Faculty Opinions recommendation of Targeted adsorption of molecules in the colon with the novel adsorbent-based medicinal product, DAV132: A proof of concept study in healthy subjects.

2016 ◽  
Author(s):  
José Luis Martínez
Keyword(s):  
Medicinal Product ◽  
Healthy Subjects ◽  
The Novel ◽  
Proof Of Concept ◽  
Concept Study

Targeted adsorption of molecules in the colon with the novel adsorbent-based Medicinal Product, DAV132: A proof of concept study in healthy subjects

2014 ◽  
Vol 55 (1) ◽  
pp. 10-16 ◽  
Author(s):  
Jean de Gunzburg ◽  
Annie Ducher ◽  
Christiane Modess ◽  
Danilo Wegner ◽  
Stefan Oswald ◽  
...  
Keyword(s):  
Medicinal Product ◽  
Healthy Subjects ◽  
The Novel ◽  
Proof Of Concept ◽  
Concept Study

scholarly journals The novel vasopressin receptor (V1aR) antagonist SRX246 reduces anxiety in an experimental model in humans: a randomized proof-of-concept study

2021 ◽  
Author(s):  
Tiffany R. Lago ◽  
Michael J. Brownstein ◽  
Emily Page ◽  
Emily Beydler ◽  
Adrienne Manbeck ◽  
...  
Keyword(s):  
Experimental Model ◽  
Vasopressin Receptor ◽  
The Novel ◽  
Proof Of Concept ◽  
Concept Study

The Feasibility of Using Augmented Auditory Feedback From a Pressure Detecting Insole to Reduce the Knee Adduction Moment: A Proof of Concept Study

2016 ◽  
Vol 138 (2) ◽  
Author(s):  
Christopher Ferrigno ◽  
Ina S. Stoller ◽  
Najia Shakoor ◽  
Laura E. Thorp ◽  
Markus A. Wimmer
Keyword(s):  
Auditory Feedback ◽  
Knee Flexion ◽  
Healthy Subjects ◽  
Knee Adduction Moment ◽  
Proof Of Concept ◽  
Normal Walking ◽  
Concept Study ◽  
Peak Knee ◽  
Flexion Moment ◽  
Gait Modification

The objective of this work was to conduct a proof of concept study utilizing auditory feedback from a pressure-detecting shoe insole to shift plantar pressure medially in order to reduce the knee adduction moment (KAM). When compared with normal walking, 32 healthy subjects significantly reduced their peak KAM using feedback (p < 0.001). When compared with medial thrust gait, an established gait modification, walking with pressure-based feedback was equally effective at reducing the peak KAM, yet it successfully mitigated other potentially detrimental gait measures such as the peak knee flexion moment (KFM), knee internal rotation moment (KIrM), and a reduction in speed.

Pharmacokinetics and Pharmacodynamic Effects of Oral GLP-1 and PYY3-36: A Proof-of-concept Study in Healthy Subjects

2008 ◽  
Vol 84 (4) ◽  
pp. 468-474 ◽  
Author(s):  
C Beglinger ◽  
B Poller ◽  
E Arbit ◽  
C Ganzoni ◽  
S Gass ◽  
...  
Keyword(s):  
Healthy Subjects ◽  
Proof Of Concept ◽  
Concept Study ◽  
Pharmacodynamic Effects
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