Recent advances in the metabolic engineering of microorganisms for the production of 3-hydroxypropionic acid as C3 platform chemical

2013 ◽  
Vol 97 (8) ◽  
pp. 3309-3321 ◽  
Author(s):  
Kris Niño G. Valdehuesa ◽  
Huaiwei Liu ◽  
Grace M. Nisola ◽  
Wook-Jin Chung ◽  
Seung Hwan Lee ◽  
...  
2021 ◽  
pp. 107722
Author(s):  
Atrayee Chattopadhyay ◽  
Mohor Mitra ◽  
Mrinal K. Maiti

Author(s):  
Ruohao Tang ◽  
Qifeng Wen ◽  
Meijie Li ◽  
Wei Zhang ◽  
Zhaobao Wang ◽  
...  

2020 ◽  
Vol 37 (1) ◽  
pp. 80-99 ◽  
Author(s):  
Meijie Li ◽  
Feifei Hou ◽  
Tong Wu ◽  
Xinglin Jiang ◽  
Fuli Li ◽  
...  

This review covers the strategies mostly developed in the last three years for microbial production of isoprenoid, classified according to the engineering targets.


2019 ◽  
Vol 51 ◽  
pp. 99-109 ◽  
Author(s):  
Hee Taek Kim ◽  
Tae Uk Khang ◽  
Kei-Anne Baritugo ◽  
Sung Min Hyun ◽  
Kyoung Hee Kang ◽  
...  

2013 ◽  
Vol 31 (6) ◽  
pp. 945-961 ◽  
Author(s):  
Vinod Kumar ◽  
Somasundar Ashok ◽  
Sunghoon Park

2017 ◽  
Vol 62 (2) ◽  
pp. 156 ◽  
Author(s):  
Aladár Vidra ◽  
Áron Németh

3-hydroxypropionic acid is a commercially valuable, important platform chemical. It can serve as a precursor for several key compound, such as acrylic acid, 1,3-propanediol, methyl acrylate, acrylamide, ethyl 3-HP, malonic acid, propiolactone and acrylonitrile. Several microorganisms can produce through a range of metabolic pathways. It is indispensable for the commercial production of 3-HP to use cheap and abundant substrates and also to produce in highly efficient processes which could result high yield, titer and productivity. Because  of the fact, that natural microorganism do not perform these conditions, metabolic engineering and genetically engineered microorganism are widely used for research and production as well. Several metabolic pathways are introduced to utilize glucose or glycerol for 3-HP production. In this overview naturally producer microorganisms, synthetic biochemical pathways, results from the recent years and recovery of 3-HP are detailed.


2016 ◽  
Vol 34 ◽  
pp. 60-70 ◽  
Author(s):  
Yunpeng Wang ◽  
Tao Sun ◽  
Xingyan Gao ◽  
Mengliang Shi ◽  
Lina Wu ◽  
...  

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