The novel vasopressin receptor (V1aR) antagonist SRX246 reduces anxiety in an experimental model in humans: a randomized proof-of-concept study

Psychopharmacology ◽

10.1007/s00213-021-05861-4 ◽

2021 ◽

Author(s):

Tiffany R. Lago ◽

Michael J. Brownstein ◽

Emily Page ◽

Emily Beydler ◽

Adrienne Manbeck ◽

...

Keyword(s):

Experimental Model ◽

Vasopressin Receptor ◽

The Novel ◽

Proof Of Concept ◽

Download Full-text

Assessment of the novel T-cell activation marker–tuberculosis assay for diagnosis of active tuberculosis in children: a prospective proof-of-concept study

The Lancet Infectious Diseases ◽

10.1016/s1473-3099(14)70884-9 ◽

2014 ◽

Vol 14 (10) ◽

pp. 931-938 ◽

Author(s):

Damien Portevin ◽

Felicien Moukambi ◽

Petra Clowes ◽

Asli Bauer ◽

Mkunde Chachage ◽

...

Keyword(s):

T Cell ◽

T Cell Activation ◽

Cell Activation ◽

Active Tuberculosis ◽

The Novel ◽

Proof Of Concept ◽

Concept Study ◽

Activation Marker ◽

Cell Activation Marker ◽

Tuberculosis In Children

Download Full-text

Faculty Opinions recommendation of Targeted adsorption of molecules in the colon with the novel adsorbent-based medicinal product, DAV132: A proof of concept study in healthy subjects.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725971801.793526577 ◽

2016 ◽

Author(s):

José Luis Martínez

Keyword(s):

Medicinal Product ◽

Healthy Subjects ◽

The Novel ◽

Proof Of Concept ◽

Download Full-text

A novel approach of using brachial plexus blockade as an experimental model for diagnosis of intraoperative nerve dysfunction with somatosensory evoked potentials: a blinded proof-of-concept study

Canadian Journal of Anesthesia/Journal canadien d anesthésie ◽

10.1007/s12630-021-01975-7 ◽

2021 ◽

Author(s):

Jason Chui ◽

Alex Freytag ◽

Greydon Glimore ◽

Shalini Dhir ◽

Max Rachinsky ◽

...

Keyword(s):

Evoked Potentials ◽

Brachial Plexus ◽

Experimental Model ◽

Somatosensory Evoked Potentials ◽

Proof Of Concept ◽

Concept Study ◽

Novel Approach ◽

Brachial Plexus Blockade ◽

Nerve Dysfunction

Download Full-text

Targeted adsorption of molecules in the colon with the novel adsorbent-based Medicinal Product, DAV132: A proof of concept study in healthy subjects

The Journal of Clinical Pharmacology ◽

10.1002/jcph.359 ◽

2014 ◽

Vol 55 (1) ◽

pp. 10-16 ◽

Author(s):

Jean de Gunzburg ◽

Annie Ducher ◽

Christiane Modess ◽

Danilo Wegner ◽

Stefan Oswald ◽

...

Keyword(s):

Medicinal Product ◽

Healthy Subjects ◽

The Novel ◽

Proof Of Concept ◽

Download Full-text

A Cadaveric Model for Measuring Continuous Positive Airway Pressure (CPAP) in the Nasal Cavity and Paranasal Sinuses: A Proof of Concept Study

10.1055/s-0039-1679476 ◽

2019 ◽

Author(s):

Ryan Rimmer ◽

Chandala Chitguppi ◽

Hermes Garcia ◽

Ian Koszewski ◽

Gurston Nyquist ◽

...

Keyword(s):

Continuous Positive Airway Pressure ◽

Nasal Cavity ◽

Paranasal Sinuses ◽

Airway Pressure ◽

Positive Airway Pressure ◽

Proof Of Concept ◽

Concept Study ◽

Cadaveric Model

Download Full-text

HABITUATION AS PARAMETER FOR PREDICTION OF MENTAL DEVELOPMENT IN HEALTHY PRETERM INFANTS: AN EEG PROOF-OF-CONCEPT STUDY

10.26226/morressier.57d034d0d462b802923830ad ◽

2016 ◽

Author(s):

Antoinette DEPOORTER

Keyword(s):

Preterm Infants ◽

Mental Development ◽

Proof Of Concept ◽

Download Full-text

Treatment of Female Genital Schistosomiasis (FGS) With Praziquantel: A Proof-of-Concept Study

Case Medical Research ◽

10.31525/ct1-nct04115072 ◽

2019 ◽

Author(s):

Keyword(s):

Proof Of Concept ◽

Concept Study ◽

Download Full-text

A Proof of Concept Study of the Efficacy and Safety of Oral LAT8881 in Acute Migraine

Case Medical Research ◽

10.31525/ct1-nct04153409 ◽

2019 ◽

Author(s):

Keyword(s):

Acute Migraine ◽

Proof Of Concept ◽

Efficacy And Safety ◽

Download Full-text

A Mechanism Based Proof of Concept Study of the Effects of Duloxetine in the Treatment of Patients With Osteoarthritic Knee Pain

Case Medical Research ◽

10.31525/ct1-nct04224584 ◽

2020 ◽

Author(s):

Keyword(s):

Knee Pain ◽

Proof Of Concept ◽

Osteoarthritic Knee ◽

Download Full-text

Faculty Opinions recommendation of The safety, tolerance, pharmacokinetic and pharmacodynamic effects of single doses of AT-1001 in coeliac disease subjects: a proof of concept study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1091061.544445 ◽

2007 ◽

Author(s):

Ingvar Bjarnason

Keyword(s):

Coeliac Disease ◽

Proof Of Concept ◽

Concept Study ◽

Pharmacodynamic Effects

Download Full-text