Influence of intrapartum antibiotic prophylaxis against group B Streptococcus on the early newborn gut composition and evaluation of the anti-Streptococcus activity of Bifidobacterium strains

Author(s):  
Irene Aloisio ◽  
Giuseppe Mazzola ◽  
Luigi Tommaso Corvaglia ◽  
Giacomo Tonti ◽  
Giacomo Faldella ◽  
...  
2014 ◽  
Vol 129 (1) ◽  
pp. 9-12 ◽  
Author(s):  
Santiago Scasso ◽  
Joel Laufer ◽  
Grisel Rodriguez ◽  
Justo G. Alonso ◽  
Claudio G. Sosa

2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Sebastian Faro ◽  
Brenda Brehm ◽  
Frances Smith ◽  
Melanie Mouzoon ◽  
Anthony Greisinger ◽  
...  

Objective. To assess the effect of universal screening and administration of intrapartum antibiotic prophylaxis to prevent early-onset neonatal GBS sepsis at a private tertiary care hospital since issuance of the 2002 CDC guidelines for preventing perinatal GBS disease.Methods. Retrospective analysis of women delivering between January 1, 2003 and December 31, 2004 at a private tertiary care hospital in Houston, Texas. The percentage of women screened, GBS positive women receiving intrapartum antibiotic prophylaxis, and infants developing early-onset GBS sepsis were determined.Results. 2,108 women delivered 2,135 infants with 1,874 (89%) screened for GBS. Of those screened, 1,322 (71%) tested negative and 552 (29%) tested positive for GBS. In this analysis of 2,135 infants, 3 (0.94 cases/1,000 live births) were diagnosed with invasive GBS sepsis.Conclusion. High rates of screening of pregnant women for GBS colonization and use of intrapartum antibiotic prophylaxis for GBS carriers can be achieved in a private tertiary care hospital setting. “Synopsis: High screening rates for group B streptococcus in a private tertiary care hospital reduce the incidence of maternal and early onset neonatal GBS infection.”


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