikulicz-Line positions based on full-leg radiograph skeleton dimensions. Applied to realistic skeleton geometries, widespread results explain the inconsistency regarding correction recommendations, whereas results for average geometries exactly meet the most-consented “Fujisawa-Point”. Conclusion Osteotomy outcome might be improved by planning re-alignment based on the provided formulas exploiting full-leg-radiograph skeleton dimensions.

scholarly journals Circuit-dependent striatal PKA and ERK signaling underlies rapid behavioral shift in mating reaction of male mice

2015 ◽  
Vol 112 (21) ◽  
pp. 6718-6723 ◽  
Author(s):  
Akihiro Goto ◽  
Ichiro Nakahara ◽  
Takashi Yamaguchi ◽  
Yuji Kamioka ◽  
Kenta Sumiyama ◽  
...  
Keyword(s):  
D2 Receptor ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Signaling Cascades ◽  
Male Mice ◽  
Indirect Pathway ◽  
Dynamic Activity ◽  
Reward Seeking ◽  
Electric Shocks

The selection of reward-seeking and aversive behaviors is controlled by two distinct D1 and D2 receptor-expressing striatal medium spiny neurons, namely the direct pathway MSNs (dMSNs) and the indirect pathway MSNs (iMSNs), but the dynamic modulation of signaling cascades of dMSNs and iMSNs in behaving animals remains largely elusive. We developed an in vivo methodology to monitor Förster resonance energy transfer (FRET) of the activities of PKA and ERK in either dMSNs or iMSNs by microendoscopy in freely moving mice. PKA and ERK were coordinately but oppositely regulated between dMSNs and iMSNs by rewarding cocaine administration and aversive electric shocks. Notably, the activities of PKA and ERK rapidly shifted when male mice became active or indifferent toward female mice during mating behavior. Importantly, manipulation of PKA cascades by the Designer Receptor recapitulated active and indifferent mating behaviors, indicating a causal linkage of a dynamic activity shift of PKA and ERK between dMSNs and iMSNs in action selection.

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