scholarly journals Contrast-enhanced ultrasound of benign and malignant liver lesions in children

2021 ◽  
Author(s):  
Cheng Fang ◽  
Sudha A. Anupindi ◽  
Susan J. Back ◽  
Doris Franke ◽  
Thomas G. Green ◽  
...  
Keyword(s):  
Liver Lesion ◽  
Focal Liver Lesion ◽  
Ultrasound Contrast Agents ◽  
Focal Liver Lesions ◽  
Liver Lesions ◽  
Contrast Enhanced Ultrasound ◽  
Cross Sectional ◽  
Pediatric Liver ◽  
Contrast Enhanced

AbstractContrast-enhanced ultrasound (CEUS) is increasingly being used in children. One of the most common referrals for CEUS performance is characterization of indeterminate focal liver lesions and follow-up of known liver lesions. In this setting, CEUS is performed with intravenous administration of ultrasound contrast agents (UCAs). When injected into a vein, UCA microbubbles remain confined within the vascular network until they dissipate. Therefore, visualization of UCA within the tissues and lesions corresponds to true blood flow. CEUS enables continuous, real-time observation of the enhancement pattern of a focal liver lesion, allowing in most cases for a definite diagnosis and obviating the need for further cross-sectional imaging or other interventional procedures. The recent approval of Lumason (Bracco Diagnostics, Monroe Township, NJ) for pediatric liver CEUS applications has spurred the widespread use of CEUS. In this review article we describe the role of CEUS in pediatric liver applications, focusing on the examination technique and interpretation of main imaging findings of the most commonly encountered benign and malignant focal liver lesions. We also compare the diagnostic performance of CEUS with other imaging modalities for accurate characterization of focal liver lesions.

scholarly journals Characterization of a hepatic haemangioma with contrast-enhanced ultrasound in an infant

Ultrasound ◽  
2017 ◽  
Vol 26 (3) ◽  
pp. 178-181 ◽  
Author(s):  
Marta Anna Piorkowska ◽  
Rok Dezman ◽  
Maria E Sellars ◽  
Annamaria Deganello ◽  
Paul S Sidhu
Keyword(s):  
Imaging Techniques ◽  
Paediatric Population ◽  
Liver Lesion ◽  
Focal Liver Lesion ◽  
Focal Liver Lesions ◽  
Contrast Enhanced Ultrasound ◽  
Safe Alternative ◽  
Contrast Enhanced ◽  
Hepatic Haemangioma

Focal liver lesions are uncommon in the paediatric population, majority are benign but need to be clearly identified as benign. Contrast-enhanced ultrasound has recently received approval for paediatric hepatic use and represents an inexpensive and safe alternative to computed tomography and magnetic resonance imaging for focal liver lesion characterization. We report a case of an incidental focal liver lesion in a four-month-old infant, indeterminate on B-mode ultrasound but successfully characterized with contrast-enhanced ultrasound as a haemangioma, without recourse to other imaging techniques, and with minimal patient discomfort.

scholarly journals Role of contrast enhanced ultrasound in characterization of focal liver lesions

2014 ◽  
Vol 45 (1) ◽  
pp. 7-17 ◽  
Author(s):  
Shruti Thakur ◽  
Anupam Jhobta ◽  
D.S. Dhiman ◽  
R.G. Sood ◽  
Arun Chauhan ◽  
...  
Keyword(s):  
Focal Liver Lesions ◽  
Liver Lesions ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced

Contrast-Enhanced Ultrasound in the Characterization of Complex Cystic Focal Liver Lesions

2015 ◽  
Vol 41 (5) ◽  
pp. 1301-1310 ◽  
Author(s):  
A. Corvino ◽  
O. Catalano ◽  
S.V. Setola ◽  
F. Sandomenico ◽  
F. Corvino ◽  
...  
Keyword(s):  
Focal Liver Lesions ◽  
Liver Lesions ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced

Characterization of Focal Liver Lesions by Contrast Enhanced Ultrasound (CEUS) in Clinical Practice – A Bicentric Experience

2011 ◽  
Vol 140 (5) ◽  
pp. S-926-S-927
Author(s):  
Ioan Sporea ◽  
Radu Badea ◽  
Alina Popescu ◽  
Alina F. Martie ◽  
Mihai Socaciu ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Focal Liver Lesions ◽  
Liver Lesions ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced

scholarly journals Characterization of Focal Liver Lesions using Contrast Enhanced Ultrasound as a First Line Method: a Large Monocentric Experience

2014 ◽  
Vol 23 (1) ◽  
pp. 57-63 ◽  
Author(s):  
Ioan Sporea ◽  
Alina Martie ◽  
Simona Bota ◽  
Roxana Sirli ◽  
Alina Popescu ◽  
...  
Keyword(s):  
Focal Liver Lesions ◽  
Imaging Method ◽  
Liver Lesions ◽  
Contrast Enhanced Ultrasound ◽  
First Line ◽  
Clear Cut ◽  
Contrast Enhanced ◽  
Line Imaging ◽  
Conclusive Diagnosis

Aim: To present a large monocentric experience in the characterization of focal liver lesions (FLLs) using Contrast Enhanced Ultrasound (CEUS).Method: A retrospective study was performed in the Gastroenterology and Hepatology Department, Timisoara, including 1100 patients with 1329 FLLs evaluated between September 2009 and January 2013. A CEUS examination was considered conclusive if the FLL respected the typical enhancement pattern as described in the EFSUMB Guidelines.Results: From the 1329 FLLs, CEUS was conclusive for a specific pathology in 1102 cases (82.9%). For the differentiation of benign/malignant lesions, CEUS reached a conclusive diagnosis in 1196 (90%) cases. The percentage of conclusive CEUS examinations was significantly higher in patients without chronic liver disease as compared with those with chronic hepatopathies: 87.3% vs. 74.4% (p<0.0001).Conclusion: CEUS patterns of enhancement fell into clear cut specific diagnostic patterns in 83% of the FLLs discovered by US, and into clear cut benign versus malignant patterns in 90% of the cases. For this reason, we can strongly recommend CEUS as a first line imaging method to characterize FLLs found at US, at least in centers with a good experience in CEUS.

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