Temporal changes in reversible cerebral ischemia on perfusion- and diffusion-weighted magnetic resonance imaging: the value of relative cerebral blood volume maps

2002 ◽  
Vol 44 (2) ◽  
pp. 103-108 ◽  
Author(s):  
S. Lee, D. Kim, E. Jeong, P. Yoon, S.
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cerebral Ischemia ◽  
Magnetic Resonance ◽  
Blood Volume ◽  
Cerebral Blood Volume ◽  
Temporal Changes ◽  
Resonance Imaging ◽  
Relative Cerebral Blood Volume ◽  
Weighted Magnetic Resonance Imaging ◽  
And Diffusion

scholarly journals Cerebral Hemodynamics in Human Acute Ischemic Stroke: A Study with Diffusion- and Perfusion-Weighted Magnetic Resonance Imaging and SPECT

2000 ◽  
Vol 20 (6) ◽  
pp. 910-920 ◽  
Author(s):  
Yawu Liu ◽  
Jari O. Karonen ◽  
Ritva L. Vanninen ◽  
Leif Østergaard ◽  
Reina Roivainen ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Ischemic Stroke ◽  
Magnetic Resonance ◽  
Acute Ischemic Stroke ◽  
Blood Volume ◽  
Cerebral Blood Volume ◽  
Acute Stage ◽  
Resonance Imaging ◽  
Relative Cerebral Blood Volume ◽  
Ischemic Tissue

Nineteen patients with acute ischemic stroke (<24 hours) underwent diffusion-weighted and perfusion-weighted (PWI) magnetic resonance imaging at the acute stage and 1 week later. Eleven patients also underwent technetium-99m ethyl cysteinate dimer single-photon emission computed tomography (SPECT) at the acute stage. Relative (ischemic vs. contralateral control) cerebral blood flow (relCBF), relative cerebral blood volume, and relative mean transit time were measured in the ischemic core, in the area of infarct growth, and in the eventually viable ischemic tissue on PWI maps. The relCBF was also measured from SPECT. There was a curvilinear relationship between the relCBF measured from PWI and SPECT ( r = 0.854; P < 0.001). The tissue proceeding to infarction during the follow-up had significantly lower initial CBF and cerebral blood volume values on PWI maps ( P < 0.001) than the eventually viable ischemic tissue had. The best value for discriminating the area of infarct growth from the eventually viable ischemic tissue was 48% for PWI relCBF and 87% for PWI relative cerebral blood volume. Combined diffusion and perfusion-weighted imaging enables one to detect hemodynamically different subregions inside the initial perfusion abnormality. Tissue survival may be different in these subregions and may be predicted.

scholarly journals Relation between Relative Cerebral Blood Flow, Relative Cerebral Blood Volume, and Mean Transit Time in Patients with Acute Ischemic Stroke Determined by Perfusion-Weighted MRI

2003 ◽  
Vol 23 (5) ◽  
pp. 605-611 ◽  
Author(s):  
Oliver C. Singer ◽  
Richard du Mesnil de Rochemont ◽  
Christian Foerch ◽  
Astrid Stengel ◽  
Heiner Lanfermann ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Magnetic Resonance ◽  
Blood Volume ◽  
Cerebral Blood Volume ◽  
Mean Transit Time ◽  
Resonance Imaging ◽  
Unaffected Side ◽  
Weighted Magnetic Resonance Imaging

The relation between relative cerebral blood flow (relCBF), relative cerebral blood volume (relCBV), and mean transit time (MTT) changes was examined in 20 patients with acute cerebral ischemia (<6 h) using perfusion-weighted magnetic resonance imaging. Regions of interest (ROI) were selected on MTT maps covering the entire MTT abnormal cortical area. These ROIs were transferred to the relCBF and relCBV maps to analyze the relation between relCBF, relCBV, and MTT on a voxel-by-voxel basis. On the unaffected side, a tight coupling of relCBF and relCBV was found with little variation of MTT. In hypoperfused cortex, relCBV was increased at all investigated relCBF categories, and there was greater relCBV variability than on the unaffected side. Only a severe decrease of relCBF, to less than 0.3, in comparison with the unaffected side was associated with a reduction of relCBV less than 1.0. In contrast to the unaffected side, a power law function (relCBV = 2.283 × relCBF0.549) resulted in a better fit than using a linear function for the correlation of relCBF and relCBV. MTT ratios increased steadily with decreasing CBF values. In conclusion, there is a clear relation between different perfusion-weighted magnetic resonance imaging parameters in acute ischemia, reflecting both the degree of hemodynamic failure as well as compensatory mechanisms including vasodilation.

Temporal evolution of focal cerebral ischemia in the rat assessed by T2-weighted and diffusion-weighted magnetic resonance imaging

1992 ◽  
Vol 5 (2) ◽  
pp. 171-176 ◽  
Author(s):  
H. B. Verheul ◽  
J. W. Berkelbach van der Sprenkel ◽  
C. A. F. Tulleken ◽  
K. S. Tamminga ◽  
K. Nicolay
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cerebral Ischemia ◽  
Magnetic Resonance ◽  
Temporal Evolution ◽  
Focal Cerebral Ischemia ◽  
Resonance Imaging ◽  
Diffusion Weighted ◽  
Weighted Magnetic Resonance Imaging ◽  
And Diffusion

scholarly journals Evaluation of combined bevacizumab plus irinotecan therapy in brain tumors using magnetic resonance imaging measures of relative cerebral blood volume

2011 ◽  
Vol 68 (4) ◽  
pp. 1266-1272 ◽  
Author(s):  
Kimberly R. Pechman ◽  
Deborah L. Donohoe ◽  
Devyani P. Bedekar ◽  
Shekar N. Kurpad ◽  
Kathleen M. Schmainda
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Brain Tumors ◽  
Blood Volume ◽  
Cerebral Blood Volume ◽  
Resonance Imaging ◽  
Relative Cerebral Blood Volume

scholarly journals Diagnosis of Acute Ischemic Stroke Based on Time-To-Peak and Diffusion-Weighted Magnetic Resonance Imaging.

2002 ◽  
Vol 42 (7) ◽  
pp. 281-288
Author(s):  
Keisuke MARUYAMA ◽  
Tsuneyoshi EGUCHI ◽  
Shigeo SORA ◽  
Masafumi IZUMI ◽  
Hirofumi HIYAMA ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Ischemic Stroke ◽  
Magnetic Resonance ◽  
Acute Ischemic Stroke ◽  
Resonance Imaging ◽  
Time To Peak ◽  
Diffusion Weighted ◽  
Weighted Magnetic Resonance Imaging ◽  
And Diffusion
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