PTEN hamartoma of the soft tissue: the initial manifestation of an underlying PTEN hamartoma tumor syndrome in a 4-year-old female

2017 ◽  
Vol 46 (11) ◽  
pp. 1591-1595 ◽  
Author(s):  
Charles B. Chism ◽  
Lindsay Crawford ◽  
Amanda Tchakarov ◽  
Alyaa Al-Ibraheemi ◽  
Nicholas M. Beckmann
Keyword(s):  
Soft Tissue ◽  
Initial Manifestation ◽  
Pten Hamartoma Tumor Syndrome

scholarly journals A Challenging Diagnosis: PTEN Hamartoma Tumor Syndrome Presenting as Isolated Soft-tissue Vascular Anomalies

2021 ◽  
Vol 2 (2) ◽  
pp. e011
Author(s):  
Lauren R. S. Hill ◽  
Jessica Duis ◽  
Ann M. Kulungowski ◽  
Aparna Annam ◽  
Bradford Siegele ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Vascular Anomalies ◽  
Pten Hamartoma Tumor Syndrome

A SOFT TISSUE EXTRANODAL MASS AS AN INITIAL MANIFESTATION OF SPLENIC LYMPHOMA WITH CIRCULATING VILLOUS LYMPHOCYTES

1998 ◽  
Vol 103 (4) ◽  
pp. 1213-1214 ◽  
Author(s):  
Ma Teresa Orero ◽  
Amparo Miguel-Sosa ◽  
Estella Matutes ◽  
Alicia Miguel-Garcia ◽  
Fernando Hernández ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Initial Manifestation ◽  
Splenic Lymphoma

Soft Tissue Metastasis as Initial Manifestation of Pleural Malignant Mesothelioma

1999 ◽  
Vol 7 (1) ◽  
pp. 39-44
Author(s):  
Javier A. Laurini ◽  
Teresa Castiglioni ◽  
Boris Elsner ◽  
Alejandra Avagnina ◽  
Santiago Ferreiro ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Malignant Mesothelioma ◽  
Soft Tissue Metastasis ◽  
Initial Manifestation ◽  
Pleural Malignant Mesothelioma

Langerhans cell histiocytosis in a 5-month-old presenting with biparietal masses

2010 ◽  
Vol 6 (4) ◽  
pp. 393-397 ◽  
Author(s):  
Katie L. Pricola ◽  
Jason Karamchandani ◽  
Hannes Vogel ◽  
Gary V. Dahl ◽  
Kristen W. Yeom ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Langerhans Cell Histiocytosis ◽  
Pediatric Population ◽  
Treatment Strategies ◽  
Langerhans Cell ◽  
Surrounding Tissue ◽  
Multisystem Disease ◽  
Initial Manifestation ◽  
Early Presentation ◽  
Radiographic Appearance

Langerhans cell histiocytosis (LCH) is a rare proliferative disorder that occurs most commonly in the pediatric population as a result of pathological clonal proliferation of Langerhans cells with subsequent damage and destruction to surrounding tissue. Clinically, LCH presents in a variety of ways, which often results in prolonged time to diagnosis and subsequently poorer outcomes. In this case report, the authors describe an unusually early presentation of multisystem LCH in a patient at birth, which resulted in a 5-month delay to diagnosis and treatment. This patient presented both atypically young and with an uncommon initial manifestation of multisystem disease with multiple soft-tissue swellings rather than early skin involvement. Additionally, this patient had an unusual radiographic appearance with biparietal skull destruction on initial skull radiographs and biparietal soft-tissue lesions on CT resembling cephalohematoma at 3 months of age. The clinical and radiological evaluation, pathology, and treatment strategies are discussed, with particular attention paid to the importance of further workup of atypical nonresolving cephalohematomas to prevent disease progression and poorer outcomes.

scholarly journals Acute Cardiac Tamponade Secondary to Cardiac Vascular-Type Pleomorphic Leiomyosarcoma: Case Report

2021 ◽  
pp. 1860-1867
Author(s):  
Ricardo Fernández-Ferreira ◽  
Pamela Denisse Soberanis-piña ◽  
Emilio Conde-Flores ◽  
Andrés Mauricio Arroyave-Ramírez ◽  
Ileana Mackinney-Novelo ◽  
...  
Keyword(s):  
Case Report ◽  
Surgical Treatment ◽  
Soft Tissue ◽  
Pulmonary Artery ◽  
Cardiac Tamponade ◽  
Clinical Case ◽  
Soft Tissue Sarcomas ◽  
Initial Manifestation ◽  
Vascular Type ◽  
Great Vessels

Soft tissue sarcomas represent <1% of all neoplasms. Leiomyosarcomas comprise only 5–7% of cases, and only 2% of these are vascular. Vascular leiomyosarcomas are extremely rare and represent only 0.001% of all neoplasms, the venous type being up to 5 times more frequent. Arterial leiomyosarcomas most frequently affect the great vessels, being fatal in most cases. In the reported cases of arterial leiomyosarcomas, the most frequently affected site is the pulmonary artery. We present the clinical case of 2 patients (a 42-year-old woman and a 36-year-old man) with a diagnosis of arterial pleomorphic leiomyosarcoma that conditioned cardiac tamponade as the initial manifestation. As it is an exceptionally rare neoplasm and with few cases reported in the literature, it is important to identify and describe this pathology which, due to the impossibility of offering surgical treatment, represents a therapeutic challenge.

Localization of Gallium-67 in Peritoneal Cells by Electron Microscopic Autoradiography

1973 ◽  
Vol 31 ◽  
pp. 404-405
Author(s):  
D. C. Swartzendruber ◽  
Norma L. Idoyaga-Vargas
Keyword(s):  
Clinical Trials ◽  
Soft Tissue ◽  
Tumor Tissue ◽  
Soft Tissue Tumors ◽  
Clinical Usefulness ◽  
Electron Microscopic ◽  
Normal Cells ◽  
Electron Microscopic Autoradiography ◽  
Peritoneal Cells ◽  
Gallium 67

The radionuclide gallium-67 (67Ga) localizes preferentially but not specifically in many human and experimental soft-tissue tumors. Because of this localization, 67Ga is used in clinical trials to detect humar. cancers by external scintiscanning methods. However, the fact that 67Ga does not localize specifically in tumors requires for its eventual clinical usefulness a fuller understanding of the mechanisms that control its deposition in both malignant and normal cells. We have previously reported that 67Ga localizes in lysosomal-like bodies, notably, although not exclusively, in macrophages of the spocytaneous AKR thymoma. Further studies on the uptake of 67Ga by macrophages are needed to determine whether there are factors related to malignancy that might alter the localization of 67Ga in these cells and thus provide clues to discovering the mechanism of 67Ga localization in tumor tissue.

Morphological Examination of a Herpes-type Virus Indigenous for Tree Shrews

1970 ◽  
Vol 28 ◽  
pp. 160-161
Author(s):  
J. P. Brunschwig ◽  
R. M. McCombs ◽  
R. Mirkovic ◽  
M. Benyesh-Melnick
Keyword(s):  
Electron Microscopy ◽  
Soft Tissue ◽  
Chick Embryo ◽  
Soft Tissue Sarcoma ◽  
Cell Cultures ◽  
Tree Shrew ◽  
Type Virus ◽  
Morphological Examination ◽  
Tree Shrews ◽  
Embryo Cells

A new virus, established as a member of the herpesvirus group by electron microscopy, was isolated from spontaneously degenerating cell cultures derived from the kidneys and lungs of two normal tree shrews. The virus was found to replicate best in cells derived from the homologous species. The cells used were a tree shrew cell line, T-23, which was derived from a spontaneous soft tissue sarcoma. The virus did not multiply or did so poorly for a limited number of passages in human, monkey, rodent, rabbit or chick embryo cells. In the T-23 cells, the virus behaved as members of the subgroup B of herpesvirus, in that the virus remained primarily cell associated.

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