Separation and identification of compounds in Adinandra nitida by comprehensive two-dimensional liquid chromatography coupled to atmospheric pressure chemical ionization source ion trap tandem mass spectrometry

2006 ◽  
Vol 386 (3) ◽  
pp. 586-593 ◽  
Author(s):  
Jie Zhang ◽  
Dingyin Tao ◽  
Jicheng Duan ◽  
Zhen Liang ◽  
Weibing Zhang ◽  
...  
Keyword(s):  
Atmospheric Pressure ◽  
Chemical Ionization ◽  
Ion Trap ◽  
Atmospheric Pressure Chemical Ionization ◽  
Tandem Mass ◽  
Two Dimensional ◽  
Ionization Source ◽  
Chemical Ionization Source ◽  
Pressure Chemical Ionization ◽  
Pressure Chemical

scholarly journals Determination of Glucosamine in Human Plasma by High-Performance Liquid Chromatography-Atmospheric Pressure Chemical Ionization Source-Tandem Mass Spectrometry

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Xingchen Zhou ◽  
Zeneng Cheng ◽  
Liling Ran ◽  
Xin Guo ◽  
Zhi Liu ◽  
...  
Keyword(s):  
Atmospheric Pressure ◽  
High Performance ◽  
Chemical Ionization ◽  
Atmospheric Pressure Chemical Ionization ◽  
Tandem Mass ◽  
Ionization Source ◽  
Chemical Ionization Source ◽  
Pressure Chemical Ionization ◽  
Pressure Chemical

A sensitive, specific, and rapid high-performance liquid chromatography-atmospheric pressure chemical ionization source-tandem mass spectrometry (HPLC-APCI-MS/MS) method for the determination of glucosamine in human plasma was developed and validated. Plasma samples were processed by protein precipitation with dehydrated ethanol, and the chromatographic separation was performed on an Agilent XDB-C18 column with a mobile phase of methanol—0.2% formic acid solution (70 : 30, v/v). Mass spectrometric quantification was carried out in the multiple reaction monitoring (MRM) mode, monitoring ion transitions of m/z 180.1 to m/z 162.1 with collision energy (CE) of 2 eV for glucosamine and m/z 181.1 to m/z 163.1 with CE of 2 eV for the internal standard (IS) in positive ion mode. The linear calibration curves covered a concentration range of 53.27–3409 ng/mL with a lower limit of quantification (LLOQ) of 53.27 ng/mL. The extraction recovery of glucosamine was greater than 101.7%. The intra- and interday precisions for glucosamine were less than 10%, and the accuracies were between 93.7% and 102.6%, determined from quality control (QC) samples of three representative concentrations. The method has been successfully applied to determining the plasma concentration of glucosamine in a clinical pharmacokinetic study involving 20 healthy Chinese male volunteers.

Atmospheric Pressure Chemical Ionization Source. 2. Desorption−Ionization for the Direct Analysis of Solid Compounds

2008 ◽  
Vol 80 (8) ◽  
pp. 2654-2663 ◽  
Author(s):  
Francisco J. Andrade ◽  
Jacob T. Shelley ◽  
William C. Wetzel ◽  
Michael R. Webb ◽  
Gerardo Gamez ◽  
...  
Keyword(s):  
Atmospheric Pressure ◽  
Chemical Ionization ◽  
Atmospheric Pressure Chemical Ionization ◽  
Direct Analysis ◽  
Ionization Source ◽  
Desorption Ionization ◽  
Chemical Ionization Source ◽  
Pressure Chemical Ionization ◽  
Pressure Chemical ◽  
Solid Compounds

Atmospheric Pressure Chemical Ionization Source. 1. Ionization of Compounds in the Gas Phase

2008 ◽  
Vol 80 (8) ◽  
pp. 2646-2653 ◽  
Author(s):  
Francisco J. Andrade ◽  
Jacob T. Shelley ◽  
William C. Wetzel ◽  
Michael R. Webb ◽  
Gerardo Gamez ◽  
...  
Keyword(s):  
Gas Phase ◽  
Atmospheric Pressure ◽  
Chemical Ionization ◽  
Atmospheric Pressure Chemical Ionization ◽  
Ionization Source ◽  
Chemical Ionization Source ◽  
Pressure Chemical Ionization ◽  
Pressure Chemical

Microchip Atmospheric Pressure Chemical Ionization Source for Mass Spectrometry

2004 ◽  
Vol 76 (22) ◽  
pp. 6659-6664 ◽  
Author(s):  
Pekka Östman ◽  
Seppo J. Marttila ◽  
Tapio Kotiaho ◽  
Sami Franssila ◽  
Risto Kostiainen
Keyword(s):  
Mass Spectrometry ◽  
Atmospheric Pressure ◽  
Chemical Ionization ◽  
Atmospheric Pressure Chemical Ionization ◽  
Ionization Source ◽  
Chemical Ionization Source ◽  
Pressure Chemical Ionization ◽  
Pressure Chemical

Combined Electrospray Ionization−Atmospheric Pressure Chemical Ionization Source for Use in High-Throughput LC−MS Applications

2003 ◽  
Vol 75 (4) ◽  
pp. 973-977 ◽  
Author(s):  
Richard T. Gallagher ◽  
Michael P. Balogh ◽  
Paul Davey ◽  
Mike R. Jackson ◽  
Ian Sinclair ◽  
...  
Keyword(s):  
Electrospray Ionization ◽  
High Throughput ◽  
Atmospheric Pressure ◽  
Chemical Ionization ◽  
Atmospheric Pressure Chemical Ionization ◽  
Ionization Source ◽  
Chemical Ionization Source ◽  
Pressure Chemical Ionization ◽  
Pressure Chemical
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