Comparison of hip fracture and osteoporosis medication prescription rates across Canadian provinces

Background/Objectives:The course of multiple sclerosis may be slowed by use of the disease modifying drugs (DMDs): subcutaneous or intramuscular interferon beta-1a, interferon beta-1b, glatiramer acetate, and natalizumab. We set out to compare utilization of these drugs in the Canadian provinces from 2002-2007.Methods:Using a retrospective cohort analysis, we reviewed population data from International Medical Statistics (IMS) Health between November 2001 and October 2007.Results:The total annual number of DMD prescriptions increased from 3.9, in 2002, to 5.1, in 2007, per 1,000 Canadians. The total annual cost of prescriptions rose from $187 million to $287 million. Of the four provinces responsible for the majority of prescriptions - Alberta, BC, Ontario, and Quebec - Quebec had the highest average annual prescription rate (7 per 1,000 population) and BC had the lowest rate (3.3 per 1,000 population). Subcutaneous interferon beta-1a was the most commonly used drug whereas glatiramer acetate showed the greatest growth in use from 2002 to 2007.Conclusions:Disease modifying drugs prescription rates and costs increased by more than 30% between 2002 and 2007. There was wide variation in DMD prescription rates and relative drug preferences across the provinces.

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Access to Anti-osteoporosis Medication after Hip Fracture in Korean Elderly Patients

Maturitas ◽

10.1016/j.maturitas.2017.06.021 ◽

2017 ◽

Vol 103 ◽

pp. 54-59 ◽

Cited By ~ 8

Author(s):

Yun Mi Yu ◽

Ju-Yeun Lee ◽

Euni Lee

Keyword(s):

Hip Fracture ◽

Elderly Patients ◽

Osteoporosis Medication ◽

Korean Elderly

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Osteoporosis Medication Use After Hip Fracture in U.S. Patients Between 2002 and 2011

Journal of Bone and Mineral Research ◽

10.1002/jbmr.2202 ◽

2014 ◽

Vol 29 (9) ◽

pp. 1929-1937 ◽

Cited By ~ 175

Author(s):

Daniel H Solomon ◽

Stephen S Johnston ◽

Natalie N Boytsov ◽

Donna McMorrow ◽

Joseph M Lane ◽

...

Keyword(s):

Hip Fracture ◽

Medication Use ◽

Osteoporosis Medication

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Improving Discharge Medication Prescription Rates for ACS Patients at Tauranga Hospital, a Quality Improvement Initiative- ANZACS-QI

Heart Lung and Circulation ◽

10.1016/j.hlc.2016.05.018 ◽

2016 ◽

Vol 25 ◽

pp. S7

Author(s):

Chethan Kasargod ◽

Jennifer Goodson ◽

Jonathan Tisch

Keyword(s):

Quality Improvement ◽

Quality Improvement Initiative ◽

Medication Prescription ◽

Discharge Medication ◽

Prescription Rates

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Operationalising a conceptual framework for a contiguous hospitalisation episode to study associations between surgical timing and death after first hip fracture: a Canadian observational study

BMJ Open ◽

10.1136/bmjopen-2017-020372 ◽

2018 ◽

Vol 8 (12) ◽

pp. e020372

Author(s):

Katie Jane Sheehan ◽

Adrian R Levy ◽

Boris Sobolev ◽

Pierre Guy ◽

Michael Tang ◽

...

Keyword(s):

Hip Fracture ◽

Observational Study ◽

Conceptual Framework ◽

Acute Care ◽

Acute Care Hospital ◽

Secondary Outcome ◽

Care Hospital ◽

Surgical Timing ◽

Episodes Of Care ◽

Canadian Provinces

ObjectiveWe describe steps to operationalise a published conceptual framework for a contiguous hospitalisation episode using acute care hospital discharge abstracts. We then quantified the degree of bias induced by a first abstract episode, which does not account for hospital transfers.DesignRetrospective observational study.SettingAll acute care hospitals in nine Canadian provinces.ParticipantsWe retrieved acute hospitalisation discharge abstracts for 189 448 patients aged 65 years and older admitted to acute care with hip fracture between 2003 and 2013.Primary and secondary outcome measuresThe percentage of patients treated surgically, delayed to surgery (defined as two or more days after admission) and dying, between contiguous hospitalisation episodes and the first abstract episodes of care.ResultsUsing contiguous hospitalisation episodes, 91.6% underwent surgery, 35.7% were delayed two or more days after admission and 6.7% died postoperatively, whereas, using the first abstract only, these percentages were 83.7%, 32.5% and 6.5%, respectively.ConclusionWe demonstrate that not accounting for hospital transfers when evaluating the association between surgical timing and death underestimates reporting of the percentage of patients treated surgically and delayed to surgery by 9%, and the percentage who die after surgery by 3%. Researchers must be aware of this potential and avoidable bias as, depending on the purpose of the study, erroneous inferences may be drawn.

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Problems managed and medications prescribed during encounters with people with autism spectrum disorder in Australian general practice

Autism ◽

10.1177/1362361317714588 ◽

2017 ◽

Vol 22 (8) ◽

pp. 995-1004 ◽

Cited By ~ 3

Author(s):

Rachael C Birch ◽

Kitty-Rose Foley ◽

Allan Pollack ◽

Helena Britt ◽

Nicholas Lennox ◽

...

Keyword(s):

Autism Spectrum Disorder ◽

Healthcare Providers ◽

The United States ◽

Autism Spectrum ◽

Spectrum Disorder ◽

Physical And Mental Health ◽

Prescribing Practices ◽

Medication Prescription ◽

Prescription Rates ◽

Health Programme

Autism spectrum disorder is associated with high rates of co-occurring health conditions. While elevated prescription rates of psychotropic medications have been reported in the United Kingdom and the United States, there is a paucity of research investigating clinical and prescribing practices in Australia. This study describes the problems managed and medications prescribed by general practitioners in Australia during encounters where an autism spectrum disorder was recorded. Information was collected from 2000 to 2014 as part of the Bettering the Evaluation and Care of Health programme. Encounters where patients were aged less than 25 years and autism spectrum disorder was recorded as one of the reasons for encounter and/or problems managed ( n = 579) were compared to all other Bettering the Evaluation and Care of Health programme encounters with patients aged less than 25 years ( n = 281,473). At ‘autism spectrum disorder’ encounters, there was a significantly higher management rate of psychological problems, and significantly lower management rates of skin, respiratory and general/unspecified problems, than at ‘non-autism spectrum disorder’ encounters. The rate of psychological medication prescription was significantly higher at ‘autism spectrum disorder’ encounters than at ‘non-autism spectrum disorder’ encounters. The most common medications prescribed at ‘autism spectrum disorder’ encounters were antipsychotics and antidepressants. Primary healthcare providers need adequate support and training to identify and manage physical and mental health concerns among individuals with autism spectrum disorder.

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